| Easton Design Studio Limited | Wholesale & retail | 2006 |
| Easyline Communications Limited | Administrative & support | 2001 |
| Eaton Place Residents Management Company Limited | Households | 2013 |
| Eazychem Limited | Wholesale & retail | 2002 |
| EB Comms Ltd | Professional & scientific | 2025 |
| Ebony Penny Real Estate Ltd | Real estate | 2019 |
| Ebusco Intl Ltd | Wholesale & retail | 2026 |
| EC Property Group Ltd | Real estate | 2024 |
| Echelon Public Relations Ltd | Professional & scientific | 2021 |
| Echobronze Ltd | Arts & recreation | 2017 |
| Ecko Interiors Ltd | Construction | 2024 |
| Eclipse Broadband Limited | Information & communication | 2020 |
| Eclipse Golf Ltd | Education | 2015 |
| Ecmp Ltd | Professional & scientific | 2017 |
| Eco Power Shop Ltd | Wholesale & retail | 2012 |
| Eco-Asphalt Limited | Construction | 1992 |
| Econotech Limited | Manufacturing | 1986 |
| Edburton Motte Investments Group Limited | Information & communication | 2022 |
| EDG Automotive Ltd | Wholesale & retail | 2025 |
| Edgcote Limited | Administrative & support | 2008 |
| Edge Assessors Ltd | Real estate | 2017 |
| Edgeler Book Services Limited | Other services | 1998 |
| EDL Coaching Limited | Arts & recreation | 2020 |
| Edmund TSO Limited | Health & social care | 2017 |
| Edstone Legal Limited | Professional & scientific | 2025 |
| EDU Finance Ltd | Professional & scientific | 2024 |
| EFT Finance (Holdings) Ltd | Financial services | 2023 |
| EFT Finance Limited | Administrative & support | 2010 |
| EG Land Ltd | Construction | 2026 |
| Eghepeters Healthcare Ltd | Health & social care | 2014 |
| Egmont Park House Residents Management Limited | Households | 1986 |
| Eidgha Limited | Real estate | 2011 |
| EJC Team Ltd | Administrative & support | 2026 |
| EJW Consulting Services Limited | Information & communication | 2025 |
| EKO Mattress Ltd | Manufacturing | 2024 |
| Ekralc Ltd | Professional & scientific | 2020 |
| EL Hastings Ltd | Health & social care | 2015 |
| Eladoria Ltd | Wholesale & retail | 2025 |
| Elanvia Consulting Ltd | Information & communication | 2025 |
| Elara Medical Services Ltd | Health & social care | 2022 |
| ELB IAN Bradley Construction Services Ltd | Construction | 2025 |
| Electric Avenue Charging Ltd | Construction | 2022 |
| Electrotek Services Limited | Construction | 2017 |
| Elem Communications Limited | Professional & scientific | 2015 |
| Elementree Group Limited | Administrative & support | 2015 |
| Elementus Limited | Professional & scientific | 2011 |
| Elevare Investments Ltd | Real estate | 2019 |
| Elevate Advisory Ltd | Information & communication | 2024 |
| Elevate Fitness London Ltd | Health & social care | 2023 |
| Elevate Scientific Solutions Limited | Professional & scientific | 2018 |
| Elevation Imaging Limited | Administrative & support | 2018 |
| Elia Kalamata Ltd | Wholesale & retail | 2024 |
| Eliot Place Consulting Ltd. | Professional & scientific | 2016 |
| Elira Group Ltd | Information & communication | 2026 |
| Elise Rawson the Neuro Physio Ltd | Health & social care | 2022 |
| Elite Group of Companies Limited | Wholesale & retail | 2018 |
| Elite Living Healthcare Ltd | Health & social care | 2025 |
| Elite Vehicle Servicing Limited | Wholesale & retail | 2020 |
| Elixens UK Ltd | Manufacturing | 1959 |
| Ella Mcewan Ltd | Administrative & support | 2018 |
| Ellie's TTH Services Ltd | Administrative & support | 2022 |
| Elliot Boothman Ltd | Professional & scientific | 2018 |
| Elliott Financial Services Ltd | Financial services | 2003 |
| Ellis Holdings and Estates Limited | Real estate | 2024 |
| Ellisleigh Estates Limited | Real estate | 2007 |
| Elmhurst Farm Ltd | Administrative & support | 2026 |
| Elmo Software Limited | Information & communication | 2021 |
| Elmo Software UK Holdings Limited | Information & communication | 2020 |
| Elohim Compliance Services Ltd | Professional & scientific | 2017 |
| Eloquent Limited | Information & communication | 2009 |
| Eloquent Scientific Solutions Limited | Professional & scientific | 2018 |
| Eloquin Consultancy Ltd | Health & social care | 2012 |
| Elteco Global Holding Ltd | Financial services | 2019 |
| Eltons Estate Agents Ltd | Real estate | 2023 |
| Elysian BTL Ltd | Real estate | 2018 |
| EM Home Real Estate Limited | Real estate | 2025 |
| Ember Rock Limited | Construction | 2025 |
| Emberstone Ltd | Real estate | 2025 |
| Emens Osteopathic Clinics Limited | Health & social care | 2026 |
| Emjay Consultancy Limited | Information & communication | 2009 |
| EMK Developments Ltd | Construction | 2010 |
| Emma Coomber Careers Consultant Ltd | Education | 2024 |
| Emma Samman Ltd | Professional & scientific | 2015 |
| Emmanuel Gail Asher Ltd | Professional & scientific | 2022 |
| Emmas Rectangle Ltd | Information & communication | 2021 |
| Emmett Interiors and Gardens Ltd | Professional & scientific | 2026 |
| Empathic Psychology Limited | Health & social care | 2023 |
| Empirical Consulting Limited | Information & communication | 2007 |
| Employee Volunteering C.I.C. | Administrative & support | 2006 |
| Employee Volunteering Group Limited | Information & communication | 2020 |
| Empowered Nutrition Ltd | Wholesale & retail | 2025 |
| Emptytaxis Limited | Transport & logistics | 2021 |
| Emra Health Ltd | Health & social care | 2023 |
| Enable Consultants Limited | Professional & scientific | 2011 |
| Enabling YOU Ltd | Health & social care | 2013 |
| ENB Commercial Ltd | Construction | 2014 |
| ENB Electrical Ltd | Construction | 2014 |
| Encara Ltd | Administrative & support | 2011 |
| Enchange Limited | Professional & scientific | 1993 |
| Endacott Property Limited | Real estate | 2018 |