| L F Julian Limited | Financial services | 2018 |
| L J Butt Ltd | Construction | 2024 |
| L Walke Ltd | Transport & logistics | 2017 |
| L&L Fencing and Waste Services Ltd | Other services | 2019 |
| Laids Ltd | Construction | 2015 |
| Lapmaster Wolters Limited | Manufacturing | 1954 |
| Laserwest Limited | Manufacturing | 1984 |
| Laurel Commercial Plymouth Ltd | Wholesale & retail | 2023 |
| Lawrence Holdings SW Ltd | Real estate | 2023 |
| Laws Land Labour Ltd | Agriculture & fishing | 2018 |
| LC Boutique Limited | Other services | 2026 |
| LCT Services Ltd | Professional & scientific | 2025 |
| LDJ Plumbing & Heating Ltd | Construction | 2026 |
| LEA Property Management Ltd | Real estate | 2018 |
| Leak Busters SW Ltd | Construction | 2026 |
| Leal Services Ltd | Information & communication | 2026 |
| LEE Mill Eateries Limited | Hospitality | 2017 |
| LEE Mill Garden Machinery Ltd | Other services | 2022 |
| Legacy Drone Services Ltd | Professional & scientific | 2026 |
| Lelle & Co Limited | Administrative & support | 2015 |
| Lend a Helping Hand C.I.C. | Professional & scientific | 2023 |
| LEO Management Solutions Ltd | Professional & scientific | 2022 |
| Level Cleaning Ltd | Administrative & support | 2025 |
| Lewis Haughton Wills Ltd | Real estate | 2010 |
| Liftsafe SW Ltd | Construction | 2026 |
| Lighthouse Safety Solutions Limited | Public administration | 2025 |
| Lilfords Ltd | Professional & scientific | 2010 |
| Lils Collective Limited | Wholesale & retail | 2025 |
| Lincoln Incorporated Limited | Extraterritorial | 2012 |
| Lines Investments Limited | Financial services | 2024 |
| Lions Share 1 Ltd | Financial services | 2023 |
| Liquorice World Ltd | Wholesale & retail | 2022 |
| Lisa Gowing Mortgage Advice Limited | Financial services | 2025 |
| Little Moor Haven Ltd | Arts & recreation | 2024 |
| Little Otter Party Supplies Limited | Wholesale & retail | 2018 |
| Live Controls Limited | Construction | 2009 |
| Live in the South Ltd | Arts & recreation | 2024 |
| LJB Developments (South West) Ltd | Real estate | 2013 |
| LK Foods Plymouth Ltd | Hospitality | 2023 |
| LKM Scaffolding Limited | Construction | 2024 |
| Llewellynn Smith Inns Limited | Hospitality | 2003 |
| Llivoc Management Ltd | Real estate | 2026 |
| LMB Property Management Limited | Real estate | 2024 |
| Locky's Autos Ltd | Wholesale & retail | 2025 |
| London SW Communications Limited | Wholesale & retail | 2015 |
| Lone Wolf Services Ltd | Administrative & support | 2025 |
| Lord Electrical (SW) Limited | Manufacturing | 2013 |
| Lordprice Limited | Information & communication | 2003 |
| LOX Corporations Ltd | Hospitality | 2024 |
| LP Pictures Limited | Information & communication | 2004 |
| LPL Solutions Ltd | Wholesale & retail | 2026 |
| LPR Plastering & Building Ltd | Construction | 2024 |
| LPR Plastering & Construction Ltd | Construction | 2025 |
| LRC Marine Limited | Professional & scientific | 2026 |
| LSK Building Contractors Ltd | Construction | 2010 |
| Ludbrook Foods Limited | Manufacturing | 2015 |
| Luna Logistics Limited | Transport & logistics | 2022 |
| M & M Plumbing & Heating Limited | Construction | 2006 |
| M and M Refinishing Ltd | Other services | 2023 |
| M C H Automotive Limited | Manufacturing | 2021 |
| M H M Design Ltd | Professional & scientific | 2007 |
| M J Stallard Limited | Agriculture & fishing | 2002 |
| M Sanderson NDT Limited | Other services | 2023 |
| M Sarker Limited | Hospitality | 2024 |
| M&J Prynn Ltd | Mining & quarrying | 2014 |
| Macmillan Martial Arts Academy Limited | Arts & recreation | 2014 |
| MAGPIE59 Solutions Limited | Construction | 2024 |
| Mainline and Metro Limited | Professional & scientific | 1997 |
| Maitlands Residential Lettings Limited | Real estate | 2019 |
| Mar-Lin (Ivybridge) Limited | Construction | 2021 |
| Marco's Trattoria LLP | | 2022 |
| Marians Maples Development Limited | Construction | 2019 |
| Marine Composites Ltd | Manufacturing | 2024 |
| Mark Charles Homer Automotive Services Ltd | Wholesale & retail | 2018 |
| Martin LEY Plumbing and Heating Ltd | Construction | 2013 |
| Masterkey Locksmiths SW Limited | Manufacturing | 2025 |
| Matrix People LLP | | 2020 |
| Matt Harvey Property Expert Limited | Real estate | 2023 |
| Maverick & Mace Ltd | Wholesale & retail | 2022 |
| MAX 48 Ltd | Hospitality | 2020 |
| Mayflower Plymouth Ltd | Hospitality | 2025 |
| MBC (Devon) Limited | Administrative & support | 2004 |
| MBF Care Ltd. | Health & social care | 1999 |
| Mccowsill Properties Limited | Real estate | 2021 |
| Mcleod Bros(Contractors)Limited | Real estate | 1959 |
| Mead My Day - Virtual Assistant Limited | Professional & scientific | 2025 |
| Meadow Wood Pet Crematorium Ltd | Other services | 2020 |
| Megabox Mysteries Limited | Wholesale & retail | 2025 |
| Meghna Ivybridge Ltd | Hospitality | 2015 |
| Mena Homes Ltd | Construction | 2013 |
| Mewstone Mortgage Advice Ltd | Financial services | 2020 |
| Michaelstow Holiday Village Limited | Professional & scientific | 1978 |
| Mike Lane Mods Limited | Manufacturing | 2018 |
| Mike Lewis Builders Limited | Construction | 2006 |
| Milkshakes SW Ltd | Hospitality | 2025 |
| Millbrook Inn South Pool Limited | Hospitality | 2026 |
| Million Dollar Aesthetics by Ally Limited | Other services | 2024 |
| Millmans Properties Limited | Construction | 2010 |
| Millswood Nurseries Limited | Health & social care | 2012 |
| Mine the GAP Ltd | Hospitality | 2012 |