| R.E Civil Engineering Ltd | Construction | 2021 |
| RAJ K Consulting Limited | Professional & scientific | 2026 |
| RAJ KG Management Ltd | Financial services | 2026 |
| Rays of Hope Cancer Support | Education | 2023 |
| RBZ Properties Ltd | Real estate | 2025 |
| Rees Management Solutions Ltd | Real estate | 2014 |
| Reiki Ready Ltd | Health & social care | 2025 |
| Renfrewshire CAB Co Ltd | Transport & logistics | 2017 |
| Renfrewshire Optical Company Ltd | Wholesale & retail | 2018 |
| Renfrewshire Radio Taxis Limited | Transport & logistics | 1996 |
| REO Stakis Hydro Limited | Professional & scientific | 2014 |
| REO Stakis Limited | Agriculture & fishing | 2007 |
| Reportlink Ltd | Administrative & support | 2016 |
| Response Cleaning Services Ltd | Administrative & support | 2018 |
| Revive Love & Life Complementary Therapies Ltd. | Health & social care | 2017 |
| Ricc Metallurgical Ltd | Professional & scientific | 2025 |
| Riddell Thoms & Company LLP | | 2003 |
| Rio's Vips Dog Walking & Training Ltd | Agriculture & fishing | 2025 |
| River Inn (Holdings) Limited | Real estate | 2024 |
| River Inn (Trading) Limited | Hospitality | 2024 |
| RJF Solutions (Scotland) Ltd | Construction | 2023 |
| RK Diving Services Ltd | Manufacturing | 2020 |
| Rmbl Consulting Ltd | Professional & scientific | 2023 |
| Rmck Electrical Services Limited | Construction | 2018 |
| Road Dog Logistics Ltd | Transport & logistics | 2026 |
| Roar-Connections for Life Ltd | Health & social care | 2010 |
| Robert Geary Ltd | Wholesale & retail | 2017 |
| Robertson Decorator Services Ltd | Construction | 2021 |
| Rock Drive Studios Ltd | Information & communication | 2018 |
| Rocmob Limited | Health & social care | 2018 |
| Ropes and Rigs Ltd | Construction | 2025 |
| Roselle Rovers Ltd | Arts & recreation | 2025 |
| Roslyn House Loch Ness Operations Limited | Hospitality | 2025 |
| Ross Alan Vint Ltd | Health & social care | 2019 |
| Roundhill Project Management Limited | Professional & scientific | 2006 |
| Rowanfield Limited | Real estate | 1991 |
| RS Security Systems Ltd | Administrative & support | 2025 |
| Ruddock Company Ltd | Administrative & support | 2025 |
| Rusalco Solutions Limited | Information & communication | 2010 |
| RWH Health & Safety Advisor Ltd | Professional & scientific | 2025 |
| Rybond Limited | Administrative & support | 1998 |
| RZR Barbers Ltd | Other services | 2024 |
| S Kerr Ltd | Construction | 2026 |
| S Mccurdy and Sons Limited | Construction | 2019 |
| S S Shan Properties Ltd | Real estate | 2026 |
| S Wilson Vehicle Repairs Ltd | Wholesale & retail | 2019 |
| S.D Coachworks Ltd | Manufacturing | 2019 |
| S.J Mcgowan Rail Ltd | Construction | 2017 |
| S.J.Mcgowan Installations Ltd | Construction | 2020 |
| Sabidrive Ltd | Education | 2026 |
| Safehouse Services Limited | Administrative & support | 2025 |
| Saltire Shooting Range Ltd | Other services | 2026 |
| Salus Security Scotland Limited | Administrative & support | 2023 |
| Sameer's Pizza Ltd | Hospitality | 2025 |
| Sami Amir & Co Limited | Professional & scientific | 2025 |
| Sandy Flats Food Store Ltd | Wholesale & retail | 2022 |
| Sanupama Consulting Limited | Professional & scientific | 2014 |
| Saor Forestry Limited | Agriculture & fishing | 2019 |
| Saorsa Menopause Consultancy Ltd | Health & social care | 2022 |
| Scale Model Vehicles Ltd | Wholesale & retail | 2025 |
| Scotia Project & Engineering Partners Ltd | Professional & scientific | 2025 |
| Scott Bruce Electrical Ltd | Construction | 2022 |
| Scott RAE IT Services Limited | Information & communication | 2009 |
| Scott's Golf Shop Ltd | Arts & recreation | 2017 |
| Scottish Chiropractic Association | Other services | 1992 |
| SD Turner Engineering Ltd | Other services | 2012 |
| SDL Consulting (UK) Ltd | Professional & scientific | 2011 |
| SDT Johnstone Ltd | Hospitality | 2026 |
| SF Roofing & Cladding Ltd | Construction | 2025 |
| SGA (Scotland) Holdings Limited | Financial services | 2019 |
| SGR Cleaning Services Limited | Administrative & support | 2025 |
| Shake and Bake (Scotland) Limited | Arts & recreation | 2018 |
| Shepherd TCG Ltd | Wholesale & retail | 2026 |
| Shillinglaws Agencies Ltd | Other services | 2017 |
| Shimla Catering Ltd | Hospitality | 2026 |
| Shopholic Ltd | Wholesale & retail | 2024 |
| Signature Aesthetics Clinic Ltd | Health & social care | 2017 |
| Signature Developments Ltd | Real estate | 2024 |
| Silent Spring Group Limited | Professional & scientific | 2020 |
| Silver FRY Ltd | Hospitality | 2026 |
| Sinclair Craig Limited | Professional & scientific | 2015 |
| Single Point Events Limited | Wholesale & retail | 2013 |
| Site Engineering Ltd | Extraterritorial | 2024 |
| Sjmtech Limited | Professional & scientific | 2023 |
| SK Jewellers (Scotland) Ltd | Wholesale & retail | 2021 |
| SLIKK7 Ltd | Professional & scientific | 2016 |
| SLS Dance Ltd | Education | 2022 |
| SM Trustee Limited | Financial services | 2024 |
| Smith & Mclaurin Group Limited | Professional & scientific | 2006 |
| Smith & Mclaurin Holdings Limited | Manufacturing | 2013 |
| Smith & Mclaurin Limited | Manufacturing | 2002 |
| SMJ Contracts Ltd | Wholesale & retail | 2024 |
| SML Johnstone Limited | Hospitality | 2025 |
| Smld Ltd | Hospitality | 2014 |
| Social Recluse (Clothing) Ltd | Wholesale & retail | 2022 |
| Source & Design International (UK) Limited | Administrative & support | 2001 |
| Southmains Mechanical Services Limited | Manufacturing | 1999 |
| SP Groundcare Ltd | Administrative & support | 2024 |
| Sparkles Cleaning Scotland Ltd | Administrative & support | 2016 |
| Spateston Newsagents Ltd | Wholesale & retail | 2015 |