| CDR Mapping Limited | Information & communication | 1991 |
| Cedric Properties Limited | Professional & scientific | 2000 |
| Centre for Shamanic Arts | Education | 2018 |
| Chantrey House Nursery Limited | Education | 2013 |
| Chatsworth Property and Estate Ltd | Real estate | 2021 |
| Chippingham Ltd | Administrative & support | 2018 |
| Chloe Palmer (Farm & Environment) Consultancy Limited | Professional & scientific | 2011 |
| Chris Jackson Consultants Limited | Professional & scientific | 2014 |
| Cintra's Cafe & Restaurant Ltd | Hospitality | 2003 |
| Clark Financial Advisory Limited | Financial services | 2013 |
| Clearholdinovations Limited | Manufacturing | 2026 |
| Clearland Consulting Ltd | Construction | 2024 |
| CNH Property Limited | Construction | 2021 |
| Coach House Stores Castleton Ltd | Wholesale & retail | 2021 |
| Colina Bikes Limited | Wholesale & retail | 2015 |
| Comitas Financial Solutions Limited | Financial services | 2022 |
| Contour Brewing Ltd | Manufacturing | 2024 |
| Contract Data Research Limited | Information & communication | 1985 |
| Cork Dermatology Consulting Ltd | Health & social care | 2019 |
| Crag Access Limited | Wholesale & retail | 2019 |
| Cranmore Grange Limited | Wholesale & retail | 1983 |
| Crash Pads UK Limited | Real estate | 2009 |
| Cressbrook Construction Limited | Construction | 2025 |
| Crooks Architecture Ltd. | Professional & scientific | 2015 |
| Crosslow Farm Campsite and Accomodation Limited | Hospitality | 2024 |
| Curbar Industries Ltd | Real estate | 2021 |
| Curbar Properties Ltd | Real estate | 2019 |
| Curry Cottage Group Ltd | Hospitality | 2017 |
| Cutting Edge Tree Care Limited | Extraterritorial | 2009 |
| D Breen Consulting Ltd | Health & social care | 2022 |
| D P Fell Decorating Contractors Limited | Construction | 2006 |
| D R Rowland & N J Woodward Limited | Agriculture & fishing | 2014 |
| D S Sutherland Properties Ltd | Real estate | 2025 |
| D-Marc Limited | Manufacturing | 2008 |
| Dale Brook View Limited | Real estate | 2026 |
| Dantex Ltd | Professional & scientific | 2003 |
| Dark Peak Camper Vans Ltd | Wholesale & retail | 2020 |
| Dark Peak Soul Ltd | Hospitality | 2023 |
| Dark Peak Trading Limited | Professional & scientific | 2006 |
| Darwent Architecture Ltd | Professional & scientific | 2012 |
| Defined by Digital Ltd | Professional & scientific | 2013 |
| Delightful Living Limited | Manufacturing | 2010 |
| Derbyshire Caretaking and Property Services Ltd | Administrative & support | 2018 |
| Derbyshire Dales Engineering Limited | Extraterritorial | 2005 |
| Derbyshire Lettings Limited | Real estate | 2018 |
| Derwent Accommodation Limited | Hospitality | 2013 |
| Derwent Holdings Limited | Real estate | 2020 |
| Developing With Nicola Wood Ltd | Professional & scientific | 2017 |
| Devsectr Ltd | Information & communication | 2025 |
| Digby&Thompson Ltd | Hospitality | 2024 |
| Direct Charcoal Limited | Wholesale & retail | 2003 |
| Dragonshead Productions Limited | Information & communication | 2005 |
| Dreams in Paint Ltd | Wholesale & retail | 2020 |
| Drowned Villages Smokeries Ltd | Manufacturing | 2022 |
| Dynamik Consultants Limited | Financial services | 2025 |
| E S Hancock Ltd | Administrative & support | 2024 |
| E.T.White & Sons,Limited | Wholesale & retail | 1955 |
| Eashrish Limited | Health & social care | 2017 |
| Eat,Drink Sleep MP Ltd | Hospitality | 2019 |
| Edale Mill Limited | Real estate | 2010 |
| Eddistone Consulting Ltd | Professional & scientific | 2006 |
| Edelrid UK Limited | Wholesale & retail | 2025 |
| Edhaz Ltd | Real estate | 2023 |
| Educational Planning Books Limited | Information & communication | 1998 |
| Eliza Clark Limited | Manufacturing | 2024 |
| Endecotts Limited | Wholesale & retail | 1965 |
| Enovion Limited | Professional & scientific | 2016 |
| ET White & Sons Holdings Limited | Real estate | 2013 |
| Etervia Ltd | Information & communication | 2025 |
| Exalt IP Limited | Administrative & support | 2014 |
| Exell Services Ltd | Construction | 2021 |
| Eyam Museum Limited | Arts & recreation | 1989 |
| Eyam Museum Trading Limited | Wholesale & retail | 1994 |
| Eyambrook Properties Limited | Real estate | 2018 |
| Falconers Cottage Ltd | Hospitality | 2025 |
| Fanny and Clara Ltd | Other services | 2011 |
| Feelingood Limited | Arts & recreation | 2012 |
| Ferraris Limited | Other services | 1980 |
| Fine Grinding Limited | Other services | 1942 |
| Fitism Ltd | Arts & recreation | 2006 |
| Fivesquared Ltd | Professional & scientific | 2016 |
| Foolow Building Services Limited | Construction | 2003 |
| Foolow Ltd | Professional & scientific | 2021 |
| Foundry Food Group Ltd | Wholesale & retail | 2019 |
| Foundry Group Holdings Ltd | Financial services | 2025 |
| Foundry Holdings Ltd | Wholesale & retail | 2022 |
| Frontfoot Network Ltd | Administrative & support | 2011 |
| Fruition Designs Limited | Manufacturing | 1998 |
| Full Service History Limited | Wholesale & retail | 2000 |
| Fumex Limited | Professional & scientific | 2004 |
| G G Distribution Limited | Wholesale & retail | 2016 |
| Galactic Soul Exchange Services Limited | Information & communication | 2020 |
| Gary Shepherd Bespoke Tailors Limited | Manufacturing | 2011 |
| Gbew Trading Limited | Other services | 2007 |
| GE Garne Ltd | Professional & scientific | 2006 |
| Ginger Air Ltd | Arts & recreation | 2019 |
| Girls' Brigade International Council(The) | Health & social care | 1979 |
| Gladstone Housing Limited | Real estate | 2019 |
| Glenbrook Holdings Limited | Financial services | 2025 |
| Goldcrest Medico-Legal Ltd | Health & social care | 2023 |