| UK Climbing Trustee Limited | Professional & scientific | 2023 |
| UK Curtain Walling Limited | Construction | 2016 |
| UK Dental Ltd | Health & social care | 2023 |
| UK Energy Management Ltd | Construction | 2025 |
| UK Fastflow Limited | Construction | 2015 |
| UK Fire and Electrical Solutions Ltd | Energy | 2016 |
| UK Fire Products Limited | Extraterritorial | 2022 |
| UK Freehold Ltd | Real estate | 2011 |
| UK Furniture Bank Ltd | Health & social care | 2019 |
| UK Future Education Group Limited | Education | 2021 |
| UK Future Events Limited | Education | 2021 |
| UK Geologik Ltd | Administrative & support | 2016 |
| UK Homes Limited | Professional & scientific | 2015 |
| UK Medico Ltd | Health & social care | 2023 |
| UK Owens Properties Ltd | Real estate | 2019 |
| UK Signage Group Limited | Professional & scientific | 2021 |
| UK Skin Professionals LLP | | 2022 |
| UK Traders 110 Limited | Other services | 2025 |
| UK Watch World Ltd | Wholesale & retail | 2019 |
| Uk-China Education & Cultural Exchange Association | Health & social care | 2025 |
| Uk-European Center for Chinese Medicine and Natural Compounds Academy of Biology Ltd | Health & social care | 2024 |
| Ukimporter Ltd | Wholesale & retail | 2023 |
| UKL Health Limited | Health & social care | 2016 |
| Ukvs Corporation Ltd | Professional & scientific | 2023 |
| Ultimate Sport Project CIC | Administrative & support | 2017 |
| Ultimate Wetrooms Limited | Construction | 2018 |
| Ultra Tax Limited | Extraterritorial | 2025 |
| Umami Atlas Limited | Manufacturing | 2016 |
| Umami Cartel Ltd | Hospitality | 2025 |
| Umbra Systems Limited | Information & communication | 2023 |
| Umbrella Yoga CIC | Education | 2020 |
| UMC Healthcare Ltd | Health & social care | 2019 |
| Umeedia Limited | Administrative & support | 2025 |
| Umha Limited | Hospitality | 2024 |
| Umrah Supermarket Huddersfield Ltd | Wholesale & retail | 2023 |
| Umrih Consulting Limited | Health & social care | 2026 |
| Unbeastable Dominion Ltd | Wholesale & retail | 2026 |
| Uncaged Developments Limited | Construction | 2002 |
| Uncharted Ltd | Professional & scientific | 2011 |
| Under PAR Golf Academy Ltd | Education | 2024 |
| Under the Mast Ltd | Manufacturing | 2020 |
| Underpin Health Ltd | Wholesale & retail | 2025 |
| Underpin Sports Limited | Arts & recreation | 2018 |
| Unees Properties UK Ltd | Real estate | 2025 |
| Unescapable Ltd | Arts & recreation | 2018 |
| UNG Private Ltd | Wholesale & retail | 2025 |
| Uniboard Panels Ltd | Manufacturing | 2023 |
| Unibridge EDU Ltd | Education | 2025 |
| Unico Concepts Limited | Hospitality | 2025 |
| Unified Events U.K Ltd | Wholesale & retail | 2018 |
| Unified FM Limited | Information & communication | 2021 |
| Unik Ventures HD1 Ltd | Hospitality | 2026 |
| Unik Ventures Ltd | Hospitality | 2018 |
| Union Plumbing & Heating Limited | Construction | 2014 |
| Union Street Technologies Ltd | Wholesale & retail | 2026 |
| Uniq Pharma Ltd | Professional & scientific | 2010 |
| Unique Accident Repair Centre Ltd | Wholesale & retail | 2026 |
| Unique Cars Huddersfield Limited | Transport & logistics | 2026 |
| Unique Persian Food Ltd | Hospitality | 2019 |
| Unique Projects North Ltd | Construction | 2025 |
| Unique Rays Trading Ltd | Wholesale & retail | 2021 |
| Unit 2 Self Storage Ltd | Administrative & support | 2021 |
| Unit 2 ST James Business Park Limited | Real estate | 2025 |
| Unit 4 Recovery Ltd | Transport & logistics | 2025 |
| Unite Designs Limited | Professional & scientific | 2021 |
| Unite to Care Limited | Other services | 2017 |
| United Anodisers Holdings Limited | Professional & scientific | 2006 |
| United Anodisers Limited | Manufacturing | 2001 |
| United Bathrooms & Tiling Ltd | Construction | 2022 |
| United Group of Industries Ltd | Wholesale & retail | 2023 |
| United K Auto Limited | Wholesale & retail | 2017 |
| United Live Ltd | Other services | 2024 |
| Unitrucks Huddersfield Ltd | Manufacturing | 2020 |
| Unity Shows Ltd | Administrative & support | 2023 |
| Unity Youth Living Ltd | Health & social care | 2026 |
| Universal Car Parts Warehouse Limited | Wholesale & retail | 2009 |
| Universal Halal Authority Limited | Hospitality | 2024 |
| Universal Immigration Services Ltd | Professional & scientific | 2024 |
| Universal Motors UK Limited | Wholesale & retail | 1992 |
| Universal Products (UK) Ltd | Health & social care | 2010 |
| Universal Safe Ltd | Wholesale & retail | 2025 |
| Universal Staffing Solutions Limited | Administrative & support | 2018 |
| Universal Waterproofing Products Limited | Professional & scientific | 2001 |
| University of Huddersfield Students' Union | Other services | 2021 |
| Unlock Finance Management Limited | Professional & scientific | 2016 |
| Unodostres Limited | Wholesale & retail | 2018 |
| Unrooted Drinks Limited | Extraterritorial | 2021 |
| Untap Project C.I.C. | Information & communication | 2021 |
| Uohvo Limited | Wholesale & retail | 2022 |
| UP and Above Scaffolding Ltd | Construction | 2022 |
| UP North Estates Ltd | Real estate | 2024 |
| UP2SPEED Ltd | Transport & logistics | 2020 |
| UP2UNI Community Interest Company | Education | 2011 |
| Upgraded I.T. Limited | Information & communication | 2018 |
| Uppal Property (Yorkshire) Limited | Real estate | 2018 |
| Upper Denby D C Limited | Health & social care | 2007 |
| Upper Hand Ltd | Education | 2024 |
| Upper House Estate Ltd | Extraterritorial | 2025 |
| Upperwood Tree and Landscaping Services Ltd | Administrative & support | 2021 |
| Upside Financial Technologies and Consultancy Ltd | Information & communication | 2019 |