| Physio 1 to 1 Limited | Health & social care | 2013 |
| Piccante Property Limited | Real estate | 2025 |
| Picnic Brighton Ltd | Professional & scientific | 2025 |
| Picture Book Entertainment Limited | Information & communication | 2011 |
| Pictus Productions Limited | Information & communication | 2006 |
| PIE O My Ltd | Hospitality | 2025 |
| PIE Productions Limited | Information & communication | 2022 |
| Pier Property Ltd | Construction | 2014 |
| Pier RD Ltd | Construction | 2019 |
| Pietro Addis & Sons Limited | Hospitality | 1967 |
| Pigeon Talks Limited | Arts & recreation | 2025 |
| Pigs N Flowers Ltd | Hospitality | 2015 |
| Pillar Health Advisory Ltd | Financial services | 2025 |
| Pillars Property UK Ltd | Real estate | 2022 |
| Pillow Property Ltd | Real estate | 2016 |
| Pimperne Projects Ltd | Professional & scientific | 2018 |
| Pindrop Hearing Limited | Wholesale & retail | 2006 |
| Pindy Consulting Ltd | Information & communication | 2025 |
| Pinloma Consulting LLP | | 2010 |
| Pinloma Limited | Real estate | 2009 |
| Pinnacle Events Ltd | Administrative & support | 2025 |
| Pinnacle Lighting Productions Ltd | Other services | 2009 |
| PIP Global Safety Holding UK Limited | Financial services | 2023 |
| Pipsqueak Properties Ltd | Real estate | 2020 |
| Piranhas Ltd | Administrative & support | 2018 |
| Pires Properties Ltd | Real estate | 2026 |
| Pirolli Investments Limited | Households | 2025 |
| Pista Ltd | Extraterritorial | 2015 |
| Pita Parcel Limited | Hospitality | 2016 |
| Pitch Frame Ltd | Professional & scientific | 2025 |
| Pivot Point Physio Ltd | Health & social care | 2025 |
| Pixel Alchemy Ltd | Information & communication | 2017 |
| Pixie's Cuts Ltd | Other services | 2019 |
| Pizza History Ltd | Hospitality | 2022 |
| PJ Property Assets Limited | Real estate | 2019 |
| PK Financial Planning LLP | | 2002 |
| PK Holdings (Sussex) Limited | Professional & scientific | 2013 |
| PK Research Consultancy Limited | Professional & scientific | 2002 |
| PK Wealth Limited | Financial services | 2014 |
| PKP Dental Limited | Health & social care | 2019 |
| Place Farm Solar Limited | Energy | 2012 |
| Place Post Ltd | Professional & scientific | 2016 |
| Plan Ripple Limited | Information & communication | 2025 |
| Planet Properties Limited | Real estate | 1989 |
| Planning One Limited | Information & communication | 2024 |
| Plano Logic Ltd | Administrative & support | 2017 |
| Plant Associates Ltd | Real estate | 2018 |
| Plasmatrack Rail Technology Limited | Professional & scientific | 2024 |
| Platform Nine 2025 Ltd | Real estate | 2024 |
| Platinum Decor Contractors Ltd | Construction | 2017 |
| Play Time Sussex Ltd | Arts & recreation | 2018 |
| Playball Brighton and Hove Ltd | Arts & recreation | 2013 |
| Playhood Limited | Administrative & support | 2020 |
| Plot 96 Ltd | Real estate | 2025 |
| Ploytime Limited | Households | 1988 |
| Plum Psychology Limited | Health & social care | 2023 |
| Plumbing on TAP Ltd | Extraterritorial | 2013 |
| Plunder Fish Games Ltd | Manufacturing | 2023 |
| PMB Project Services Ltd | Professional & scientific | 2013 |
| PMG Dent Limited | Health & social care | 2022 |
| PNB Project Management Services Limited | Information & communication | 2009 |
| Poda Sussex Ltd | Other services | 2025 |
| Podiatrust Clinic Limited | Health & social care | 2014 |
| Podium Ltd | Administrative & support | 2014 |
| Poet Marine Ltd | Professional & scientific | 2025 |
| Poets Corner Enterprises Ltd | Real estate | 2011 |
| Poets Electrical Limited | Construction | 2025 |
| POH Management Company Limited | Households | 2019 |
| Pointb People Limited | Professional & scientific | 2026 |
| Pointless Tech Limited | Professional & scientific | 2024 |
| Pokehaul Ltd | Wholesale & retail | 2025 |
| Pokestopbee Trading Cards Ltd | Wholesale & retail | 2024 |
| Polands Development Limited | Construction | 2024 |
| Polarity Reversal Limited | Information & communication | 2014 |
| Polenta Property Holdings Ltd | Construction | 2021 |
| Policis Limited | Professional & scientific | 2003 |
| Polka DOT Post Ltd | Information & communication | 2016 |
| Pollards Promises | Other services | 2019 |
| Pollards Properties Ltd | Real estate | 2021 |
| Polly Cockell Ltd | Professional & scientific | 2018 |
| Polymath Engineering Solutions Ltd | Professional & scientific | 2025 |
| Pondhop Ltd | Professional & scientific | 2025 |
| Pondtree Limited | Real estate | 1983 |
| Pontisgroup Ltd | Wholesale & retail | 2025 |
| Pook Fisheries Limited | Arts & recreation | 2017 |
| Pooltec Ltd | Construction | 2020 |
| Poor Monkey Limited | Information & communication | 2012 |
| POP Art Developments Limited | Construction | 2003 |
| POP OR WOT Limited | Wholesale & retail | 2025 |
| Pophaus Ltd | Administrative & support | 2026 |
| Popogami Limited | Professional & scientific | 2013 |
| Poppy Co (UK) Limited | Administrative & support | 2014 |
| Popupspace Ltd | Information & communication | 2008 |
| Port Capital Ltd | Other services | 2020 |
| Port Group Limited | Construction | 2018 |
| Port Hall Consultancy Limited | Administrative & support | 2005 |
| Port Kitchen Ltd | Hospitality | 2025 |
| Port Newton Limited | Financial services | 2019 |
| Portello Limited | Real estate | 2023 |
| Porteous Holdings Limited | Financial services | 2019 |