| Emeny News Ltd | Wholesale & retail | 2022 |
| Emerald Brickwork Products Limited | Construction | 2026 |
| Emerald Catering Limited | Hospitality | 2016 |
| Emerald Green Bookkeeping & Business Services Ltd | Professional & scientific | 2025 |
| Emezee Limited | Transport & logistics | 2012 |
| Emily Horrigan Ltd | Financial services | 2022 |
| Emily Kerrison Ltd | Health & social care | 2023 |
| Emily Mortimer Jewellery Ltd. | Manufacturing | 2015 |
| Emily Tyler Photography Ltd | Professional & scientific | 2023 |
| Emilyd Transport Ltd | Transport & logistics | 2017 |
| Emlen Construction Ltd | Construction | 2015 |
| Emlen Investments Ltd | Real estate | 2020 |
| Emlen Properties Ltd | Real estate | 2021 |
| Emlen SA Rentals Ltd | Hospitality | 2019 |
| Emma Crowhurst Limited | Hospitality | 2012 |
| Emma Paul Ltd | Wholesale & retail | 2020 |
| Emma Rose Collingridge Ltd | Arts & recreation | 2024 |
| Emma Wilden Consulting Ltd | Professional & scientific | 2026 |
| Emma's Small World Limited | Health & social care | 2014 |
| Emmaca Transport Limited | Transport & logistics | 2025 |
| Emmanate Properties Limited | Real estate | 2025 |
| Emmanuel OSE Iseghohimen Ltd | Health & social care | 2023 |
| Emmar Group Ltd | Wholesale & retail | 2026 |
| Emmasand Healthcare Ltd | Health & social care | 2021 |
| Emmaus Suffolk Limited | Hospitality | 2008 |
| Emmerson Accountants Limited | Professional & scientific | 2003 |
| Emmerson Properties Limited | Construction | 2014 |
| Emmitt Plant Limited | Administrative & support | 1979 |
| Emotional First AID Limited | Education | 2022 |
| Emotional Support for YOU CIC | Other services | 2018 |
| EMP Drainage Limited | Construction | 2017 |
| EMP Surveys Limited | Other services | 2021 |
| Empire Marketing Ltd | Administrative & support | 2010 |
| Empire Partnership Holdings Limited | Financial services | 2020 |
| Empire Partnership Investments Limited | Real estate | 2020 |
| Empire Partnership Limited | Administrative & support | 2017 |
| Empire Real State Limited | Real estate | 2022 |
| Empire Studio Creation Limited | Professional & scientific | 2023 |
| Empire Style Innovations Limited | Wholesale & retail | 2024 |
| EMPIRE19 Ltd | Wholesale & retail | 2020 |
| Employ Support Ltd | Professional & scientific | 2012 |
| Employment Specialists (East Anglia) Limited | Administrative & support | 2009 |
| Employment Specialists Ltd | Administrative & support | 2007 |
| Empower IT Solutions Ltd | Information & communication | 2014 |
| Empower Recruitment Ltd | Information & communication | 2020 |
| Empowered Sport Leaders Limited | Arts & recreation | 2024 |
| EMR Run Properties Ltd | Real estate | 2020 |
| Emsdens Limited | Professional & scientific | 2010 |
| Emson Carter (Apollo) Ltd | Real estate | 2024 |
| Emson Carter (Eden) Ltd | Real estate | 2025 |
| Emson Carter Ltd | Financial services | 2024 |
| ENA Rail & Electrics Ltd | Construction | 2021 |
| Enable 2 Reable Ltd | Health & social care | 2017 |
| Enable Innovation Ltd | Information & communication | 2010 |
| Enableit Support Limited | Information & communication | 2010 |
| Enableit Technologies Limited | Information & communication | 2002 |
| Enalinks Ltd | Wholesale & retail | 2023 |
| Encann Limited | Construction | 2021 |
| Enchanted Studios Ltd | Information & communication | 2024 |
| Encore Wellness Limited | Real estate | 2016 |
| Encore Wellness Retail Limited | Administrative & support | 2016 |
| Endeavour GBR Limited | Professional & scientific | 2016 |
| Energie Solutions Ltd | Construction | 2012 |
| Energis Power LP | | 2016 |
| Energy Consultants Ltd | Professional & scientific | 2022 |
| Energy CP Invest Ltd | Financial services | 2025 |
| Energy Evaluations and Solutions Ltd | Professional & scientific | 2006 |
| Energy Global Ltd | Construction | 2025 |
| Energy on TAP Limited | Construction | 2011 |
| Energy Properties Limited | Real estate | 2013 |
| Energy Ready Limited | Professional & scientific | 2019 |
| Energy Technical & Commercial Services Ltd | Administrative & support | 2015 |
| Energy Technical & Renewable Services Limited | Administrative & support | 2007 |
| Energy Utility Management Limited | Professional & scientific | 2003 |
| Energybridge (UK) Limited | Professional & scientific | 2017 |
| Engage & Connect Ltd | Administrative & support | 2018 |
| Engagepro Ltd | Information & communication | 2025 |
| Engine Recruitment Ltd | Administrative & support | 2023 |
| Engineroom Design (London) Ltd | Professional & scientific | 2019 |
| Engyne Health Ltd | Health & social care | 2026 |
| Eni-Coward Limited | | 1988 |
| Enicra Ltd | Information & communication | 2024 |
| Enonis Cuisine Ltd | Manufacturing | 2025 |
| ENR Trading Ltd | Wholesale & retail | 2007 |
| Ensemble HR Consulting Ltd | Professional & scientific | 2022 |
| Enso Property Holdings Ltd | Real estate | 2023 |
| Ensol Holdings Ltd | Professional & scientific | 2025 |
| ENT Clinical Services Limited | Health & social care | 2009 |
| ENT Properties Limited | Real estate | 2024 |
| Enterprise Heritage Limited | Construction | 1993 |
| Enterprise Residential Development Limited | Construction | 1994 |
| Enterprise Systems Limited | Information & communication | 2003 |
| Enviro Planet Ltd | Construction | 2021 |
| Envirobins Ltd | Administrative & support | 2016 |
| Enviromistic Ltd | Wholesale & retail | 2020 |
| Environmental Installations (Ipswich) Limited | | 1971 |
| Envirotel Limited | Information & communication | 2020 |
| Envision 2.0 Ltd | Professional & scientific | 2024 |
| Envoza Limited | Information & communication | 2006 |
| EOR Software Ltd | Information & communication | 2021 |