| SP Bains Builder Limited | Construction | 2020 |
| SP Financial Risk Consultancy Limited | Financial services | 2009 |
| SP RA Limited | Wholesale & retail | 2019 |
| SP Staines Road Hounslow Ltd | Real estate | 2020 |
| Space Construction Solutions Ltd | Construction | 2025 |
| Spacelane Interiors & Consulting Limited | Professional & scientific | 2026 |
| Spaceranger Limited | Hospitality | 2007 |
| Spark - IT Electricals Limited | Construction | 2014 |
| Spark Digital Technologies Ltd | Professional & scientific | 2024 |
| Spark Fuel Ltd | Wholesale & retail | 2019 |
| Spark Strategists Ltd | Information & communication | 2025 |
| Sparkles Cleaning Services Ltd | Wholesale & retail | 2025 |
| Sparkling Bubbles Cleaning Solutions Limited | Administrative & support | 2024 |
| Sparkpk Ltd | Construction | 2018 |
| Spartan Force Ltd | Construction | 2025 |
| Spartan Roofing Improvements Ltd | Construction | 2026 |
| Spathe (PVT) Ltd | Health & social care | 2012 |
| Specialistcrewent Ltd | Hospitality | 2025 |
| Specialized Storage Solutions Limited | Manufacturing | 2025 |
| Spectrum Delivery Limited | Professional & scientific | 2025 |
| Spectrum Digital Print Ltd | Manufacturing | 2013 |
| SPEEDBIRD1 Limited | Administrative & support | 2010 |
| Speeds Transport Service Ltd | Transport & logistics | 2025 |
| Speedway Executive Travel Ltd | Transport & logistics | 2026 |
| Speedwings Cars Ltd | Administrative & support | 2023 |
| Speedwings Group Limited | Transport & logistics | 2023 |
| Speedwings Haulage Ltd | Transport & logistics | 2023 |
| Speedy Links Ltd | Transport & logistics | 2021 |
| Speedy Slice Limited | Hospitality | 2025 |
| Speedyfix Auto Solutions Limited | Wholesale & retail | 2020 |
| Spencer Avenue Investments Ltd | Real estate | 2024 |
| Speze Limited | Wholesale & retail | 2018 |
| Spherescope Media Limited | Information & communication | 2014 |
| Sphinx Electronics Ltd | Manufacturing | 2013 |
| Spice Darbar Ltd | Hospitality | 2023 |
| Spice Delight Sweets and Snacks Ltd | Wholesale & retail | 2021 |
| Spice of Lahore Ltd | Hospitality | 2025 |
| Spicysub Ltd | Manufacturing | 2023 |
| Spiro Buildings Ltd | Construction | 2023 |
| SPL (PTE) Ltd | Hospitality | 2014 |
| Splash Styles Limited | Construction | 2018 |
| Splr Gentle Care Ltd | Health & social care | 2025 |
| Spoorthi Consultancy Limited | Information & communication | 2018 |
| Sporticus of London Ltd | Wholesale & retail | 2021 |
| Sposla Ltd | Real estate | 2019 |
| Spot the Deal Ltd | Information & communication | 2019 |
| Spotell Ltd | Wholesale & retail | 2014 |
| Spotlight PR Limited | Professional & scientific | 2024 |
| Spovens Limited | Information & communication | 2012 |
| SPR Catering Ltd | Hospitality | 2026 |
| SPR Tech Ltd | Manufacturing | 2026 |
| SPRAYMASTER1 Limited | Construction | 2025 |
| Spring Grove Homes Limited | Real estate | 2025 |
| Spring of Life Ministry | Other services | 2016 |
| Springwell Logistcs Ltd | Transport & logistics | 2026 |
| SPS Goods Ltd | Wholesale & retail | 2025 |
| Square Mile Services Group Limited | Administrative & support | 2022 |
| Square Walls Limited | Real estate | 2009 |
| Squirrel Realty 6 Limited | Real estate | 2025 |
| Squirrels Day Nursery (London) Ltd | Education | 2024 |
| SR & K Holdings Limited | Real estate | 2025 |
| SR and a Stores Ltd | Wholesale & retail | 2021 |
| SR Curry Ltd | Hospitality | 2025 |
| SR Trading NW Ltd | Other services | 2025 |
| SR3C Properties Ltd | Real estate | 2024 |
| SRA Properties Limited | Real estate | 2013 |
| SRA Technologies Limited | Information & communication | 2013 |
| Sraa Tech Limited | Information & communication | 2023 |
| SRE Portfolio Management Ltd | Financial services | 2022 |
| Sree Mahalakshmi Ltd | Wholesale & retail | 2025 |
| SRG Family Property Investment Ltd | Real estate | 2023 |
| SRH Hair & Beauty Spa Ltd | Other services | 2023 |
| SRI Advaitha Seva and Cultural UK Ltd | Other services | 2025 |
| SRI Avyay Limited | Hospitality | 2025 |
| SRI Durga Foods Limited | Hospitality | 2025 |
| SRI Gurunanak Limited | Wholesale & retail | 2025 |
| SRI Lakshmi Srinivasa Delight Ltd. | Hospitality | 2024 |
| SRI Lakshmi Venkateshwara Innovations Ltd | Information & communication | 2022 |
| SRI Padmakar Seva and Cultural UK Ltd | Professional & scientific | 2026 |
| SRI Radha Krishna Properties UK Limited | Real estate | 2023 |
| SRI Rajarajeswari Devi Services Ltd | Hospitality | 2024 |
| SRI Sadhvi Ltd | Construction | 2020 |
| Sridivya IT Solutions Limited | Information & communication | 2016 |
| Sriverse Reality Ltd | Construction | 2025 |
| Sriviri Enterprise Ltd | Hospitality | 2025 |
| SRJ Accountancy Ltd | Professional & scientific | 2022 |
| SRK Constructions London Ltd | Construction | 2019 |
| SRK Finance Ltd | Financial services | 2025 |
| SRK Law Limited | Professional & scientific | 2025 |
| Srkmotors Ltd | Wholesale & retail | 2026 |
| SRL Communications Limited | Professional & scientific | 2022 |
| SRL Research Laboratory Limited | Information & communication | 2022 |
| Srlglobal Software Solutions Ltd | Information & communication | 2011 |
| SRM 98 Ltd Ltd | Construction | 2026 |
| SRN Brothers Ltd | Construction | 2025 |
| SRP UK Investments Ltd | Real estate | 2016 |
| SS Bespoke Kitchens and Bedrooms Limited | Wholesale & retail | 2024 |
| SS Builders and Repairs Limited | Construction | 2011 |
| SS Consultancy Ltd | Professional & scientific | 2023 |
| SS Enterprise London Limited | Construction | 2024 |