| Smoke Shafts and Risers Ltd | Construction | 2025 |
| Social Care Network Solutions Limited | Information & communication | 1996 |
| Social Link Travel Ltd | Administrative & support | 2025 |
| Soft Scrub Ltd | Administrative & support | 2025 |
| Solarium Shutters and Blinds Ltd | Construction | 2026 |
| Solid Works Construction Limited | Construction | 2025 |
| Some Delish Ltd | Hospitality | 2023 |
| Sorted Repairs Done Right Ltd | Construction | 2024 |
| Sound Secure (UK) Ltd | Manufacturing | 2011 |
| SP Ceilings & Partitions Ltd | Construction | 2012 |
| Space Cassette Events Ltd | Arts & recreation | 2019 |
| Spadechoice Limited | Other services | 2006 |
| Sparkleen Services Limited | Real estate | 2021 |
| Specialised Builders Ltd | Administrative & support | 2019 |
| Specialised Driveways Ltd | Administrative & support | 2019 |
| Specialist Care Developments Ltd | Construction | 2012 |
| Spencerpg Limited | Construction | 2020 |
| Splicetec Ltd | Information & communication | 2023 |
| Split N Polish Limited | Other services | 2002 |
| Spodden Mill Ltd | Real estate | 2018 |
| Sports Strategy & Insights Consultancy Limited | Professional & scientific | 2020 |
| Spring Valley Childrens Care Home Ltd | Health & social care | 2023 |
| SS Apparel Ltd | Wholesale & retail | 2025 |
| SS Capital Investments Limited | Professional & scientific | 2021 |
| SSR Utilities Limited | Energy | 2025 |
| ST George's Commercials Limited | Hospitality | 2008 |
| St-Sample Health Care Services Ltd | Health & social care | 2022 |
| Stack ME UP Limited | Hospitality | 2025 |
| Star Courier Distribution Ltd | Transport & logistics | 2019 |
| Stepping Stone Projects | Other services | 1991 |
| Sterling Packaging Limited | Transport & logistics | 2004 |
| Sterling Trade Doors Limited | Wholesale & retail | 2026 |
| Stevens & Sons Ltd | Construction | 2025 |
| Stewart Anders T/A Northern Logistics (UK) Limited | Transport & logistics | 2013 |
| Stockberg Global Ltd | Wholesale & retail | 2019 |
| Stone Healthcare (North West) Ltd | Health & social care | 2018 |
| Stone Pale Properties Limited | Real estate | 2020 |
| Stop Shop Heywood Ltd | Wholesale & retail | 2025 |
| Store 121 Limited | Wholesale & retail | 2024 |
| Stott Estates & Property Management Ltd | Other services | 2024 |
| Stott Estates Ltd | Real estate | 2023 |
| STRAIGHTTOYOURDOOR25 Ltd | Wholesale & retail | 2025 |
| Strawberry Garden Ltd | Wholesale & retail | 2024 |
| Street Furniture Maintenance Ltd | Other services | 2015 |
| Studio Lumina Ltd | Professional & scientific | 2009 |
| Studio Spirit Ltd | Professional & scientific | 2021 |
| Styal Solutions Ltd | Construction | 2003 |
| Styles Spot Ltd | Wholesale & retail | 2025 |
| Subby Support Ltd | Professional & scientific | 2020 |
| Sudservices Limited | Households | 2025 |
| Suilvision Limited | Professional & scientific | 2010 |
| Sultans Grill Limited | Hospitality | 2025 |
| Summit MOT Service Station Ltd | Other services | 2021 |
| Summit Plumbing Services Limited | Construction | 2019 |
| Sunnydale Foods Distribution Ltd | Wholesale & retail | 2016 |
| Sunnyfishchip Ltd | Hospitality | 2024 |
| Sunshine Distribution Ltd | Transport & logistics | 2018 |
| Super Dealz Online Ltd | Wholesale & retail | 2018 |
| Superior Garage Roofs and Doors Limited | Construction | 2024 |
| Superpiston 62 Ltd | Wholesale & retail | 2023 |
| Supplycove Ltd | Wholesale & retail | 2025 |
| Surasooya Limited | Agriculture & fishing | 2021 |
| Sure-Fit Tyres Limited | Wholesale & retail | 2010 |
| Swift Estate Management Ltd | Real estate | 2017 |
| Swift Pack Solutions Ltd | Professional & scientific | 2026 |
| Sylcomm Translation Services Ltd | Professional & scientific | 2026 |
| Synergy Fire Installations Limited | Manufacturing | 2015 |
| Syrinx Payroll Ltd | Administrative & support | 2025 |
| T and N. Siddique Limited | Administrative & support | 2013 |
| T.O.B. (Contractors) Limited | Construction | 1979 |
| Tablegard Limited | Wholesale & retail | 2004 |
| Tate House Limited | Real estate | 2017 |
| TB Roofing Services North West Ltd | Construction | 2025 |
| TCD Consulting Limited | Professional & scientific | 2018 |
| TDN Electrical Engineering Ltd | Professional & scientific | 2026 |
| Teca Building Soluctions Ltd | Construction | 2023 |
| Technical Service Consultants Limited | Manufacturing | 1980 |
| Techno Mobile Repairs Ltd | Other services | 2025 |
| Teelab Services Ltd | Administrative & support | 2019 |
| Teeny Togs Baby Wear Ltd | Extraterritorial | 2016 |
| Tell YA Momma Ltd | Wholesale & retail | 2024 |
| Teqex Ltd | Wholesale & retail | 2013 |
| Textiles Enterprises Corporation Limited | Manufacturing | 1989 |
| TGI Vapours (Heywood) Limited | Wholesale & retail | 2018 |
| Thanu Holdings Limited | Financial services | 2026 |
| THE Armstrong GRP Limited | Professional & scientific | 2024 |
| THE Brown COW Public House Limited | Administrative & support | 2003 |
| THE Churros Guys Limited | Hospitality | 2025 |
| THE Cloud Beauty Salon and Academy Ltd | Education | 2025 |
| THE Coffee Shop (Ashton) Ltd | Hospitality | 2024 |
| THE Cotton Tree Inn Limited | Hospitality | 2024 |
| THE Crime Prevention Unit Ltd | Administrative & support | 2012 |
| THE Damascene Group Limited | Education | 2019 |
| THE Fade Lounge Heywood Ltd | Other services | 2025 |
| THE Fitter's Friend Limited | Manufacturing | 1998 |
| THE Heywood Barbers 0 Ltd | Other services | 2026 |
| THE Maze Manchester Ltd | Hospitality | 2019 |
| THE Mens Room Barber Heywood Limited | Other services | 2021 |
| THE Original Tattooers Arms Limited | Administrative & support | 2006 |
| THE Pines (Heywood) Management Limited | Real estate | 2007 |