| Diagonal View Limited | Information & communication | 2008 |
| Diamas Coaching Ltd | Other services | 2017 |
| Diana Gorenco Limited | Arts & recreation | 2023 |
| Digital Dreams Games Ltd | Information & communication | 2020 |
| Digital Dreams Services Ltd | Information & communication | 2021 |
| Dimi Works Ltd | Construction | 2019 |
| Dimovi 2025 Corporation Ltd | Transport & logistics | 2025 |
| Dinero Supply Ltd | Wholesale & retail | 2025 |
| Dino's Journey Cafe Ltd | Manufacturing | 2025 |
| Dion Developments Ltd | Construction | 2018 |
| Dion Homes Ltd | Construction | 2019 |
| Dion Management Ltd | Construction | 2019 |
| Directed Voices Limited | Information & communication | 2022 |
| Discount Bazaar Express Ltd | Wholesale & retail | 2025 |
| Distek Limited | Information & communication | 1998 |
| Divine Details Limited | Administrative & support | 2025 |
| Divine Nexus Limited | Professional & scientific | 2016 |
| Divine Shape LLP | | 2023 |
| Divis Investments Ltd | Real estate | 2023 |
| DJ Roofing (Essex) Limited | Construction | 2026 |
| Djlm Limited | Information & communication | 2010 |
| Dkrb Limited | Professional & scientific | 2025 |
| DM Gardens Ltd | Administrative & support | 2020 |
| DM10 Properties Ltd | Professional & scientific | 1993 |
| DMC4 Rail Limited | Manufacturing | 2015 |
| DMT London Ltd | Wholesale & retail | 2019 |
| DNA Apps Limited | Information & communication | 2015 |
| DNA Championship Ltd | Arts & recreation | 2026 |
| DNA Chauffeur and Tours Ltd | Administrative & support | 2023 |
| DOC London Limited | Manufacturing | 2016 |
| Doggies Furever Ltd | Other services | 2023 |
| Dokal Enterprises Limited | Real estate | 2015 |
| Dolce Only Ltd | Professional & scientific | 2025 |
| Dolphin TV Limited | Information & communication | 2011 |
| Dolphins Childcare Limited | Health & social care | 2017 |
| Domaxis Limited | Real estate | 2016 |
| Dominic & Dominic Limited | Construction | 2022 |
| DON Investment Holdings Ltd | Financial services | 2025 |
| Dondi Smith Limited | Administrative & support | 2026 |
| Done.Dusted Clean Services UK Ltd | Administrative & support | 2026 |
| Dontel Roofing Supplies (Depot 3) Limited | Wholesale & retail | 2024 |
| Dontel Roofing Supplies (Depot 4) Limited | Wholesale & retail | 2024 |
| Dontel Roofing Supplies (Depot 5) Limited | Wholesale & retail | 2025 |
| Dontel Roofing Supplies (Depot 6) Limited | Wholesale & retail | 2025 |
| Dontel Roofing Supplies (Depot 7) Limited | Wholesale & retail | 2025 |
| Dontel Roofing Supplies (Depot 8) Limited | Wholesale & retail | 2025 |
| Dontel Roofing Supplies Limited | Wholesale & retail | 2003 |
| Dooa Limited | Real estate | 2019 |
| Dorebar Limited | Mining & quarrying | 2024 |
| Dorling Holdings Limited | Financial services | 2019 |
| Dotleap Ltd | Wholesale & retail | 2017 |
| DPT Travel Limited | Transport & logistics | 2014 |
| DR Fit Foods Limited | Hospitality | 2025 |
| DR M Sung Medical Services Ltd | Health & social care | 2022 |
| DR Property Services Ltd | Professional & scientific | 2015 |
| DR S RAO Ltd | Health & social care | 2012 |
| DR Seymour Limited | Health & social care | 2024 |
| Dragutin Popovic Ltd | Other services | 2023 |
| Drain Pro Ltd | Water & waste | 2026 |
| Drainage Hero Guys Ltd | Water & waste | 2025 |
| Draq Limited | Information & communication | 2012 |
| Dream Big Living Limited | Health & social care | 2019 |
| Dream Home Decorators Limited | Construction | 2024 |
| Dream Homes West London Ltd | Construction | 2019 |
| Dreammedic Ltd | Real estate | 2022 |
| Dreamstay Tours UK Ltd | Administrative & support | 2026 |
| Driftwood Realty Solutions Ltd | Real estate | 2024 |
| Drive Point Motors Ltd | Wholesale & retail | 2026 |
| Drizi Painting and Decorating Ltd | Construction | 2023 |
| DRK Enterprises Limited | Administrative & support | 2017 |
| Drsami Associates Limited | Other services | 2020 |
| Drumkit Limited | Financial services | 2026 |
| Drylining BG Ltd | Construction | 2017 |
| Drylininngbg Ltd | Construction | 2023 |
| DSA Theatrical Agency Limited | Arts & recreation | 1967 |
| DSC Properti Limited | Real estate | 2024 |
| DSM Projects Limited | Information & communication | 2026 |
| Dums Chauffeur Experience Ltd | Transport & logistics | 2025 |
| Dusted Codes Limited | Information & communication | 2018 |
| Dutch Fine Paintings Ltd | Construction | 2022 |
| Dyno Electronics Ltd | Wholesale & retail | 2025 |
| Dystopian Disco Ltd | Extraterritorial | 2017 |
| E & S Building Construction Ltd | Construction | 2018 |
| E Ecommerce Holding Limited | Wholesale & retail | 2023 |
| E&Fp Holdings Limited | Professional & scientific | 2024 |
| E44 Ltd | Administrative & support | 2012 |
| Eaglenet Limited | Hospitality | 2020 |
| Eala Pearl Ltd | Professional & scientific | 2025 |
| Ealing Barber Limited | Other services | 2015 |
| Eamindset Ltd | Information & communication | 2023 |
| Earley Media Ltd | Information & communication | 2017 |
| Earth Village Project Limited | Professional & scientific | 2009 |
| East African Club 4 Housing (Each) Ltd | Construction | 2022 |
| Eastviz Ltd | Professional & scientific | 2021 |
| Easy Shop and Go Idea Limited | Wholesale & retail | 2023 |
| Easy Step Flooring Store Limited | Wholesale & retail | 2016 |
| Easycraft Limited | Hospitality | 2000 |
| Easyfixes Maintenance Ltd | Construction | 2022 |
| Easyways Removals Ltd | Construction | 2023 |
| EAT Healthy and More UK Ltd | Hospitality | 2019 |