| DDR - DAS OCH LLP | | 2015 |
| DDV Property Services Ltd | Construction | 2026 |
| DE Havenlynk Limited | Wholesale & retail | 2025 |
| De&H Ltd | Manufacturing | 2023 |
| Dead BOD Property Limited | Real estate | 2020 |
| Deadline Industries Limited | Construction | 2016 |
| Dealzee Ltd | Wholesale & retail | 2025 |
| Deano Media Ltd | Wholesale & retail | 2023 |
| Deans Marina & Services Ltd | Other services | 2022 |
| Dean`S Holdings Limited | Real estate | 2008 |
| Dearlove Investments (Holdings) Limited | Financial services | 2026 |
| Debbie Wilkinson Photography Limited | Professional & scientific | 2003 |
| Debinat Global Services Ltd | Construction | 2024 |
| Debrajayne Ltd | Real estate | 2025 |
| Decision Consultant Solutions Ltd | Information & communication | 2019 |
| Decoplum Limited | Construction | 2018 |
| Decor Global Cleaning Ltd | Administrative & support | 2021 |
| Decorating Rates Limited | Information & communication | 2025 |
| Deep Sea Line Ltd | Transport & logistics | 1996 |
| Deep Tech Nano Zets Limited | Professional & scientific | 2026 |
| Deeside Power (UK) Limited | Professional & scientific | 2014 |
| Deeside Power Operations Limited | Energy | 2020 |
| Deez Pastries Limited | Manufacturing | 2025 |
| Dee’S Delights and Events Limited | Hospitality | 2021 |
| DEL Accountancy and Tax Support Limited | Professional & scientific | 2013 |
| DEL Bookkeeping and Payroll Services Limited | Professional & scientific | 2015 |
| Delapole (Hull ) Ltd | Hospitality | 2026 |
| Delct Limited | Health & social care | 2018 |
| Deli-Licious Willerby Ltd | Hospitality | 2017 |
| Deliciously Crafty Ltd | Hospitality | 2019 |
| Delight Consulting Ltd | Professional & scientific | 2025 |
| Delight Salads Limited | Agriculture & fishing | 2016 |
| Delighted Property Ltd | Real estate | 2024 |
| Della Peruta Vincenzo UK Ltd | Wholesale & retail | 2019 |
| Della Terra (Hull) Limited | Hospitality | 2025 |
| Delt Furniture Installations Ltd | Construction | 2004 |
| Delta Overseas Ltd | Wholesale & retail | 2024 |
| Delta Security Networks Ltd | Other services | 2024 |
| Delta Security Properties Limited | Real estate | 2018 |
| Deluxe Doggy Daycare Limited | Agriculture & fishing | 2025 |
| Deluxe Landscapes Ltd | Administrative & support | 2023 |
| Demopro Marine Limited | Construction | 2020 |
| DEN Hartogh DRY Bulk Logistics Limited | Transport & logistics | 1981 |
| DEN Interior Limited | Professional & scientific | 2018 |
| DEN Roofing Limited | Construction | 2021 |
| Dene Park Holdings Ltd | Real estate | 2005 |
| Denise's Pantry Ltd | Hospitality | 2024 |
| Denm Limited | Professional & scientific | 2021 |
| Denness Properties Ltd | Real estate | 2025 |
| Dennis Butler Limited | Wholesale & retail | 1982 |
| Dennis's Ices Ltd | Wholesale & retail | 2025 |
| Dennison Engineering Ltd | Professional & scientific | 2023 |
| Dental Logic Limited | Health & social care | 2017 |
| Dentequip Solutions Ltd | Manufacturing | 2025 |
| Denton Hughes Ltd | Administrative & support | 2022 |
| Dents OUT (Yorkshire) Ltd | Wholesale & retail | 2018 |
| Deny Transport Limited | Manufacturing | 2018 |
| Depheels Global Services Limited | Real estate | 2024 |
| Derek Construction Ltd | Construction | 2014 |
| Dereli Property Limited | Real estate | 2024 |
| Derik Properties Limited | Real estate | 2021 |
| Dervey Developments Limited | Real estate | 2019 |
| Desert Rose AHA Limited | Wholesale & retail | 2024 |
| Desi Curry Ltd | Hospitality | 2024 |
| Design Investment Build Ltd | Real estate | 2000 |
| Design Sign Manufacturing Ltd | Manufacturing | 2020 |
| Design Sign UK Ltd | Manufacturing | 2023 |
| Design Workshop (Humberside) Holdings Limited | Financial services | 2011 |
| Design Workshop (Humberside) Limited | Professional & scientific | 1984 |
| Designer Gents Limited | Other services | 2010 |
| Designer Gentz Limited | Other services | 2012 |
| Designer Hair and Beauti Ltd | Other services | 2017 |
| Designs Signage Solutions Limited | Manufacturing | 2003 |
| Desr Limited | Wholesale & retail | 2025 |
| Deuta Limited | Administrative & support | 2025 |
| Develappz (Hull) Limited | Information & communication | 2012 |
| DEVELOPERS2 Ltd | Real estate | 2019 |
| Development Duex Ltd | Construction | 2014 |
| Development One Limited | Construction | 2013 |
| Devine Engineering Ltd | Wholesale & retail | 2014 |
| Devine Marketing Limited | Wholesale & retail | 2018 |
| Devon West Plumbing Limited | Construction | 2025 |
| Devsticks Ltd | Wholesale & retail | 2025 |
| DEW Home Staging Limited | Other services | 2026 |
| Df-Cad Limited | Manufacturing | 2013 |
| Dfch Limited | Administrative & support | 2004 |
| Dfdc Finance Limited | Real estate | 2024 |
| DFG Support Ltd | Professional & scientific | 2026 |
| DFT Tradings Ltd | Manufacturing | 2026 |
| DFW Hull Ltd | Wholesale & retail | 2025 |
| DG Building Refurbishment Ltd | Construction | 2019 |
| DG Trans Ltd | Transport & logistics | 2025 |
| DGH Blade Repairs Ltd | Manufacturing | 2019 |
| DGR Instruments Limited | Manufacturing | 2024 |
| Dgrg Wind Ltd | Manufacturing | 2025 |
| Dhaliwal Properties Hull Limited | Real estate | 2020 |
| Dharma Larma Bars Ltd | Hospitality | 2019 |
| Dharmaratna Buddhist Centre | Other services | 2002 |
| Dhesi Property Ltd | Real estate | 2025 |
| DHG Property Limited | Real estate | 2026 |