| Delta Car GX Limited | Transport & logistics | 2017 |
| Delta Chiller Services Ltd | Energy | 2024 |
| Delta Construct (Project Services) Limited | Construction | 2014 |
| Delta-T Consulting Ltd | Professional & scientific | 2014 |
| Deltacomgroup Engineering UK Ltd | Manufacturing | 2022 |
| Deltamind Solutions Limited | Extraterritorial | 2022 |
| Deluxe Roofing Contractors & Suppliers Limited | Construction | 1997 |
| Denaz Limited | Wholesale & retail | 2021 |
| Denegarden Properties Limited | Real estate | 2025 |
| Denham Green Associates Limited | Administrative & support | 2013 |
| Denis KM Ltd | Construction | 2026 |
| Denise ELA Maley Ltd | Health & social care | 2016 |
| Dennis Build Ltd | Construction | 2024 |
| Denny Foods Ltd | Wholesale & retail | 2023 |
| Denport Utilities Ltd | Construction | 2025 |
| Dentin Ltd | Health & social care | 2024 |
| Dentonovo Ltd | Health & social care | 2014 |
| Denture World Limited | Health & social care | 2022 |
| DEO Consulting Limited | Professional & scientific | 2000 |
| Derek Barrett Design Ltd | Manufacturing | 2017 |
| Dermalase Bucks Ltd | Health & social care | 2017 |
| Dermica Laboratoires UK Ltd | Wholesale & retail | 2018 |
| Deryn Holland Associates Limited | Administrative & support | 2009 |
| DES Catering (Brixton) Ltd | Hospitality | 2019 |
| DES Projects Ltd | Construction | 2016 |
| Desantospubs Ltd | Hospitality | 2025 |
| Desboro Consultants Ltd | Professional & scientific | 2009 |
| Desborough Foods Ltd | Hospitality | 2026 |
| Desborough Industrial Park Management Co. Limited | Real estate | 1986 |
| Desborough Park Road Management Company Limited | Households | 1992 |
| Deseret U.K. Trustco Unlimited | Professional & scientific | 2006 |
| Design by Will Rose Ltd | Professional & scientific | 2023 |
| Design to Thrive Ltd | Professional & scientific | 2022 |
| Designed-Flue Ltd | Wholesale & retail | 2024 |
| Designer Builders & Renovations Limited | Construction | 2012 |
| Designerfist Ltd | Professional & scientific | 2026 |
| DESIGNS2WORK Ltd | Construction | 2008 |
| Desired Scents UK Ltd | Wholesale & retail | 2026 |
| Detail Kings HW Ltd | Wholesale & retail | 2020 |
| Detail Personnel Care Limited | Health & social care | 2018 |
| Detail Personnel Limited | Administrative & support | 2015 |
| Detawo Global Investments Limited | Information & communication | 2025 |
| Developer Consultancy Services Ltd | Construction | 2020 |
| Devereux Chauffeur Services Ltd. | Transport & logistics | 2016 |
| Devil’S Coffee Ltd | Manufacturing | 2021 |
| Devondale Electrical Distributors Limited | Wholesale & retail | 1981 |
| Devondale Holdings Limited | Wholesale & retail | 2013 |
| Devonport Services Limited | Real estate | 2025 |
| Devtrox Ltd | Wholesale & retail | 2025 |
| DEW Dance Ltd | Arts & recreation | 2023 |
| Dewan Properties Ltd | Real estate | 2021 |
| Dewcam Ltd | Information & communication | 2019 |
| DEX International Limited | Financial services | 2008 |
| Dexter & Co.,(High Wycombe)Limited | | 1920 |
| Dexter Accountants Limited | Professional & scientific | 2025 |
| Dexter Novac Investments Limited | Real estate | 2015 |
| Dexter Novac Limited | Construction | 2016 |
| Dexter Novac Services Ltd | Construction | 2019 |
| Dexteritypro Ltd | Wholesale & retail | 2025 |
| Dezant Consulting Ltd | Information & communication | 2014 |
| DFB Wholesale Ltd | Wholesale & retail | 2025 |
| DFF Construction Limited | Construction | 2016 |
| DG Action Design Limited | Administrative & support | 2026 |
| DH Landscapes and Sons Limited | Professional & scientific | 2026 |
| DHA Construction Limited | Construction | 2025 |
| DHA Consultancy Ltd | Administrative & support | 2022 |
| Dhamaka Catering Limited | Hospitality | 2020 |
| Dhami Estates Limited | Real estate | 2020 |
| DHB Consulting Limited | Information & communication | 2009 |
| DHD Accounting Limited | Professional & scientific | 2012 |
| DHD Ventures Limited | Other services | 2018 |
| Dhot Build and Maintenance Ltd | Construction | 2025 |
| DHP Marketing Ltd | Professional & scientific | 2020 |
| DIAL4 Properties Ltd | Real estate | 2023 |
| DIAL4PANELS Ltd | Wholesale & retail | 2015 |
| Diamond Auto Repairs Ltd | Wholesale & retail | 2022 |
| Diamond Back Tattoo Ltd | Other services | 2012 |
| Diamond Communications (UK) Limited | Information & communication | 1998 |
| Diapente Ltd | Information & communication | 2014 |
| Dibba Enterprises Limited | Wholesale & retail | 2020 |
| Dibley Phillips Limited | Information & communication | 2008 |
| Dickinson Tree Company Ltd | Professional & scientific | 2019 |
| Dictalogic Limited | Information & communication | 2018 |
| Diemkay Property Services Ltd | Construction | 2022 |
| Diera Interiors Ltd | Wholesale & retail | 2016 |
| Diera Joinery Ltd | Manufacturing | 2014 |
| Different Gravy Club Ltd | Manufacturing | 2026 |
| Differentia Consulting Ltd. | Information & communication | 2002 |
| Difflex Ltd | Information & communication | 2015 |
| DIG Global Media Ltd | Professional & scientific | 2017 |
| DIG Online Ltd | Professional & scientific | 2011 |
| Digaxa Ltd | Administrative & support | 2021 |
| Digi Crafters Ltd | Professional & scientific | 2024 |
| Digital Swim School Limited | Education | 2025 |
| Digital Systems and Arkitektures Limited | Information & communication | 2015 |
| Digital Thingz Ltd | Manufacturing | 2017 |
| Digital-First Retail Limited | Wholesale & retail | 2018 |
| Digitalgigs Limited | Information & communication | 2019 |
| Digitec Communications Ltd | Information & communication | 2002 |
| Digitegrity Limited | Information & communication | 2019 |