| Sdip Kimra Limited | Financial services | 2018 |
| Sdip Movebla Limited | Financial services | 2017 |
| Sdip Road Speed Control Limited | Financial services | 2018 |
| SDJ Comms Ltd | Construction | 2020 |
| Sea Words Ltd | Wholesale & retail | 2024 |
| Seabite Ltd | Other services | 2021 |
| Seafish Importers Limited | Wholesale & retail | 2011 |
| Seal Analytical Limited | Manufacturing | 2000 |
| Sealskinz Holdings Limited | Manufacturing | 2007 |
| Sealskinz Limited | Manufacturing | 2003 |
| Sealy Gill International Ltd | Information & communication | 2022 |
| Sean Kerry Wealth Management Limited | Financial services | 2014 |
| Seans Body Art Ltd | Other services | 2005 |
| Seastride Ltd | Real estate | 2021 |
| Seavio Limited | Information & communication | 2019 |
| Security Techniques UK Limited | Administrative & support | 2005 |
| Sedasoft Limited | Information & communication | 2001 |
| Sedgeford Financial Services Limited | Financial services | 1988 |
| Seer Provisions Ltd | Wholesale & retail | 2002 |
| Segovia Limited | Real estate | 2013 |
| Seiichan Limited | Transport & logistics | 2007 |
| Select Technology Solutions Ltd | Professional & scientific | 2009 |
| Sensus Architecture Ltd | Professional & scientific | 2016 |
| Sereal Properties LLP | | 2009 |
| Serenity Hair Emporium Ltd | Other services | 2003 |
| Serum Management Ltd | Professional & scientific | 2014 |
| Service Line, Catering Equipment Engineers Limited | Professional & scientific | 1989 |
| SET Accountants Limited | Professional & scientific | 2015 |
| SF4 Designs Ltd | Wholesale & retail | 2024 |
| SF4 Ltd | Financial services | 2010 |
| SG Carpentry and Build Limited | Manufacturing | 2020 |
| SG Group Norfolk Ltd | Extraterritorial | 2023 |
| SGB Property (West Norfolk) Limited | Real estate | 2014 |
| SH Online Ltd | Wholesale & retail | 2014 |
| SH Skip Hire Ltd | Water & waste | 2024 |
| Shafeek Anaesthetics Ltd | Health & social care | 2023 |
| Shake Awake 26 Ltd | Wholesale & retail | 2026 |
| Shakespeare's Guildhall Productions Ltd | Arts & recreation | 2019 |
| Shark Fabrication Technologies Ltd | Manufacturing | 2026 |
| Sharp Fabrications Limited | Manufacturing | 1998 |
| Sharp Laser Limited | Manufacturing | 2009 |
| Sharp Projects Limited | Extraterritorial | 2012 |
| Sharpe Snacks (Gosberton) Limited | Hospitality | 2003 |
| Shaun Hagen Motor Services Limited | Wholesale & retail | 2005 |
| Shaun Hodgson Engineering Limited | Manufacturing | 2001 |
| Shazsha Holdings Limited | Wholesale & retail | 2018 |
| SHE Shines Detailing Ltd | Wholesale & retail | 2023 |
| Sheader Marine Limited | Real estate | 1995 |
| Sheena's Kitchen Limited | Hospitality | 2025 |
| Sheils : Flynn Limited | Professional & scientific | 1997 |
| Shelsamain Limited | Information & communication | 1983 |
| Shepfry Ltd | Real estate | 2021 |
| Sheringham Court Freehold Ltd | Real estate | 2014 |
| Sheringham DRY Cleaners Limited | Other services | 2023 |
| Sheringham Properties Ltd | Construction | 2008 |
| SHF Structural Examinations Ltd | Other services | 2023 |
| Shielamitre Ltd | Health & social care | 2022 |
| Shift Photography Ltd | Professional & scientific | 2024 |
| Shiine Design Ltd | Professional & scientific | 2014 |
| Shiine Enterprise Ltd | Information & communication | 2010 |
| Shiine Ltd | Manufacturing | 2010 |
| Shiloh Property Limited | Professional & scientific | 2014 |
| Shimit and Viral Limited | Real estate | 2010 |
| Shodan Events Ltd | Other services | 2022 |
| Shooting Grey Ltd | Real estate | 2022 |
| Shortec IT Services Limited | Extraterritorial | 2013 |
| Shortstay England Limited | Manufacturing | 2019 |
| Showme.Fit Limited | Information & communication | 2020 |
| Shrimp Producers Organisation Limited | Other services | 2012 |
| Shumoo Limited | Information & communication | 2023 |
| Sidj Ltd | Transport & logistics | 2023 |
| Sidney's Home Care Ltd | Administrative & support | 2010 |
| Sigma Real Estate Ltd | Construction | 2002 |
| Signline (Yorkshire) Limited | Manufacturing | 2005 |
| Signs Near ME Ltd | Manufacturing | 2023 |
| Silfield Gardens Management (Hunstanton) Limited | Households | 1984 |
| Silver Fern Property Management Co. Ltd | Real estate | 1999 |
| Silver FOX 1961 Limited | Administrative & support | 2012 |
| Silver Sands (Heacham) Limited | Arts & recreation | 2007 |
| Silveroak Healthcare Ltd | Financial services | 2022 |
| Silverstar Chauffeur Service Ltd | Transport & logistics | 2015 |
| Simmons Autos Ltd | Wholesale & retail | 2023 |
| SIR Lewis Street Management Co. Limited. | Real estate | 2007 |
| Sirius Training & Certifications Ltd | Professional & scientific | 2015 |
| Sitavansh Ltd | Financial services | 2012 |
| Sitemove Property Management Limited | Real estate | 1993 |
| SJA Civils Management Ltd | Construction | 2024 |
| SJM Services (Norfolk) Ltd | Wholesale & retail | 2020 |
| SJS Leisure Limited | Arts & recreation | 2017 |
| SJT Plant Services Limited | Manufacturing | 2023 |
| SK Builders & Property Maitenance Ltd | Construction | 2026 |
| SKA Consultancy (Norfolk) Limited | Professional & scientific | 2026 |
| SKC Gold N Jewellery Ltd | Wholesale & retail | 2024 |
| Skinology Clinic Ltd | Health & social care | 2019 |
| Skip Archimedes Events Ltd | Administrative & support | 2020 |
| Sky Nails Ltd | Other services | 2023 |
| Skycraft UAV Limited | Professional & scientific | 2024 |
| Skye Holdings Norfolk Limited | Wholesale & retail | 2025 |
| Skylarks Pre-School Limited | Education | 2011 |
| Slanetrac Engineering UK Limited | Construction | 2019 |