| Universal Migration Limited | Information & communication | 2024 |
| Universal TRAINING1 Ltd | Information & communication | 2022 |
| Universities Safety and Health Association Limited | Administrative & support | 2015 |
| Unmanned Publications Ltd | Information & communication | 2019 |
| Untamed Skin Ltd | Other services | 2025 |
| Unvrs AI Technologies Ltd | Information & communication | 2025 |
| UOR Consultancy Limited | Information & communication | 2016 |
| Upbridge Ltd | Information & communication | 2024 |
| Upcy Ltd | Information & communication | 2022 |
| Upgrade Two Ltd | Wholesale & retail | 2016 |
| Uplands (Freehold) Management Company Limited | Households | 2009 |
| Upper North Street Ltd | Households | 2025 |
| Upper Rock Gardens Property Ltd | Real estate | 2024 |
| Upper Rock Rooms Ltd | Hospitality | 2018 |
| Upper Wick Solar Limited | Energy | 2013 |
| Upperton Investment Ltd | Real estate | 2022 |
| Upstart Crow Limited | Arts & recreation | 2008 |
| Urban & East Anglia Properties Limited | Real estate | 1961 |
| Urban Advisers Ltd | Real estate | 2021 |
| Urban Drive Ltd | Wholesale & retail | 2025 |
| Urban Serenity Group Limited | Professional & scientific | 2021 |
| Urgent Optimist Limited | Information & communication | 2020 |
| Uroduke Ltd | Wholesale & retail | 2025 |
| UTA Holdings Ltd | Financial services | 2016 |
| Utility Cover Ltd | Information & communication | 2018 |
| Utopia Services Limited | Real estate | 1999 |
| UX Analytic Limited | Information & communication | 2025 |
| Uzga Ltd | Construction | 2024 |
| V Pearce Consulting and Associates Ltd | Professional & scientific | 2012 |
| V&R Commerce Ltd | Wholesale & retail | 2025 |
| V1 Group Ltd | Extraterritorial | 2023 |
| V2 Radio Ltd | Information & communication | 2020 |
| V8FIT Limited | Other services | 2022 |
| Vacat Ltd | Wholesale & retail | 2025 |
| Vail Creative Ltd | Professional & scientific | 2025 |
| Vail Plumbing & Heating Ltd | Construction | 2013 |
| Valangel Limited | Administrative & support | 2015 |
| Vale 1973 Limited | Extraterritorial | 2013 |
| Vale Property Solutions Limited | Construction | 2012 |
| Valelink Limited | Wholesale & retail | 1970 |
| Valentine Carter Ltd | Information & communication | 2017 |
| Valentine Court (Hove) Limited | Households | 2012 |
| Valinch Limited | Arts & recreation | 2005 |
| Valkyrie Diving & Fleet Services Limited | Extraterritorial | 2012 |
| Vallance Court Management Limited | Households | 1981 |
| Vallance Gardens Limited | Households | 2012 |
| Vallance Organisation Limited | Health & social care | 1997 |
| Van Klaveren Consulting Ltd | Professional & scientific | 2023 |
| Vanguard Fire Protection Ltd | Public administration | 2024 |
| Vanguard International Lease Assure Holdings Ltd | Real estate | 2026 |
| Vanilla & Co London Ltd | Wholesale & retail | 2014 |
| Vanix LLP | | 2009 |
| Vantagepoint International Limited | Professional & scientific | 2023 |
| Vanventures Sussex Ltd | Administrative & support | 2025 |
| VAP Market Ltd | Wholesale & retail | 2025 |
| Vape Express (Brighton) Ltd | Wholesale & retail | 2018 |
| Vape Portslade Ltd | Wholesale & retail | 2026 |
| Vape Shop Portslade Ltd | Wholesale & retail | 2024 |
| Vapors Ltd. | Wholesale & retail | 2014 |
| Varahi One Ltd | Professional & scientific | 2026 |
| Varberg Investments Ltd | Real estate | 2025 |
| Varto Properties Limited | Real estate | 2020 |
| VDG Express Couriers 24/7 Ltd | Transport & logistics | 2018 |
| Vector Accounting Software Limited | Information & communication | 2026 |
| Vector Digital Partners Ltd | Professional & scientific | 2026 |
| Vector Medical Limited | Health & social care | 2022 |
| VEE MAJ Care Limited | Health & social care | 2025 |
| VEG Global Limited | Arts & recreation | 2002 |
| Vega Express Ltd | Wholesale & retail | 2020 |
| Velvet Property Limited | Real estate | 2021 |
| Venci Painter and Decorators Ltd | Administrative & support | 2016 |
| Vendbnb Limited | Wholesale & retail | 2026 |
| Vendition Limited | Administrative & support | 2011 |
| Vendmist Limited | Wholesale & retail | 2025 |
| Veni Vidi Vincey Ltd | Professional & scientific | 2026 |
| Venku Ltd | Wholesale & retail | 2023 |
| Venn Audio Limited | Information & communication | 2023 |
| Venture Sports Media UK Ltd | Information & communication | 2020 |
| Venus Cafe Ltd | Hospitality | 2018 |
| Venus Money Limited | Administrative & support | 2012 |
| Veow Limited | Wholesale & retail | 2020 |
| Verano Fragrance Ltd | Other services | 2020 |
| Verba Ltd | Information & communication | 2025 |
| Verband Consulting Ltd | Professional & scientific | 2021 |
| Vergonomics Ltd | Extraterritorial | 2020 |
| Verisure Recruitment Ltd | Administrative & support | 2019 |
| Verner House Residents Association Limited | Households | 2000 |
| Vernon Gardens Management Company Limited | Households | 2006 |
| Vertue Dental Group Limited | Health & social care | 2020 |
| Vervacity Limited | Hospitality | 2006 |
| Very Good Ltd | Information & communication | 2011 |
| Very Serious Comedy Ltd | Arts & recreation | 2019 |
| Very Smart Ltd | Construction | 2015 |
| Very Tall Limited | Information & communication | 2015 |
| Vettedlocal Ltd | Professional & scientific | 2025 |
| Vevor Smart Limited | Wholesale & retail | 2024 |
| VEY Media Limited | Professional & scientific | 2023 |
| VG Construct Limited | Construction | 2024 |
| VG SPV1 Ltd | Financial services | 2025 |
| VG SPV2 Ltd | Financial services | 2025 |