| Stirling Castle Construction Limited | Construction | 2023 |
| Stixley Limited | Other services | 2021 |
| Stjyt Limited | Wholesale & retail | 2026 |
| Stockley Park Four FG Limited | Real estate | 2025 |
| Stockley Park Four Limited | Real estate | 2024 |
| Stockley Park Four LW Limited | Real estate | 2025 |
| Stockley Park Hospital Limited | Health & social care | 2026 |
| Stockley Park SIX Limited | Real estate | 2023 |
| Stockley Park Three Limited | Real estate | 2024 |
| Stockley Park Three RW Limited | Real estate | 2025 |
| Stockley Park Three SQ Limited | Real estate | 2025 |
| Stockley Park Two FG Limited | Real estate | 2025 |
| Stockley Park Two Limited | Real estate | 2025 |
| Stoicamarian Ltd | Administrative & support | 2025 |
| Stoke Holdings Ltd | Construction | 2024 |
| Stomach UK Limited | Hospitality | 2026 |
| Stone Cliff International Ltd | Manufacturing | 2015 |
| Stone Oak Management Ltd | Real estate | 2022 |
| Stone Solution London Ltd | Manufacturing | 2018 |
| Stonebase Builders Ltd | Construction | 2025 |
| Stonebridge Cover Limited | Financial services | 2026 |
| Stonebridge Properties BR Ltd | Real estate | 2023 |
| Stonehut Limited | Real estate | 2020 |
| Stonekraft Construction Limited | Construction | 2023 |
| Stonelane Consultancy Limited | Health & social care | 2009 |
| Stonelane Universal Limited | Real estate | 2026 |
| Stones ISH Holdings Limited | Real estate | 2020 |
| Stop & Taste Limited | Hospitality | 2024 |
| Stop and Shop Convenience Store Limited | Wholesale & retail | 2021 |
| Stop Frailty Ltd | Information & communication | 2026 |
| Storefront Experts Ltd | Wholesale & retail | 2026 |
| Stour Avenue Ltd | Real estate | 2025 |
| Stoyanov Builders Limited | Construction | 2019 |
| Stract Consulting Limited | Other services | 2019 |
| Strands Salons Ltd | Other services | 2014 |
| Strands Universe Ltd | Wholesale & retail | 2014 |
| Strap Accessories Ltd | Manufacturing | 2021 |
| Strategic Graphics Ltd | Professional & scientific | 2026 |
| Strategic Logistic Ltd | Construction | 2023 |
| Strategic Tactical Regional Alliance & Partnership Ltd | Professional & scientific | 2023 |
| Strategicore Ltd. | Administrative & support | 2016 |
| Stratofy IO Ltd | Information & communication | 2025 |
| Strawberry Central Limited | Wholesale & retail | 2024 |
| Strawberry Express Ltd | Wholesale & retail | 2013 |
| Strawberry Lease Ltd | Households | 2024 |
| Strawberry Local ( East ) Ltd | Wholesale & retail | 2017 |
| Strawberry Local Group Ltd | Wholesale & retail | 2017 |
| Strawberry Mama Limited | Wholesale & retail | 2020 |
| Strawberry Smart Limited | Wholesale & retail | 2025 |
| Street 21 Limited | Hospitality | 2023 |
| Street Bite Food Limited | Hospitality | 2025 |
| Street King Chicken Ltd | Hospitality | 2022 |
| Street Media Ltd | Administrative & support | 2016 |
| Strollers Limited | Real estate | 2020 |
| Strongwell Construction Ltd | Construction | 2025 |
| Strongwell Decorating Ltd | Construction | 2026 |
| Structural Carpentry and Roofing Ltd | Manufacturing | 2023 |
| Stryk Sports Ltd | Wholesale & retail | 2025 |
| STS AV Ltd | Manufacturing | 2019 |
| Studentwise Technology Limited | Information & communication | 2021 |
| Studio 75 CIC | Information & communication | 2025 |
| Studio Graphite Ltd | Wholesale & retail | 2024 |
| Study Switch Ltd | Wholesale & retail | 2018 |
| Style and Glamour London Ltd | Wholesale & retail | 2017 |
| Stylie Ltd | Other services | 2025 |
| Stylish Barber AB Ltd | Other services | 2019 |
| Stylish Surfaces Ltd | Professional & scientific | 2026 |
| Suavis Capital Ltd | Financial services | 2021 |
| Subha Aarambha Limited | Wholesale & retail | 2024 |
| Sublime Logistics Ltd | Transport & logistics | 2020 |
| Sublime Sourcing Ltd | Transport & logistics | 2021 |
| Sublime Swim Skool Ltd | Arts & recreation | 2025 |
| Sublime Transport Ltd | Other services | 2022 |
| Sublime Vehicles Ltd | Wholesale & retail | 2024 |
| Subspicy Ltd | Manufacturing | 2025 |
| Success for Future Education Ltd | Education | 2026 |
| Succour Solutions Ltd | Administrative & support | 2022 |
| Sufal Ltd | Real estate | 2024 |
| Suffah School Ltd | Education | 2026 |
| Suffah Services Limited | Information & communication | 2011 |
| Sugam Ltd | Professional & scientific | 2019 |
| Sugar Rush Bakes Ltd | Hospitality | 2025 |
| Suhaibakhlaq Ltd | Wholesale & retail | 2020 |
| Suite Spot Property Limited | Real estate | 2023 |
| Sukchen Ltd | Wholesale & retail | 2019 |
| Sukh Construction & Roofing Ltd | Transport & logistics | 2025 |
| Sukh Energy Ltd | Wholesale & retail | 2018 |
| Sukh Toor Ltd | Construction | 2026 |
| Sukhal Care Limited | Health & social care | 2022 |
| Sukhchen Ltd | Wholesale & retail | 2022 |
| Sukhmani Sahib Parivaar | Education | 2019 |
| Sukhsimran Properties Ltd | Real estate | 2024 |
| Sukman Estate Ltd | Real estate | 2016 |
| Sukoon Ltd | Administrative & support | 2004 |
| Suleman's Real Estate Limited | Real estate | 2021 |
| Sulley Healthcare Services Limited | Health & social care | 2013 |
| Sulltan Ltd | Administrative & support | 2026 |
| Sultan & Brothers Limited | Administrative & support | 2025 |
| Sultan Bike Repairs & Auto Parts Ltd | Wholesale & retail | 2026 |
| Sultan Properties Limited | Real estate | 2016 |