| David Jonathan Franklin Limited | Information & communication | 2025 |
| David Offord Consult Ltd | Professional & scientific | 2018 |
| David Stanton Consulting Limited | Information & communication | 2016 |
| Davida Counselling Ltd | Health & social care | 2021 |
| Dawes Green Developments Limited | Real estate | 2016 |
| Daymer Group Limited | Financial services | 2025 |
| Daytime Healthcare Recruitment Limited | Administrative & support | 2015 |
| Daytime Homecare Limited | Administrative & support | 2019 |
| DC CTO Consulting Ltd | Information & communication | 2025 |
| DDC Management Consultancy Ltd | Professional & scientific | 2025 |
| DDP Coding and Art Services Limited | Information & communication | 2020 |
| DE Souza Consultancy Limited | Professional & scientific | 2023 |
| DE Souza Consulting Limited | Professional & scientific | 2023 |
| DEA Property Investment Limited | Households | 2022 |
| DEA Solutions Limited | Professional & scientific | 2025 |
| Dead Letters Productions Limited | Information & communication | 2024 |
| Dean and Shepherd Limited | Wholesale & retail | 2013 |
| Dean Group Management UK Limited | Hospitality | 2025 |
| Deane EHS Ltd | Professional & scientific | 2025 |
| Debbie Does Salad Ltd | Wholesale & retail | 2022 |
| Debut Studios Concessions Limited | Arts & recreation | 2023 |
| Debut Studios Tattoo Limited | Arts & recreation | 2020 |
| Deckbridge Limited | Construction | 1980 |
| Decorivo Ltd | Construction | 2013 |
| DEE James Limited | Professional & scientific | 2019 |
| Deep Cycles Ltd | Wholesale & retail | 2024 |
| Deep Earth Energy Technology Limited | Wholesale & retail | 2025 |
| Deep Earth Minerals Limited | Administrative & support | 2021 |
| Deer Cafe Limited | Hospitality | 2022 |
| Deetyasoft Limited | Real estate | 2022 |
| Defiant Outdoor Limited | Professional & scientific | 2025 |
| Degfont (UK) Limited | Construction | 2016 |
| Deia Studios Fashion Ltd | Wholesale & retail | 2022 |
| Dekom UK Ltd | Information & communication | 2021 |
| Delayed & Paid Ltd | Hospitality | 2017 |
| Delectus Limited | Professional & scientific | 2011 |
| Deli Deli UK Limited | Hospitality | 2011 |
| Dellino Solutions Limited | Information & communication | 2019 |
| Delta Partnership Consultancy Ltd | Professional & scientific | 2011 |
| Demarcation Films Ltd. | Information & communication | 2015 |
| Denarius Capital Ltd | Financial services | 2023 |
| Dengab Ltd | Wholesale & retail | 2024 |
| Denkimono Ltd | Information & communication | 2016 |
| Denovas Solutions Ltd | Professional & scientific | 2017 |
| Dentoptic Limited | Real estate | 2002 |
| Derwent Communications Limited | Professional & scientific | 2004 |
| Desert Cedar Limited | Information & communication | 1996 |
| Desi Stars Ltd | Hospitality | 2019 |
| Design Disrupters Limited | Wholesale & retail | 2017 |
| Design Illumine Ltd | Real estate | 1989 |
| Design in Progress Limited | Administrative & support | 2010 |
| Design Narrative Ltd | Administrative & support | 2014 |
| Designza Ltd | Information & communication | 2019 |
| Destiny Software Consulting Limited | Information & communication | 2020 |
| Desultory Ventures Limited | Wholesale & retail | 2022 |
| Detail One Limited | Arts & recreation | 2014 |
| Devedup Ltd | Information & communication | 2011 |
| Dever Consultancy Ltd | Information & communication | 2018 |
| Devi's Jewels Limited | Information & communication | 2025 |
| Devom Estates Ltd | Real estate | 2024 |
| Devom Properties Ltd | Real estate | 2015 |
| Devon Power Ltd. | Professional & scientific | 2013 |
| Devonport 45 Ltd. | Construction | 2019 |
| Devonshire Mews Develco Limited | Real estate | 2017 |
| DFP Building Services Ltd | Construction | 2023 |
| DG Media Rights Ltd | Administrative & support | 2016 |
| DGA Consulting Limited | Financial services | 2016 |
| DGE Hand Packing Ltd | Administrative & support | 2014 |
| DGM Property Investments Limited | Real estate | 2014 |
| DGN Mobile and Vape Ltd | Wholesale & retail | 2024 |
| Dgree Ltd | Professional & scientific | 2019 |
| DH Critical Care Professionals Ltd | Health & social care | 2018 |
| Dhan Guru Nanak Limited | Wholesale & retail | 2020 |
| Dhan Guru Nanak Property Ltd | Real estate | 2026 |
| Dhayan Maintenance Services Limited | Manufacturing | 2004 |
| DI Consultancy Ltd | Construction | 2023 |
| Diadem Homes Limited | Construction | 2002 |
| Diamond Kingston Limited | Hospitality | 2012 |
| Dickerage Estates Limited | Real estate | 2026 |
| Didi Medical Limited | Health & social care | 2021 |
| Digital Diamond Ltd | Wholesale & retail | 2023 |
| Digital Growth Equity Ltd | Information & communication | 2021 |
| Digital Propositions Ltd | Information & communication | 2023 |
| Digital Strategy Limited | Extraterritorial | 2023 |
| Digitalcraft Consulting Limited | Information & communication | 2016 |
| Digitaldata Consulting Limited | Information & communication | 2015 |
| Dilanuk Ltd | Financial services | 2024 |
| Dincer Consultancy Ltd | Transport & logistics | 2025 |
| Dinny Shaw Planning Limited | Extraterritorial | 2023 |
| Dipley Limited | Hospitality | 2007 |
| Direct Bar Management Ltd | Information & communication | 2020 |
| Direct U.K. Transport Limited | Information & communication | 1995 |
| Dirk Energy Ltd | Professional & scientific | 2025 |
| Discern Consultants Ltd | Information & communication | 2026 |
| Disho Trading Ltd | Wholesale & retail | 2019 |
| Disruptive Development Limited | Information & communication | 2020 |
| Ditton Lawn Residents Company Limited | Households | 1987 |
| Diverse Video Limited | Information & communication | 2021 |
| Diverse Voices Ltd | Professional & scientific | 2004 |
| Diverse Worldwide Trading Limited | Financial services | 2024 |