| Copperfields Chillington Management Company Limited | Households | 2011 |
| Coral and Mint Ltd | Wholesale & retail | 2020 |
| Cotmore Farm Limited | Agriculture & fishing | 2011 |
| Couch Joinery Ltd | Manufacturing | 2023 |
| Court Farm (Amenities) Limited | Households | 1997 |
| Court Lane Owners Management Company Ltd. | Households | 2017 |
| Court Park Management Limited | Households | 1986 |
| Cove Designs by Laura Ltd | Manufacturing | 2021 |
| Crabshell Heights (Kingsbridge) Management Limited | Households | 2007 |
| Crabshell Quay Management Limited | Administrative & support | 2002 |
| Craig Douglas Consultants Ltd | Professional & scientific | 2026 |
| Craig Fortescue Consulting Ltd | Professional & scientific | 2025 |
| CRE Properties Limited | Construction | 2008 |
| Creaturus Ltd. | Agriculture & fishing | 2021 |
| Creek END Management Company Limited | Households | 2003 |
| Crisis Capable Ltd | Professional & scientific | 2026 |
| Culver Rise Management Limited | Households | 2020 |
| Cuming Containers Ltd | Water & waste | 2020 |
| Cura Heritage Ltd | Professional & scientific | 2026 |
| Curraghmore Capital Ltd | Real estate | 2020 |
| D H F Limited | Households | 2014 |
| D P Property Developments Limited | Real estate | 2002 |
| D&G Nails Ltd | Other services | 2024 |
| D.J. Fisher (Agricultural Contractor) Limited | Agriculture & fishing | 2011 |
| D.M. Fabrications (SW) Ltd | Construction | 2005 |
| D.W.M. Contractors Limited | Agriculture & fishing | 2013 |
| D2O Architects Ltd | Professional & scientific | 2023 |
| DAN Cheshire Design Limited | Professional & scientific | 2010 |
| DAN F Limited | Wholesale & retail | 2013 |
| Dans Waste Removal & Skip Hire Limited | Water & waste | 2025 |
| Dartmouth LEE Court Residents Limited | Real estate | 1983 |
| Datafarm AI Ltd | Administrative & support | 2025 |
| Daughters of Gaea Ltd | Wholesale & retail | 2019 |
| Davis Building (SW) Limited | Construction | 2004 |
| Dennings Development Limited | Construction | 2024 |
| Dentick Limited | Manufacturing | 2006 |
| Devon Coastal Cottages Limited | Hospitality | 2019 |
| Devon Home & Life Organisers Limited | Construction | 2015 |
| Devon Inns Limited | Hospitality | 2018 |
| Devon Party Walls Ltd | Construction | 2018 |
| Devon Property Specialists Ltd. | Administrative & support | 2015 |
| Devon Secure Storage Ltd | Real estate | 2019 |
| Devon Woodman Ltd | Administrative & support | 2024 |
| Devonfields 2022 Limited | Professional & scientific | 2022 |
| Devonfields Limited | Construction | 1985 |
| Diamond Addiction Limited | Wholesale & retail | 2002 |
| Diamond Finish Valeting Ltd | Administrative & support | 2017 |
| Discovery Surf Ltd | Arts & recreation | 2016 |
| Disruptive Thinking Limited | Information & communication | 2017 |
| Dittiscombe Valley Experiences Ltd | Hospitality | 2021 |
| Dixton House Limited | Professional & scientific | 2002 |
| Dkhp Holdings Limited | Financial services | 2018 |
| DO YOU Love This Planet Ltd | Arts & recreation | 2017 |
| Dodbrooke Court Residents Association Limited | Households | 1987 |
| Dodbrooke Lodge Limited | Households | 2001 |
| Dodbrooke Manor Limited | Administrative & support | 2017 |
| Dolce Vita Group Ltd | Education | 2009 |
| Dolce Vita Guides Ltd | Education | 2010 |
| Dolphin Land & Development Consultancy Ltd | Construction | 2006 |
| Donnelly Consulting Services Ltd | Professional & scientific | 2024 |
| Downs Thurlestone Management Company Limited(The) | Households | 1982 |
| E-Xplore Devon Limited | Arts & recreation | 2019 |
| E.& B. R. Noyce Limited | Professional & scientific | 1962 |
| Eagles Acro Ltd | Arts & recreation | 2006 |
| East Soar Outdoor Experience LLP | | 2011 |
| Eastacoombes Way (Alston Gate) Management Company Ltd | Households | 2015 |
| Easton Farm (Kingsbridge) Limited | Real estate | 1945 |
| Easychauffeur Limited | Transport & logistics | 2003 |
| Eco Plant Pack Ltd | Manufacturing | 2024 |
| Ecology Developments Ltd | Construction | 2015 |
| Eddystone Miller Limited | Professional & scientific | 2010 |
| Edible Space Limited | Information & communication | 2014 |
| Education South West | Education | 2010 |
| EJ Dalton Limited | Wholesale & retail | 2022 |
| ELEVAN68 Ltd | Wholesale & retail | 2025 |
| Elfwood Investment Co. Limited | Real estate | 1965 |
| Elliott Hire Limited | Construction | 2013 |
| Elly Wentworth Ltd | Professional & scientific | 2023 |
| Elston Park Management Company Limited | Households | 1992 |
| EM & M Investments Ltd | Real estate | 2023 |
| Emily Braine Property Services Limited | Real estate | 2022 |
| Endurancelife Ltd | Arts & recreation | 2007 |
| Entangled Earth Collective CIC | Education | 2025 |
| Entroptix Limited | Administrative & support | 2001 |
| Envest Limited | Other services | 2002 |
| Essex Learning Partnership Limited | Education | 2012 |
| Estuary Edge Management Company Limited | Households | 2017 |
| Evolution Blue Limited | Extraterritorial | 2021 |
| F1 Plumbing & Heating South West Ltd | Construction | 2017 |
| Fablinens and Cleans Ltd | Administrative & support | 2026 |
| Fallapit Estate Management Company Limited | Real estate | 2008 |
| Family Advice Support Team (Fast) CIC | Health & social care | 2013 |
| Farm Pizza Plymouth Limited | Hospitality | 2024 |
| Fatnap Media Limited | Financial services | 2018 |
| Favour Hub Ltd | Wholesale & retail | 2019 |
| Feast Events Ltd | Hospitality | 2020 |
| Field and Beach Property Management Ltd | Hospitality | 2023 |
| Fika Kingsbridge Ltd | Hospitality | 2018 |
| Filmdrones Ltd | Professional & scientific | 2015 |
| Fine Shine Limited | Administrative & support | 2004 |