| SB Trans Limited | Construction | 2018 |
| SB Tuning Ltd | Wholesale & retail | 2025 |
| SB Window Glazing & Constructions Ltd | Construction | 2025 |
| SB Xstore Ltd | Wholesale & retail | 2025 |
| Sb.Gardening&Landscaping Ltd | Administrative & support | 2022 |
| SBC Shield Ltd | Administrative & support | 2026 |
| Sbhm Ltd | Health & social care | 2014 |
| SBI Coaching Limited | Professional & scientific | 2014 |
| SBI Media UK Limited | Professional & scientific | 2022 |
| Sbit Services Limited | Information & communication | 2015 |
| SBK Skin & Laser Ltd | Extraterritorial | 2021 |
| Sbnaeg Holding Ltd | Wholesale & retail | 2019 |
| Sbps Solutions Limited | Professional & scientific | 2012 |
| Sbrjs Enterprise Limited | Information & communication | 2013 |
| SBS Wellington Project Ltd | Real estate | 2023 |
| Sbss Care Services Ltd | Health & social care | 2024 |
| Sbss Hospitality Ltd | Hospitality | 2019 |
| Sbss Investments Ltd | Real estate | 2023 |
| Sbudi Couriers Limited | Transport & logistics | 2021 |
| SC Parking Limited | Administrative & support | 2024 |
| SC Properties London Ltd | Real estate | 2025 |
| SC Quantum Ltd | Real estate | 2024 |
| SC Work Construction Ltd | Construction | 2021 |
| SC Work Group Ltd | Construction | 2024 |
| Scale London Limited | Wholesale & retail | 2024 |
| Scale Media International Limited | Information & communication | 2026 |
| Scaleup Accounting Limited | Professional & scientific | 2026 |
| Scan Align Ltd | Health & social care | 2025 |
| Scan Slot Finder Ltd | Information & communication | 2023 |
| Scan Today Ltd | Health & social care | 2026 |
| Scape Lofts Ltd | Construction | 2025 |
| SCC Exeter Super Limited | Wholesale & retail | 2022 |
| Scene-Opsis Productions Limited | Administrative & support | 2025 |
| Scentup Ltd | Wholesale & retail | 2024 |
| Sceon Consulting Ltd | Administrative & support | 2024 |
| Scepter Technologies Ltd | Information & communication | 2019 |
| SCG Care Limited | Wholesale & retail | 2002 |
| SCH Solutions Ltd | Information & communication | 2010 |
| Schlierix Ltd | Education | 2026 |
| Scholar Online UK Ltd | Education | 2020 |
| Scholars Club Limited | Information & communication | 2025 |
| Scholars Power Limited | Water & waste | 2019 |
| Scholastica Academy Ltd | Education | 2021 |
| School of Rock (Holdings) Limited | Education | 2022 |
| School Travel Services Limited | Transport & logistics | 2024 |
| Schuled Educational Services Ltd | Information & communication | 2023 |
| Schwartz Developments Limited | Construction | 2011 |
| Scicom FP Ltd | Wholesale & retail | 2025 |
| Sciebior Brothers Limited | Construction | 2025 |
| Scientia Educational Centre Ltd | Education | 2023 |
| Scientific AGE Research and Testing LAB Ltd | Construction | 2003 |
| Scientific Content Ltd | Professional & scientific | 2025 |
| Scientific Design Ltd | Construction | 2020 |
| Scientific Hospitality Ltd | Education | 2019 |
| Scientific Investments Ltd | Construction | 2025 |
| Scire Capital Investments Ltd | Real estate | 2024 |
| SCL Subcontractors Ltd | Construction | 2024 |
| SCM Concept Ltd | Construction | 2016 |
| SCN Trading Ltd | Wholesale & retail | 2016 |
| Scooper Heroes Ltd | Other services | 2025 |
| Scope Healthcare Consulting Limited | Health & social care | 2005 |
| Scope Media Group Ltd | Manufacturing | 2021 |
| Scope Ventures Limited | Health & social care | 2018 |
| Scorpion Rose Limited | Wholesale & retail | 2015 |
| Scotcart Limited | Wholesale & retail | 2025 |
| Scotish Limited | Wholesale & retail | 2025 |
| Scott-Hire Limited | Transport & logistics | 2002 |
| Scott-Thorne Property Ltd | Real estate | 2020 |
| Scout Facilities Management Ltd | Administrative & support | 2026 |
| Scouting Ventures Limited | Real estate | 2019 |
| SCR Fast Food Ltd | Hospitality | 2024 |
| Scribe Perfect Ltd | Real estate | 2014 |
| Scroll and Co Studio Ltd | Professional & scientific | 2025 |
| Scrubsy Ltd | Administrative & support | 2025 |
| SCS Finance Limited | Construction | 2025 |
| Sculptea Ltd | Wholesale & retail | 2025 |
| SCV SPV 1 Ltd | Real estate | 2017 |
| SD Commercial (UK) Ltd | Real estate | 2014 |
| SD General Construction Ltd | Construction | 2022 |
| SD IT Consulting Services Ltd | Information & communication | 2025 |
| SD Lettings Limited | Real estate | 2025 |
| SD Performance Tuning Ltd | Wholesale & retail | 2025 |
| SD Proconstruction Ltd | Construction | 2025 |
| Sdea Ltd | Financial services | 2014 |
| SDH 1 Ltd | Real estate | 2018 |
| SDH Properties Ltd | Real estate | 2017 |
| Sdkm Basi 31 Ltd | Real estate | 2021 |
| Sdns Consultants Limited | Administrative & support | 2016 |
| SDS Builders Ltd | Construction | 2023 |
| Sdxworx Ltd | Administrative & support | 2020 |
| SE Design Ltd | Wholesale & retail | 2019 |
| Sea Pulse Limited | Transport & logistics | 2026 |
| Seacoders Ltd | Wholesale & retail | 2023 |
| Seads Investments Limited | Real estate | 2017 |
| Seafood Nights Ltd | Wholesale & retail | 2025 |
| Seagull House Ltd | Real estate | 2022 |
| Seal Equipment Auto Limited | Wholesale & retail | 1974 |
| Seamless Advisory Ltd | Professional & scientific | 2023 |
| Seamless UK Technologies Ltd | Professional & scientific | 2025 |
| Sean’S Decorating Solutions Limited | Construction | 2023 |