| Elite Construction (SW) Limited | Construction | 2007 |
| Elles Property Ltd | Real estate | 2025 |
| Ember Watch Company Ltd | Manufacturing | 2025 |
| Enabling Visions Ltd | Extraterritorial | 2001 |
| Endsleigh Sporting Ltd | Arts & recreation | 2026 |
| Engage Electrical Ltd | Construction | 2023 |
| Enzien Performance Limited | Wholesale & retail | 2021 |
| Epec Electrical Services Limited | Construction | 2005 |
| Epec Services Limited | Construction | 2022 |
| Equillation Ltd | Education | 2025 |
| Ernsborough Gardens Management Limited | Households | 1980 |
| Errington Park Estates Limited | Construction | 2025 |
| Ethel and Cecil Limited | Wholesale & retail | 2019 |
| EV Hair Limited | Other services | 2023 |
| Ever Greens Services Limited | Other services | 2016 |
| Every Nominees Limited | Financial services | 1996 |
| Everys Asset Management Limited | Financial services | 2013 |
| Everys Capital Limited | Financial services | 2014 |
| Everys Solicitors LLP | | 2016 |
| Evo's Media Limited | Information & communication | 2023 |
| Exact Scanning Solutions Ltd | Information & communication | 2025 |
| Excel Audio Systems Limited | Manufacturing | 1996 |
| Excel Elegance Hair Limited | Wholesale & retail | 2026 |
| Executive Edge Limited | Professional & scientific | 2003 |
| Exeter Dogwalkers Ltd | Other services | 2019 |
| Exeter Logistics Limited | Transport & logistics | 2017 |
| Exeter Petsitters Ltd | Other services | 2019 |
| Exeter Project Management Services Limited | Professional & scientific | 2013 |
| Exeter Stoves & Chimneys Ltd | Construction | 2012 |
| Exeter Travel Limited | Extraterritorial | 2008 |
| Exmouth Consulting Limited | Information & communication | 2004 |
| Exmouth Property Ltd | Real estate | 2025 |
| Exmouth Self Storage Ltd | Administrative & support | 2006 |
| Express Recycling Limited | Water & waste | 2006 |
| Extensio Digital Limited | Professional & scientific | 2019 |
| Eyegloo Limited | Real estate | 2024 |
| Eyemater Limited | Professional & scientific | 2014 |
| F C & L Pyle Limited | Agriculture & fishing | 2018 |
| F.J. Developments Limited | Real estate | 2006 |
| Face OFF Promotions Ltd | Arts & recreation | 2023 |
| Fairlead Ltd | Transport & logistics | 2026 |
| Fanytrans Ltd | Transport & logistics | 2025 |
| Faraday Heating Limited | Wholesale & retail | 2004 |
| Farmer and Roper Limited | Extraterritorial | 1973 |
| FB Building Consultancy Ltd | Professional & scientific | 2021 |
| FD Dent Ltd | Health & social care | 2022 |
| Fenchurch Decorating Ltd | Other services | 2018 |
| Fenchurch Property Management Ltd | Real estate | 2019 |
| Feniton Hairstylists Limited | Other services | 2016 |
| Find My Legal Team Ltd | Professional & scientific | 2010 |
| Finishings SW Ltd | Construction | 2026 |
| Finlay Popham Developments Ltd | Construction | 2025 |
| Fire Damper Remedial Company Limited | Manufacturing | 2024 |
| Firecore Management Ltd | Construction | 2025 |
| First Light Home Improvements Limited | Construction | 2020 |
| Fitness Clinic Exeter Ltd | Arts & recreation | 2019 |
| Fleet Building Solutions Ltd | Construction | 2016 |
| Flexatron Ltd | Health & social care | 2019 |
| Florence Graham Ltd | Professional & scientific | 2025 |
| Flyhigh.Buzz Limited | Transport & logistics | 2014 |
| FMZ Traders Limited | Wholesale & retail | 2025 |
| Focus on Britain Ltd | Information & communication | 2017 |
| Focus on Plants Limited | Extraterritorial | 2010 |
| Foliar Concept Limited | Extraterritorial | 1994 |
| Follow Focus Films Limited | Information & communication | 2025 |
| Foodsave CIC | Hospitality | 2023 |
| Foresters Management (Taunton) Ltd | Households | 2022 |
| Fortitude Software Ltd | Information & communication | 2025 |
| Foundry Automotive LLP | | 2022 |
| Four Elms Holiday Rentals Ltd | Real estate | 2024 |
| Four Star Products Limited | Extraterritorial | 2002 |
| FOX Growers Ltd | Agriculture & fishing | 2021 |
| Foxwell Property Holdings Ltd | Real estate | 2025 |
| Franchise Consultants Limited | Wholesale & retail | 2013 |
| Franco Dent Ltd | Health & social care | 2022 |
| Frying Trapeze Catering Ltd | Wholesale & retail | 2026 |
| Futurenova Holdings Ltd | Financial services | 2025 |
| Futurenova Living Ltd | Health & social care | 2025 |
| G Sky Care Limited | Health & social care | 2023 |
| G Trott Tree Consultancy Limited | Professional & scientific | 2025 |
| G-Bkvg Limited | Arts & recreation | 1985 |
| G. G. Locke Limited | Other services | 2000 |
| G3 Promotions Limited | Wholesale & retail | 2024 |
| G3 Promotions South West Limited | Wholesale & retail | 2013 |
| GAB & MAR Limited | Construction | 2026 |
| Gair Green Limited | Professional & scientific | 2022 |
| Galeano Dent Ltd | Health & social care | 2018 |
| Gamut Systems Limited | Information & communication | 1993 |
| Ganesha Wholefoods Holdings Limited | Financial services | 2025 |
| Ganesha Wholefoods Limited | Wholesale & retail | 2002 |
| Gertie and Bertie Limited | Wholesale & retail | 2019 |
| Giggabyte Limited | Other services | 1996 |
| Gillingham Bell Limited | Administrative & support | 2004 |
| Girling Family Co Ltd | Real estate | 2018 |
| Glanville Investments Ltd | Real estate | 2020 |
| GNT Partners Ltd | Financial services | 2024 |
| Gold Acre Woodlands Ltd | Agriculture & fishing | 2019 |
| Good Therapy Ltd | Health & social care | 2022 |
| Goren Festival Limited | Hospitality | 2017 |
| GPG Contracting Limited | Professional & scientific | 2016 |