| Sejc Consulting Engineers Limited | Construction | 2003 |
| Sejc Holdings Limited | Professional & scientific | 2009 |
| Seven EOT Limited | Financial services | 2022 |
| Sharma Medical Services Provision Limited | Health & social care | 2024 |
| Sharp Trading Co Ltd | Administrative & support | 2003 |
| Shlht Plans Ltd | Administrative & support | 2021 |
| Shotton Jumps Limited | Arts & recreation | 2024 |
| Simon Green Motor Engineers Limited | Wholesale & retail | 2009 |
| Simulation Software Limited | Information & communication | 1977 |
| Site Line Developments LLP | | 2015 |
| Skydive Academy Ltd | Arts & recreation | 1996 |
| Skyhigh Ground Services Limited | Hospitality | 2020 |
| Skyhigh Plane Services Limited | Manufacturing | 2020 |
| Social Frenzy Ltd | Professional & scientific | 2021 |
| Sonico Productions Limited | Information & communication | 2013 |
| Sorbo Ltd | Wholesale & retail | 2024 |
| Sovereign Stream Limited | Professional & scientific | 2016 |
| Spark Building Projects Limited | Households | 2025 |
| Spark Electrical Projects Limited | Construction | 2022 |
| Sports 3.0 UK Limited | Professional & scientific | 2018 |
| Squire for MEN Ltd | Other services | 2023 |
| Streamtech Ltd | Information & communication | 2019 |
| Strongly Property Limited | Real estate | 2024 |
| Studio Build Ltd | Professional & scientific | 2007 |
| Studio Orbit Limited | Education | 2022 |
| Subterra Solutions Ltd | Construction | 2024 |
| Sunderland Parachute Centre Limited | Arts & recreation | 1978 |
| Surecert Limited | Real estate | 2003 |
| Sweeny Developments Limited | Real estate | 2023 |
| Sweeny LLP | | 2018 |
| Syrinx Resource Old | | 1991 |
| Tees Aliance Gilbran (Management) Limited | Professional & scientific | 2021 |
| Tees Alliance Gilbran Limited | Real estate | 2021 |
| Templer Management Limited | Wholesale & retail | 2010 |
| THE Entitled Sons LLP | | 2022 |
| THE Folding Mirror Limited | Information & communication | 2016 |
| THE Funding Globe Limited | Financial services | 2008 |
| THE Hollies 2003 Management Company Limited | Households | 2003 |
| THE Nook Peckham Ltd | Hospitality | 2022 |
| TIM Sugden Motorsport Limited | Arts & recreation | 1992 |
| Total Renovations (Yorkshire) Ltd | Construction | 2021 |
| TSH Services Limited | Administrative & support | 2016 |
| Turner & Townsend (USA) Limited | Administrative & support | 2000 |
| Turner & Townsend Limited | Administrative & support | 2008 |
| Twenty Plus SIX Ltd | Wholesale & retail | 2024 |
| Tyreman Group Limited | Financial services | 2015 |
| UK Knee Crutches Limited | Wholesale & retail | 2018 |
| Universal Property Interests Limited | Real estate | 1946 |
| Unusual Returns Limited | Professional & scientific | 2025 |
| Vane House Limited | Professional & scientific | 2007 |
| VAT Bridge (Bloomsmith) Limited | Extraterritorial | 2022 |
| Verity Green Spaces CIC | Administrative & support | 2021 |
| Verity Group Holdings Limited | Real estate | 2019 |
| Verity Industrial Developments Limited | Professional & scientific | 2020 |
| Verity Land and Development Services Limited | Professional & scientific | 2020 |
| Verity Open Spaces Limited | Administrative & support | 2020 |
| Verity Residential Developments Limited | Construction | 2020 |
| Vially (GB) Limited | Information & communication | 2023 |
| Vinny's Bottle Shop Ltd | Wholesale & retail | 2021 |
| Vivatec Safety Ltd | Construction | 2020 |
| Vogue Pressure Washing Ltd | Administrative & support | 2021 |
| Wardshaw Limited | Households | 1982 |
| Webster Management Partnership LLP | | 2012 |
| West Wing Doctors Limited | Health & social care | 2011 |
| Westbrooks Brewery Limited | Wholesale & retail | 2021 |
| Westcliffe Landings Ltd | Professional & scientific | 2022 |
| Westcliffe Partnerships Ltd | Administrative & support | 2021 |
| Westminster Roofing Limited | Construction | 2017 |
| When It's Gone Warehouse Sales Limited | Information & communication | 2002 |
| White Horse Carpets Limited | Wholesale & retail | 2003 |
| William & Robert, Ltd | Other services | 2021 |
| Window & Door Supplies Ltd | Construction | 2020 |
| Windsor Holdco Limited | Financial services | 2023 |
| WT Racing LLP | | 2014 |
| Yorkshire Property Design Services Ltd | Professional & scientific | 2020 |
| Yorkshire Quality Homecare Ltd | Health & social care | 2022 |
| Yorkshire Shoulder Physiotherapy LLP | | 2016 |
| ZAP Family Investments Limited | Financial services | 2023 |