| Proprico Ltd | Professional & scientific | 2015 |
| Punto Kilmacolm Ltd | Hospitality | 2024 |
| Queensferry Plumbing & Heating Limited | Construction | 1986 |
| Radical Marine Ltd | Wholesale & retail | 2022 |
| Rair Jewellery Ltd | Wholesale & retail | 2026 |
| Ramco Pipe Care Limited | Manufacturing | 2022 |
| Ranfurly Estates Limited | Construction | 1989 |
| Ranfurly Property Holdings Limited | Real estate | 2021 |
| RDM Scotland Ltd. | Construction | 2015 |
| Rebel Coco Limited | Wholesale & retail | 2017 |
| Red Star Skene Ltd | Hospitality | 2019 |
| Renderworks Ltd | Construction | 2015 |
| Renfrew Logistics 2 Limited | Real estate | 2025 |
| Replan Living Global Ltd | Professional & scientific | 2024 |
| Reselltcg Ltd | Wholesale & retail | 2025 |
| Resolve Psychotherapy Ltd | Real estate | 2022 |
| Rhythm Base Limited | Wholesale & retail | 2005 |
| River Ccyf Limited | Professional & scientific | 2015 |
| Riverside LOG Cabins Ltd | Real estate | 2014 |
| RJP 2023 Ltd | Financial services | 2023 |
| Roofx Ltd | Construction | 2023 |
| Rosemount Management Services Limited | Professional & scientific | 2016 |
| RS & SL Smith Limited | Health & social care | 2014 |
| Rubislaw DEN Consultancy Limited | Professional & scientific | 2012 |
| Ryan Plant Recycling Ltd | Water & waste | 2013 |
| Sabrepearl Limited | Households | 1999 |
| Sammax Investments M | Financial services | 2016 |
| Sammax Investments S | Financial services | 2016 |
| Sammax Property Holdings | Real estate | 2017 |
| Sapp Kilmacolm Flats Limited | Financial services | 2023 |
| Sapp Property Holdings Limited | Financial services | 2023 |
| Sapp Property Limited | Real estate | 2016 |
| Sarah Haran Accessories Limited | Manufacturing | 2017 |
| Scented Scotland Ltd. | Wholesale & retail | 2008 |
| Scotia Business Solutions Ltd | Professional & scientific | 2020 |
| Scotlander Limited | Professional & scientific | 2011 |
| SCS Retail Properties Limited | Real estate | 2009 |
| Sheils Construction Joinery & Maintenance Limited | Construction | 2014 |
| Shelterstone Ltd | Real estate | 2020 |
| Silver Lining Debt Relief Ltd | Professional & scientific | 2019 |
| Silver Service (Scotland) Ltd | Health & social care | 2019 |
| Single Point of Contact Ltd | Information & communication | 2022 |
| Skin Scotland Ltd | Other services | 2015 |
| Smith Packaging Aerospace Ltd | Administrative & support | 2026 |
| Smith Packaging Solutions Limited | Professional & scientific | 2015 |
| Sole Solution Scotland Limited | Wholesale & retail | 2016 |
| Spokes Bikes Limited | Wholesale & retail | 2020 |
| ST Columba's School (Construction) Limited | Construction | 2000 |
| ST Columba's School (Developments) Limited | Real estate | 2000 |
| ST James Terrace PHC Ltd | Real estate | 2025 |
| ST James Terrace Trading Ltd | Hospitality | 2025 |
| ST Olive Ltd | Administrative & support | 2023 |
| ST. Columba's School Limited | Other services | 1932 |
| Stanecastle Software Limited | Information & communication | 2003 |
| Stecla Technology Limited | Wholesale & retail | 2026 |
| Stella Wholesale Limited | Wholesale & retail | 2015 |
| Stocktaking Services (Scotland) Limited | Professional & scientific | 2001 |
| Strait Top Limited | Professional & scientific | 2023 |
| Stramash Production Ltd. | Professional & scientific | 2010 |
| STRATOV8 Limited | Professional & scientific | 2021 |
| Stuart Reekie Golf Ltd | Wholesale & retail | 2019 |
| Subi and Sons Ltd | Construction | 2021 |
| Supply Chain Results Limited | Professional & scientific | 2022 |
| Swingmatch AI Ltd | Information & communication | 2026 |
| T and R Medical Ltd | Wholesale & retail | 2024 |
| T Grip Limited | Information & communication | 2015 |
| T.S.C.M. Limited | Real estate | 1999 |
| T.V.E. 2 Limited | Construction | 2018 |
| Tackling Matters CIC | Arts & recreation | 2025 |
| TCL Computer Solutions Ltd | Information & communication | 2015 |
| Teachers Web Limited | Administrative & support | 2020 |
| Teen Challenge Strathclyde | Other services | 1994 |
| Tenps Ltd | Information & communication | 2015 |
| Tergeo Scotland Limited | Households | 2011 |
| THE Cargill Cafe Ltd | Hospitality | 2018 |
| THE Cross Books and Coffee Shop Ltd | Wholesale & retail | 2026 |
| THE Haven Kilmacolm | Health & social care | 2003 |
| THE Healthcare Collection Limited | Health & social care | 2022 |
| THE Kilmacolm and Port Glasgow Agricultural Society | Education | 2009 |
| THE Kilmacolm New Community Centre Company | Other services | 2003 |
| THE Mull GIN Company Ltd | Manufacturing | 2018 |
| THE Mull GIN Distillery Ltd | Manufacturing | 2018 |
| THE Pet Shop Postie Limited | Wholesale & retail | 2014 |
| THE Plan Design and Manufacture Limited | Manufacturing | 2009 |
| THE Sammax Property Company | Financial services | 2017 |
| THE Tyre Shop (Scotland) Limited | Wholesale & retail | 2014 |
| Thornhill Glass & Glazing Limited | Construction | 2005 |
| Trade Right International C.I.C | Administrative & support | 2008 |
| Transatlantic Partners Limited | Wholesale & retail | 2017 |
| Trisul Solutions Ltd. | Professional & scientific | 2007 |
| Urban Creatures Ltd | Professional & scientific | 2009 |
| Ursinic (IP) Limited | Manufacturing | 2023 |
| Ursinic Limited | Manufacturing | 2022 |
| VGE Consulting Ltd | Administrative & support | 2007 |
| VINO13 Limited | Wholesale & retail | 2015 |
| W Gibb Stuart Limited | Wholesale & retail | 1974 |
| Water ROW Investments Limited | Real estate | 2021 |
| WCA Acquisitions Limited | Wholesale & retail | 2012 |
| WEE Bike Hub Limited | Arts & recreation | 2018 |
| Wellness by Waters Ltd | Health & social care | 2020 |