| Flynn Joinery Contractors Limited | Construction | 2016 |
| FM + Limited | Administrative & support | 2016 |
| Fmbusinessdaily.Com Limited | Administrative & support | 2019 |
| FNP Limited | Construction | 2011 |
| FO Sports Limited | Arts & recreation | 2023 |
| Foam Concrete Machines Ltd | Construction | 2023 |
| Fobe Healthcare Ltd | Health & social care | 2022 |
| Fobet Education and Training Ltd | Education | 2021 |
| Focus Compliance Ltd | Hospitality | 2022 |
| Focus Counselling Services (Hull) Limited | Health & social care | 2002 |
| Focus Counselling Services Limited | Health & social care | 2022 |
| Focus D.I.Y. Direct Limited | Extraterritorial | 2011 |
| Focus Education and Training Limited | Education | 2012 |
| Focus Talking Therapies Limited | Health & social care | 2024 |
| Focus Wellbeing Services Limited | Health & social care | 2020 |
| Fold Yard Self Storage Ltd | Administrative & support | 2025 |
| Folie Chambre Limited | Wholesale & retail | 2023 |
| Foluscouture Ltd | Wholesale & retail | 2025 |
| Foncall Ltd | Professional & scientific | 2014 |
| FONEWORLD4UK Ltd | Wholesale & retail | 2021 |
| Fonfon Consulting Limited | Professional & scientific | 2019 |
| Food Express Hull Ltd | Hospitality | 2025 |
| Food Express North Ltd | Wholesale & retail | 2026 |
| Food for Cowboys Ltd | Hospitality | 2023 |
| Food Simply Sorted Limited | Wholesale & retail | 2025 |
| Food Supplies U.K. Limited | Wholesale & retail | 2012 |
| Foodfix Africana Ltd | Hospitality | 2025 |
| Foody's ULL' Ltd | Hospitality | 2024 |
| Football Encounters UK Ltd | Administrative & support | 2002 |
| Footie Archives Ltd | Wholesale & retail | 2025 |
| FOR ME to Love Ltd | Wholesale & retail | 2014 |
| Forbes Blythe Property Holdings Ltd | Real estate | 2026 |
| Ford Asphalte (Hull) Limited | Construction | 2019 |
| Ford Specialists Limited | Wholesale & retail | 2025 |
| Ford-Hall Properties Ltd | Real estate | 2026 |
| Forensic Response UK CIC | Other services | 2024 |
| Fores Electrical Ltd | Construction | 2025 |
| Forest & Fire Ltd | Professional & scientific | 2025 |
| Forest Timber Products Ltd | Wholesale & retail | 2026 |
| Forever Young Aesthetics Ltd | Other services | 2022 |
| Forezon Consultants Ltd | Financial services | 2019 |
| Forge Holdings Limited | Water & waste | 1991 |
| Fork Handles Holdings Limited | Wholesale & retail | 2019 |
| Form North Limited | Wholesale & retail | 2017 |
| Formeda Limited | Financial services | 2013 |
| Forrest & Co Limited | Hospitality | 2018 |
| Forrester Design Ltd | Professional & scientific | 2017 |
| Forster Media Ltd | Information & communication | 2017 |
| Fort Paull Ltd | Hospitality | 2024 |
| Fortifire Fire and Safety Limited | Professional & scientific | 2019 |
| Fortis Leisure Homes Ltd | Wholesale & retail | 2016 |
| Fortrace Limited | Manufacturing | 1990 |
| Fortuna Collectibles Limited | Wholesale & retail | 2026 |
| Fortuna Numismatics Limited | Wholesale & retail | 2022 |
| Forty Acre Plumbing & Heating Limited | Construction | 2008 |
| Forty Property Ltd | Real estate | 2020 |
| Forward Asset Holdings Limited | Financial services | 2023 |
| Forward Contracting (UK) Limited | Construction | 2012 |
| Forward Initiative CIC | Hospitality | 2024 |
| Forward Motor Finance Ltd | Financial services | 2021 |
| Forward Pest & Hygiene Limited | Administrative & support | 2022 |
| FOS Hull Limited | Arts & recreation | 2026 |
| Four Reasons Training Academy Limited | Education | 2025 |
| Four Seasons 1 Ltd | Wholesale & retail | 2023 |
| Four Seasons Landscaping by Mike Naylor Ltd | Administrative & support | 2012 |
| FOUR3 Ltd | Administrative & support | 2018 |
| Fourix Ltd | Wholesale & retail | 2025 |
| Fowler Engineering Services Ltd | Construction | 2023 |
| FOX Consultanting Ltd | Professional & scientific | 2025 |
| FOX Holdings Lincolnshire Limited | Financial services | 2022 |
| FOX Industrial & Engineering Supplies Ltd | Wholesale & retail | 2016 |
| FOX Precision Engineering Ltd | Manufacturing | 2003 |
| Fox's Fold Management Company Limited | Households | 2014 |
| Foxglove Bespoke Care and Support Services Limited | Health & social care | 2018 |
| Foxglove Care Limited | Health & social care | 2003 |
| Foxglove Interactive Limited | Information & communication | 2026 |
| Foxglove Supported Living Limited | Health & social care | 2015 |
| Foxwell Developments (ENG) Limited | Real estate | 2025 |
| Foxy Vehicle Rentals Ltd | Administrative & support | 2019 |
| FPS Tech Ltd | Other services | 2020 |
| FPS UK Asset Realisations Ltd | Professional & scientific | 2013 |
| Frabemar (UK) Limited | Wholesale & retail | 2011 |
| Fractal Software Limited | Information & communication | 2015 |
| Frais DE Mariage Limited | Hospitality | 2025 |
| Frame & Finish Limited | Other services | 2024 |
| Francesco Restaurant Ltd | Hospitality | 2018 |
| Francis Court Management (Hull) Limited | Real estate | 2006 |
| Frank Hill & SON (Architectural Services) Limited | Professional & scientific | 2005 |
| Frank Hill & SON (Auctioneers & Valuers) Limited | Administrative & support | 1982 |
| Franklin Apartments Management Company Ltd | Administrative & support | 2007 |
| Franklin Watt Consultancy Services Limited | Professional & scientific | 2005 |
| Frantz Gregory & Co Ltd | Professional & scientific | 2017 |
| Fraser Accident Repairs Limited | Wholesale & retail | 2003 |
| Fraser Structural Engineer Services Ltd | Professional & scientific | 2023 |
| FRE Shop Fashion Ltd | Wholesale & retail | 2024 |
| Fred Marketing Limited | Administrative & support | 2007 |
| Freedom Festival Arts Trust | Arts & recreation | 2013 |
| Freedom Road Creative Arts | Arts & recreation | 2008 |
| Freelancimals Ltd | Wholesale & retail | 2025 |
| Freemova Education Ltd | Education | 2025 |