| DR Ashley M. Croft Associates Limited | Professional & scientific | 2020 |
| DR Ashley M. Croft MD Public Health Consultancy Limited | Health & social care | 2010 |
| DR Caroline Champagne Limited | Health & social care | 2019 |
| DR Claire Eden-Brown Ltd | Health & social care | 2023 |
| DR Frank M Armstrong Consulting Limited | Professional & scientific | 2012 |
| DR Prab Morgan Limited | Health & social care | 2026 |
| DR S Sheth Ltd | Health & social care | 2015 |
| DR Shutterman Ltd | Construction | 2021 |
| Dragon Associates Limited | Professional & scientific | 2011 |
| Dragon PR Limited | Information & communication | 2013 |
| Dragon Sensory Ltd | Wholesale & retail | 2019 |
| Dragonet Consulting Ltd | Professional & scientific | 2018 |
| Drain Station Ltd | Water & waste | 2025 |
| Drake Financial Advisory Ltd | Information & communication | 2016 |
| Drape Code GC Limited | Manufacturing | 2024 |
| Draper Emporium Ltd | Arts & recreation | 2022 |
| Drayton Freeholders Ltd | Real estate | 2018 |
| Dreadz Martial Arts Equipment Limited | Wholesale & retail | 2011 |
| Dream Build (Hazlemere) Limited | Construction | 2024 |
| Dream Dimension Ltd | Information & communication | 2011 |
| Dream House Constructions Ltd | Construction | 2010 |
| Dreamhomegroup Ltd | Real estate | 2021 |
| Dreamhometeam Ltd | Real estate | 2025 |
| Dreamline Properties Ltd | Real estate | 2024 |
| Dreams & Designs Places Ltd | Real estate | 2024 |
| Dreams Holdco Limited | Financial services | 2013 |
| Dreams Limited | Wholesale & retail | 2013 |
| Dreams Topco Limited | Financial services | 2013 |
| Dreamstaysa Limited | Real estate | 2025 |
| Drend Ltd | Wholesale & retail | 2022 |
| Dress UP Arena Ltd | Wholesale & retail | 2024 |
| Drew Analytics Consulting Limited | Administrative & support | 2015 |
| Drew Holdings Limited | Professional & scientific | 1986 |
| Drive and Buy Ltd | Wholesale & retail | 2021 |
| Drive Classics Ltd | Wholesale & retail | 2021 |
| Drive Co Cars Ltd | Wholesale & retail | 2025 |
| Driveace Ltd | Extraterritorial | 2025 |
| Driven Networks Limited | Professional & scientific | 2008 |
| Driveon World Ltd | Other services | 2025 |
| Driveroid Ltd | Information & communication | 2025 |
| Drivex Global Ltd | Wholesale & retail | 2025 |
| Drivvy Tests Ltd | Information & communication | 2025 |
| Dronescout Ltd | Professional & scientific | 2024 |
| Dronue Ltd | Professional & scientific | 2024 |
| Drsconstructions Limited | Construction | 2025 |
| Drum Unit Recordings Ltd | Administrative & support | 2021 |
| Drun Ltd | Real estate | 2021 |
| Dryadic Ltd | Information & communication | 2025 |
| DS LDN Supplies Limited | Wholesale & retail | 2024 |
| DSB Commercial Cleaning Services Ltd | Administrative & support | 2025 |
| Dscvr Creative CIC | Information & communication | 2023 |
| Dsdesigns Ltd | Manufacturing | 2024 |
| Dshl Enterprises Limited | Real estate | 2024 |
| DSS (Medical) Limited | Health & social care | 2023 |
| Dssn Ltd | Real estate | 2021 |
| DTH Consultancy Services Limited | Wholesale & retail | 2013 |
| DUCKS2WATER (Cedar Park) LLP | | 2024 |
| DUCKS2WATER (High Wycombe) LLP | | 2023 |
| DUCKS2WATER Ltd | Professional & scientific | 2025 |
| Duct Care Limited | Professional & scientific | 2015 |
| Ducting Online Limited | Financial services | 2010 |
| Dudra Properties Ltd | Real estate | 2024 |
| Dukes Wood Building Limited | Construction | 2016 |
| Dumaxa Accountancy Ltd | Professional & scientific | 2018 |
| Duncan Bailey Kennedy LLP | | 2017 |
| Dunheved Productivity Limited | Professional & scientific | 2005 |
| Dunkeld House (Management) Company Limited | Households | 1975 |
| Dunlop Consulting Ltd | Professional & scientific | 2024 |
| Dunton Green Management Company (NO.1) Limited | Extraterritorial | 2005 |
| Dunton Green Management Company (NO.2) Limited | Extraterritorial | 2005 |
| DUO Global Consulting Limited | Professional & scientific | 2014 |
| DUO HW Limited | Households | 2018 |
| Duplex Communications Ltd | Extraterritorial | 2025 |
| Duplex Corporate Communications Limited | Wholesale & retail | 2006 |
| Duplion Limited | Administrative & support | 2015 |
| Durdledoorlettings Ltd | Hospitality | 2025 |
| Durley DM Limited | Administrative & support | 2015 |
| Durston Pottery Tools Limited | Manufacturing | 2024 |
| Duss Environmental Engineering Limited | Professional & scientific | 2023 |
| Dustbusters Cleaning Limited | Administrative & support | 2009 |
| Dvcm Consultancy Limited | Information & communication | 2018 |
| Dwell Well Cpsj Ltd | Construction | 2026 |
| DWG Advisory Ltd | Professional & scientific | 2026 |
| Dwjc Consultancy Ltd | Administrative & support | 2020 |
| Dygital Ltd | Information & communication | 2024 |
| Dyko Ltd | Professional & scientific | 2026 |
| Dynamic Home Improvements Limited | Construction | 2020 |
| Dynamics Vision Consultancy Ltd | Real estate | 2019 |
| Dynaze Consultancy Limited | Information & communication | 2022 |
| Dynma Limited | Wholesale & retail | 2025 |
| Dyno Performance Services Limited | Manufacturing | 2012 |
| DZ Quantity Surveying Ltd | Professional & scientific | 2020 |
| E & C Partnership LLP | | 2006 |
| E Build Brickwork and Construction Ltd | Administrative & support | 2017 |
| E Custom Trading Ltd | Wholesale & retail | 2022 |
| E Fitzgerald Properties Ltd | Real estate | 2010 |
| E Group Property Services Ltd | Real estate | 2004 |
| E J Churchill Group Ltd. | Arts & recreation | 2020 |
| E J Churchill Limited | Arts & recreation | 1989 |
| E Technologia Ltd | Wholesale & retail | 2025 |