| UNIT-2 (Torquay) Ltd | Real estate | 2012 |
| Unity Production (SW) Ltd | Administrative & support | 2022 |
| Urban Blue (SW) Limited | Real estate | 2016 |
| Urbanshield Roofing & Cladding Ltd | Construction | 2026 |
| V.I.P. Environmental Cleaning Ltd | Other services | 2007 |
| Vanilla Hair & Beauty Plymouth Limited | Other services | 2024 |
| Vantage South West Ltd | Professional & scientific | 2025 |
| VBT Group Limited | Wholesale & retail | 2026 |
| Vendesi Homes Ltd | Real estate | 2026 |
| Victoria Bolt Estate Agents Ltd | Real estate | 2022 |
| Victoria Garage Ivybridge Ltd | Wholesale & retail | 2018 |
| Victoria House Surgery Limited | Health & social care | 2013 |
| Victory Tattoo Company Limited | Other services | 2026 |
| Vigh Ventures Ltd | Financial services | 2021 |
| Viking Interiors Ltd | Construction | 2021 |
| Viktoria Howden Training Ltd | Professional & scientific | 2025 |
| Vine Orchard Management Limited | Real estate | 2026 |
| VIP Class Acts Ltd | Education | 2026 |
| Visceral Escape Limited | Hospitality | 2021 |
| Vision Distribution SW Ltd | Transport & logistics | 2023 |
| Vision Flying Services Limited | Hospitality | 2014 |
| Vitruvian Fitness Ltd | Health & social care | 2024 |
| Voice Creative Design & Marketing Limited | Information & communication | 2013 |
| Vuelta Ltd | Wholesale & retail | 2017 |
| Vusvo Ltd | Professional & scientific | 2024 |
| W.G. Friend and SON Limited | Wholesale & retail | 1988 |
| Wakeley's Limited | Wholesale & retail | 2008 |
| Walkers Autocare Ltd | Wholesale & retail | 2022 |
| Wall Gems Ltd | Professional & scientific | 2022 |
| Walruspubplymouth Ltd | Hospitality | 2022 |
| Warwick Insight Limited | Professional & scientific | 1999 |
| Water and Stone Ltd | Other services | 2021 |
| Water and Warmth Services (South West) Limited | Construction | 1991 |
| Wave Boards Ltd | Manufacturing | 2018 |
| WAVE7DIGITAL Ltd | Professional & scientific | 2023 |
| Waye Farm Management Company Limited | Professional & scientific | 1989 |
| Wbar Limited | Wholesale & retail | 2022 |
| Weatherhead ERC Limited | Extraterritorial | 2021 |
| Weatherhead Shop Designers Limited | Construction | 2004 |
| Webb South West Limited | Transport & logistics | 2007 |
| Webbers Autos Limited | Wholesale & retail | 2025 |
| Webbers Bodyshop Limited | Wholesale & retail | 2024 |
| Well Actually Ltd | Wholesale & retail | 2026 |
| Wellington Property Solutions Limited | Households | 2024 |
| West Country Composites Ltd | Professional & scientific | 2026 |
| West Country Electrical Limited | Construction | 2017 |
| West Country Marine Services Limited | Manufacturing | 2016 |
| West Country Recovery (SW) Ltd | Transport & logistics | 2023 |
| Westcountry Commercials Ltd | Wholesale & retail | 2022 |
| Westcountry Schools Trust | Education | 2010 |
| Western Carpets & Pine Limited | Construction | 2000 |
| Western Education Solutions Ltd | Education | 2023 |
| Westgate Films Ltd | Information & communication | 2006 |
| Westhaven Freight Solution Ltd | Transport & logistics | 2022 |
| Westlake Ventures Ltd | Hospitality | 2023 |
| Weston Farm Developments Limited | Construction | 2018 |
| White Room Productions Limited | Information & communication | 2018 |
| White Room Tattoo Limited | Other services | 2016 |
| Whiteoaks Management Company Limited | Real estate | 2024 |
| Whitesails Accountants Limited | Professional & scientific | 2022 |
| Widland Farm Cottages Management Company Limited | Households | 1993 |
| Widodo Ltd | Arts & recreation | 2025 |
| Wild Tipi Ltd | Arts & recreation | 2016 |
| Will Erith Consultancy & Advisory Services Limited | Professional & scientific | 2024 |
| Willand O&M Limited | Professional & scientific | 2017 |
| Wills Family Investment Co Ltd | Real estate | 2017 |
| Wills Marine Holdings Limited | Wholesale & retail | 2007 |
| Winter Wonderland (Exeter) Ltd | Administrative & support | 2023 |
| WOK Fusion Restaurant Ltd | Hospitality | 2023 |
| Wombat Cricket Limited | Manufacturing | 2015 |
| Wombat Willow Limited | Agriculture & fishing | 2017 |
| Woodbrook Online Limited | Information & communication | 2008 |
| Woodbury Properties SW Limited | Households | 2025 |
| Wooduchoose Limited | Wholesale & retail | 2012 |
| Wrangaton Body Repairs Ltd | Wholesale & retail | 2017 |
| Wrist & Root Ltd | Wholesale & retail | 2025 |
| XL Technical Group Ltd | Arts & recreation | 2023 |
| Xtreme Professional Carpet & Upholstery Cleaning Ltd | Administrative & support | 2025 |
| Xtreme Specialist Cleaning Services Ltd | Administrative & support | 2025 |
| Yealm Estates Limited | Construction | 2024 |
| Ykdrl Ltd | Wholesale & retail | 2026 |
| Your Home LET Limited | Real estate | 2019 |
| Youth Self Defence Ltd | Education | 2024 |
| Zakho Barber Ltd | Other services | 2018 |
| Zarabelle Studios Limited | Other services | 2025 |
| ZEN Entertainment Ltd | Hospitality | 2019 |
| Zenith Solutions SW Ltd | Professional & scientific | 2025 |
| Zeynep Properties Ltd | Real estate | 2025 |
| Zras Consulting Ltd | Professional & scientific | 2024 |