| Ecomech-Uk Limited | Construction | 2023 |
| Ecore Electrical Ltd | Construction | 2012 |
| Ecosolar UK Ltd | Professional & scientific | 2021 |
| Eddie Ashby Limited | Administrative & support | 2015 |
| Edwards Property (Hinckley) Company Limited | Real estate | 1961 |
| EJ Truck Wash Ltd | Administrative & support | 2024 |
| Ejem Ltd | Wholesale & retail | 2016 |
| EKO-78 Ltd | Real estate | 2024 |
| EL Car Sales Ltd | Wholesale & retail | 2025 |
| EL Tonelero Limited | Hospitality | 2021 |
| Elangeni Ltd | Hospitality | 2022 |
| Elbow Room Alehouse Ltd | Hospitality | 2015 |
| Electric Chapel Ltd | Hospitality | 2023 |
| Electric Riot Designs Ltd | Arts & recreation | 2026 |
| Electric Skies Ltd | Information & communication | 2017 |
| Electrical Solutions (Midlands) Limited | Construction | 2019 |
| Elite Biotics Ltd | Health & social care | 2025 |
| Elite Electrical Services and Contractors Limited | Construction | 2023 |
| Elizabeth R G Ltd | Information & communication | 2025 |
| Eljans Limited | Wholesale & retail | 2016 |
| Elloro Limited | Information & communication | 2022 |
| Elmesthorpe Brewery Co Limited | Wholesale & retail | 2016 |
| Elmleigh Electrical Systems Limited | Manufacturing | 2006 |
| Elms Plumbing and Heating Limited | Construction | 2003 |
| Elmstone Mechanical Services Limited | Construction | 2026 |
| EM Truck Paint Ltd | Wholesale & retail | 2021 |
| EMAAAEST1982 Limited | Wholesale & retail | 2024 |
| Embody Dance Limited | Education | 2025 |
| Embody Futures Limited | Arts & recreation | 2024 |
| EMC Company Holdings Ltd | Manufacturing | 2026 |
| EMC20 Ltd | Agriculture & fishing | 2020 |
| Emerald Core Ltd | Wholesale & retail | 2026 |
| Emilur Ltd | Professional & scientific | 2022 |
| Emma Crocker Ltd | Financial services | 2024 |
| Emma Trucking Limited | Transport & logistics | 2018 |
| Emmaus Leicestershire and Rutland | Hospitality | 2011 |
| Emmerson (Construction Services) Ltd | Professional & scientific | 2017 |
| Empire Drinks and Refrigeration (NEWCO1) Limited | Financial services | 2026 |
| Empire Drinks and Refrigeration Limited | Wholesale & retail | 2006 |
| Empire Fitness Limited | Arts & recreation | 1997 |
| Empire Serviced Apartments Limited | Real estate | 2017 |
| Empire UK Rentals Ltd | Real estate | 2019 |
| EMR Consultants Ltd | Professional & scientific | 2016 |
| Enersolgas Ltd | Construction | 2017 |
| Ennf Limited | Information & communication | 2018 |
| Ensco 1420 Limited | Financial services | 2021 |
| Ensco 1426 Limited | Real estate | 2021 |
| Ensconce Network Supplies Limited | Wholesale & retail | 2014 |
| Entegraty Limited | Information & communication | 2006 |
| Entegraty Professional Services Limited | Information & communication | 2006 |
| Enterprise Labels LLP | | 2012 |
| Enterprise Workwear Hinckley LLP | | 2017 |
| Enterprise Workwear Ltd | Wholesale & retail | 2012 |
| Enurcomm Solutions Limited | Construction | 2010 |
| Envirolex Management Ltd | Professional & scientific | 1998 |
| Epicurean Lounge Limited | Wholesale & retail | 2023 |
| Epowersports Ltd | Wholesale & retail | 2020 |
| Equess Limited | Wholesale & retail | 2017 |
| Eridian Stone Ltd | Professional & scientific | 2025 |
| Eruditus Limited | Real estate | 2016 |
| Escapade 10 Ltd | Real estate | 2021 |
| Escapade 33 Limited | Financial services | 2022 |
| Escapen Ltd | Arts & recreation | 2025 |
| Essential Facilities Management Ltd | Households | 2026 |
| Essentials Health & Beauty Clinic Limited | Other services | 2014 |
| Established Consultants Ltd | Other services | 2025 |
| Eternity Diamonds Limited | Manufacturing | 2002 |
| Ettlogic Ltd | Information & communication | 2025 |
| Etuk Transfers Limited | Transport & logistics | 2022 |
| Europa Trading Partners Ltd | Professional & scientific | 2023 |
| EV Accessories Limited | Wholesale & retail | 2018 |
| EVA Antoniou Interior Design Ltd | Professional & scientific | 2013 |
| Evans Bros Limited | Construction | 2001 |
| Evans Electrical Services (Midland) Ltd | Energy | 2015 |
| Evans Energy O&M Ltd | Manufacturing | 2025 |
| Evans Leicester Limited | Financial services | 2012 |
| Everest 8 Limited | Hospitality | 2022 |
| Everest Dine Limited | Hospitality | 2025 |
| Evergreens Florist Nuneaton Ltd | Other services | 2025 |
| Everyday Living Limited | Health & social care | 2018 |
| Everyday Living Properties Ltd | Real estate | 2025 |
| Everyone Active Administration Services Limited | Arts & recreation | 2012 |
| Everyone Health Limited | Education | 2001 |
| Everything Golf Limited | Extraterritorial | 2017 |
| Evolution Anywhere UK Ltd | Information & communication | 2020 |
| Evolve IT Systems Limited | Information & communication | 2017 |
| Excel Driver Training Limited | Wholesale & retail | 2021 |
| Excelsior Europe Ltd | Health & social care | 2007 |
| Eximious Furniture Limited | Manufacturing | 2002 |
| Express Mini Market Hinckley Limited | Wholesale & retail | 2025 |
| Express Mini Market LE10 Ltd | Wholesale & retail | 2024 |
| Extremely Vintage Limited | Wholesale & retail | 2019 |
| Eyebright Designs Limited | Information & communication | 1994 |
| Eyerish Limited | Health & social care | 2022 |
| Ezotrans Limited | Transport & logistics | 2025 |
| F & J Edge Ltd | Hospitality | 2016 |
| F and R Carpentry Ltd | Construction | 2023 |
| F M Solutions and Systems Limited | Administrative & support | 2022 |
| F&F Engineering Ltd | Manufacturing | 2024 |
| F.E. Downes (Homes) Limited | Construction | 1985 |