| Nini’S Store Ltd | Wholesale & retail | 2026 |
| Nirzam Ltd | Hospitality | 2019 |
| NJG Electrical Ltd | Construction | 2023 |
| Njjs Properties Ltd | Real estate | 2025 |
| Njoy Developments Limited | Real estate | 2007 |
| Njoy Property Limited | Construction | 2004 |
| NK Vehicles Ltd | Wholesale & retail | 2021 |
| NMB Consultancy Limited | Professional & scientific | 2025 |
| NO.51 Rentals Limited | Real estate | 2015 |
| Noah's A.R.T. | Health & social care | 2015 |
| Noble Property Ltd | Real estate | 2023 |
| Noir Nook Ltd | Hospitality | 2025 |
| Noori Construction Ltd | Construction | 2026 |
| Nordic Business Experts Ltd | Wholesale & retail | 2024 |
| North Bangladeshi Cricket Association Ltd | Health & social care | 2024 |
| North Safety Limited | Extraterritorial | 2017 |
| North West Autotech Ltd | Wholesale & retail | 2024 |
| North West Historic Graffiti Survey C.I.C. | Professional & scientific | 2017 |
| North West Plumbing Ltd | Construction | 2019 |
| Northcrest Motors Ltd | Wholesale & retail | 2026 |
| Northern Property Consortium Limited | Construction | 2019 |
| Northern School of Hospitality Ltd | Education | 2026 |
| Northern Spirit C.I.C. | Arts & recreation | 2020 |
| Norton Property Services (Manchester) Limited | Real estate | 2023 |
| NOT Just Padel Limited | Arts & recreation | 2025 |
| Nourish Northern Mamas Ltd | Wholesale & retail | 2018 |
| Novinest Ltd | Wholesale & retail | 2025 |
| NPC Management Services Ltd | Other services | 2023 |
| NRB Cheshire Limited | Construction | 2021 |
| NRG Plumbing and Heating Ltd | Construction | 2021 |
| Nubian Royale Ltd | Wholesale & retail | 2018 |
| Nucrete Online Limited | Wholesale & retail | 2026 |
| Numerology Accountants Ltd | Professional & scientific | 2023 |
| Nutri Gains Meal Prep Ltd | Manufacturing | 2019 |
| Nuvora Pulse Ltd | Wholesale & retail | 2025 |
| NWS Quantity Surveying UK Limited | Professional & scientific | 2026 |
| NXT GEN Retail Ltd | Wholesale & retail | 2019 |
| Oak Wood Rooms Ltd | Administrative & support | 2024 |
| Oaklands Hall Company Limited | Administrative & support | 1924 |
| Oasis Personal Credit Limited | Financial services | 2002 |
| Oceros Marketing Ltd | Professional & scientific | 2023 |
| Office Service Bureau Limited | Extraterritorial | 1986 |
| Olcha Properties Limited | Real estate | 2019 |
| Old School Court (Ashton-Under-Lyne) Management Co Ltd | Households | 2006 |
| Old Tannery Management Company (GEE Cross) Limited | Households | 2001 |
| Old Unity LLP | | 2012 |
| Oldham & Company (Accountants) Limited | Professional & scientific | 1998 |
| ON Electrical Contractors & Services Ltd | Construction | 2022 |
| ON Time Design Ltd | Administrative & support | 2019 |
| One Bay Trading Limited | Wholesale & retail | 2020 |
| One Stop Caring Ltd | Health & social care | 2020 |
| One Stop for Safety Limited | Wholesale & retail | 2023 |
| One Thirty Five Ltd | Wholesale & retail | 2024 |
| ONE99 Design Limited | Professional & scientific | 2011 |
| Onebrook Limited | Administrative & support | 2024 |
| Ongo Service Management Limited | Information & communication | 2025 |
| Onward Properties (Hyde) Limited | Real estate | 2021 |
| Onyx Rentals Ltd | Real estate | 2025 |
| Opal Independent School for Education Limited | Education | 2015 |
| Open Path Recruitment Ltd | Other services | 2025 |
| Opened Arms Unique Care Services Limited | Health & social care | 2025 |
| Optiflow Campaigns Ltd | Administrative & support | 2025 |
| Optimum Metals Limited | Professional & scientific | 2016 |
| Orbit Healthcare Limited | Health & social care | 2014 |
| Orcadia Residential Home Limited | Health & social care | 2005 |
| Order Blinds Online Ltd | Administrative & support | 2009 |
| Orient Property Developments Limited | Real estate | 1998 |
| Orientana Ltd | Wholesale & retail | 2021 |
| Orlams Home Ltd | Wholesale & retail | 2026 |
| Orthorevision Ltd | Education | 2023 |
| OS Capital Limited | Other services | 2014 |
| OSG 1983 Ltd | Arts & recreation | 2025 |
| Osum BEE Ltd | Wholesale & retail | 2025 |
| OT Build and Refurbishment Ltd | Construction | 2025 |
| OUR Agency CIC | Health & social care | 2019 |
| Oushk RX Ltd | Wholesale & retail | 2025 |
| Oushk Supplements Ltd | Health & social care | 2025 |
| OUT in Front Consultants Limited | Manufacturing | 2013 |
| Out-Of-Order Ltd | Wholesale & retail | 2025 |
| Outsource Systems Limited | Information & communication | 2005 |
| Outsourced Services LLP | | 2014 |
| Overdale (GEE Cross) RTM Company Limited | Households | 2021 |
| OVO Investi Limited | Construction | 2017 |
| Owens Business Services Ltd | Professional & scientific | 2025 |
| Oxby's Flooring Limited | Construction | 2014 |
| P & B Property Manchester Ltd | Real estate | 2023 |
| P & H Lawnmowers Limited | Wholesale & retail | 2014 |
| P & J Investments Limited | Real estate | 1999 |
| P Architects Ltd | Professional & scientific | 2026 |
| P G Fabrications Limited | Manufacturing | 2004 |
| P J W Building & Electrical Services Limited | Administrative & support | 2013 |
| P K W Cookies Limited | Wholesale & retail | 2010 |
| P K W Foods Limited | Hospitality | 2005 |
| P S W Property Developers Ltd | Real estate | 2010 |
| P&L Financial Solutions Ltd | Financial services | 2025 |
| P&M Lettings Ltd | Households | 2012 |
| P. & J. Roberts Limited | Manufacturing | 1985 |
| P.H. Insulations Limited | Construction | 1998 |
| P.R.E.A. Ltd | Administrative & support | 1996 |
| P24V1 Limited | Real estate | 2026 |