| DC Travel Representation Limited | Administrative & support | 2018 |
| DC Turnkey Ltd | Real estate | 2023 |
| DCD Consulting Ltd | Information & communication | 2018 |
| DCF Consultants Ltd | Professional & scientific | 2019 |
| DCLOUD9 Ltd | Information & communication | 2013 |
| Dcmd Ltd | Administrative & support | 2003 |
| DDS (Digital Direct Security) Ltd | Administrative & support | 2005 |
| DE Silva Healthcare Ltd | Health & social care | 2026 |
| Dean Packaging Limited | Manufacturing | 2000 |
| Dean Yacht Management Limited | Other services | 2004 |
| Deans Roofing Ltd | Construction | 2025 |
| Deavesons Limited | Wholesale & retail | 2009 |
| Decluttair Limited | Manufacturing | 2015 |
| Decoris Furniture Ltd. | Construction | 2014 |
| Dedalus Limited | Information & communication | 1983 |
| Deeho Limited | Information & communication | 2008 |
| Deemash Limited | Health & social care | 2025 |
| Deep Talent Ltd | Administrative & support | 2025 |
| Deeprose Investments Limited | Wholesale & retail | 2023 |
| Deerwise Ltd | Agriculture & fishing | 2026 |
| Deft Property Solutions Limited | Construction | 2016 |
| Deks Consulting Limited | Professional & scientific | 2015 |
| Delivery Management Ltd | Professional & scientific | 2004 |
| Delta Doors Ltd | Construction | 2021 |
| Deming Alliance Ltd | Other services | 2019 |
| Denatrol Ltd | Manufacturing | 2013 |
| Denisa Transport Ltd | Transport & logistics | 2022 |
| Dentafix UK Ltd | Wholesale & retail | 2023 |
| Dental Direct UK Ltd | Wholesale & retail | 2009 |
| Denteka Ltd | Health & social care | 2013 |
| Denver Supply Ltd | Wholesale & retail | 2025 |
| Dep-Dec Decorators Ltd | Construction | 2015 |
| Derbyshire Consultancy Limited | Professional & scientific | 2014 |
| Dermacure Clinic Limited | Other services | 2025 |
| Desiderate Ltd | Wholesale & retail | 2021 |
| Design Eden Ltd | Professional & scientific | 2021 |
| Design Inspirations Limited | Professional & scientific | 2005 |
| DESIGN27 Ltd | Professional & scientific | 2021 |
| Designed for Success (Distribution) Limited | Wholesale & retail | 2010 |
| Desire 2 Study Ltd | Education | 2020 |
| Dewey School of Dance Limited | Arts & recreation | 2019 |
| DFS Business Services Limited | Professional & scientific | 2026 |
| DFS Group Limited | Professional & scientific | 2012 |
| Dfsmarketplace Limited | Wholesale & retail | 2010 |
| DGE Electrical Services Limited | Construction | 2021 |
| DGL Venues Limited | Hospitality | 2015 |
| DHK Holdings INT Ltd | Financial services | 2022 |
| DHM Plastics Limited | Extraterritorial | 1955 |
| Dhollandia U.K. Limited | Manufacturing | 1995 |
| Dhollandia UK Production Ltd | Manufacturing | 2022 |
| Diagval Ltd | Information & communication | 2025 |
| Diamond D Services Ltd | Construction | 2023 |
| Diamond Ground Products Limited | Manufacturing | 2000 |
| Diamond Hampers CIC | Hospitality | 2020 |
| Digio Limited | Information & communication | 1995 |
| Digitalcreate Limited | Information & communication | 2021 |
| Dignifex Ltd | Information & communication | 2020 |
| Dilawarecomm Ltd | Wholesale & retail | 2025 |
| Dimma Consult Ltd | Professional & scientific | 2025 |
| Dining at the Jolly Ltd | Hospitality | 2024 |
| Dinosaur Bytes Studio Ltd | Arts & recreation | 2018 |
| Dionysus Holdings Limited | Other services | 2017 |
| Direct 2 Site (UK) Limited | Wholesale & retail | 2006 |
| Direct Communications Radio Services Limited | Other services | 1987 |
| Direct Communications Shopwatch Limited | Professional & scientific | 1990 |
| Direct Door Solutions Herts Ltd | Construction | 2015 |
| Direct Heating Parts (Peterborough) Limited | Wholesale & retail | 1994 |
| Dirzysm Transport Ltd | Wholesale & retail | 2016 |
| Disarray Ltd | Wholesale & retail | 2017 |
| Discern Group Limited | Information & communication | 2024 |
| Discipleship Insight CIC | Professional & scientific | 2025 |
| Discount Tiles Direct Limited | Extraterritorial | 1998 |
| Discover ST Neots Ltd | Administrative & support | 2025 |
| Dishley Farming Limited | Agriculture & fishing | 2008 |
| Distill Bar Ltd | Hospitality | 2026 |
| Distribution Supplies Group Limited | Wholesale & retail | 2014 |
| Distribution Supplies Limited | Wholesale & retail | 1994 |
| Dixie Trans Ltd | Transport & logistics | 2019 |
| Dixon Building Solutions Ltd | Construction | 2018 |
| DJ Agri Plant Limited | Administrative & support | 2025 |
| DJM Composites Ltd | Manufacturing | 2025 |
| Dkhaulage Limited | Transport & logistics | 2024 |
| DLM Drylining Ltd | Construction | 2021 |
| DMC Admin Limited | Construction | 2010 |
| DMF Electrical & Property Services Ltd | Construction | 2026 |
| Dmgp Holdings Limited | Professional & scientific | 2010 |
| DMT Infinity Ltd | Wholesale & retail | 2025 |
| DMW Media Ltd | Information & communication | 2026 |
| DN Company Service Ltd | Wholesale & retail | 2016 |
| DNA Event Security Ltd | Administrative & support | 2025 |
| DNA Motivation Limited | Other services | 2017 |
| DNA Security Solutions Ltd | Administrative & support | 2024 |
| DNR Property & Investment Ltd | Real estate | 2026 |
| Docnova Ltd | Wholesale & retail | 2025 |
| Doctor Aneela Limited | Health & social care | 2022 |
| Doculytics Ltd | Information & communication | 2025 |
| Documents Online Limited | Information & communication | 2011 |
| Doherty Energy Limited | Professional & scientific | 2007 |
| Dolby & Clarke Ltd | Financial services | 2016 |
| Dolby & Clarke Properties Limited | Hospitality | 2017 |