| Hexham Mobility Limited | Wholesale & retail | 2025 |
| Hexham Nails 2 Ltd | Other services | 2025 |
| Hexham New Church | Other services | 2014 |
| Hexham Phones Ltd | Wholesale & retail | 2024 |
| Hexham Physio Ltd | Health & social care | 2019 |
| Hexham Pizza House Ltd | Hospitality | 2025 |
| Hexham Pizza NE Ltd | Hospitality | 2025 |
| Hexham Storage Limited | Administrative & support | 2013 |
| Hexham Trailers Limited | Wholesale & retail | 2022 |
| Hexham Tyre & Battery Co.Limited | Wholesale & retail | 1967 |
| Hexham Violin Shop Ltd | Manufacturing | 2024 |
| Hfgh Limited | Professional & scientific | 2024 |
| HH Community Care Limited | Health & social care | 2008 |
| HH Healthcare Limited | Health & social care | 2020 |
| HH Sports Consultancy Limited | Professional & scientific | 2020 |
| High Stonecroft Limited | Real estate | 2026 |
| High Studdon Limited | Administrative & support | 2007 |
| High Warden Farm Limited | Agriculture & fishing | 1997 |
| Higher Ground Allendale | Other services | 2016 |
| Highford Consulting Limited | Professional & scientific | 2025 |
| HK Central Properties Ltd | Real estate | 2019 |
| Hoekhuisje Ltd | Hospitality | 2021 |
| Holistic Land Management Ltd | Real estate | 2024 |
| Holly Court (Hexham) Management Limited | Households | 2005 |
| Hollys Hope Ltd | Education | 2025 |
| Home Farm Management (Newbrough) Limited | Water & waste | 2001 |
| Honeyman Training & Consultancy Limited | Professional & scientific | 2021 |
| Hooray Cakes Limited | Manufacturing | 2011 |
| Horseworks Equine Science Consultancy Ltd | Professional & scientific | 2020 |
| House of S&S Attire Limited | Wholesale & retail | 2021 |
| Howard Snaith Limited | Transport & logistics | 2003 |
| Howie Associates Ltd | Information & communication | 2003 |
| HT3 Transport Ltd | Transport & logistics | 2025 |
| HTS Industrial Two Ltd | Wholesale & retail | 2025 |
| Humble & Clark Legal Services LLP | | 2015 |
| Humshaugh Community Ventures Limited | Wholesale & retail | 2009 |
| Humshaugh Ltd | Hospitality | 2020 |
| Humshaugh NET Zero CIC | Other services | 2020 |
| Hungry Shack International Ltd | Real estate | 2019 |
| Hunter Harvesting Limited | Agriculture & fishing | 2003 |
| Hyco Drinks Limited | Wholesale & retail | 2025 |
| I P B North Tyne Limited | Real estate | 2016 |
| I Rogerson Plumbing & Heating Ltd | Construction | 2019 |
| Iain Kendrew (Joinery & Building) Limited | Construction | 2015 |
| IAN Proctor Sound & Lighting Limited | Other services | 2010 |
| Ibrow Junkie Ltd | Other services | 2016 |
| Idente ( UK ) Ltd | Manufacturing | 2014 |
| IJ Networks Limited | Information & communication | 2008 |
| Imaginatives Group Limited | Professional & scientific | 2015 |
| Imaginatives Latin America Limited | Professional & scientific | 2020 |
| IMV Creative Consulting Ltd | Arts & recreation | 2025 |
| IN a Hurry Ltd | Transport & logistics | 2026 |
| In-House Films Ltd | Information & communication | 2019 |
| In-House Inspired Room Design Ltd | Wholesale & retail | 2003 |
| Incognito Interiors Limited | Wholesale & retail | 2006 |
| Indie Inns Ltd | Hospitality | 2010 |
| Indoor Cooling Limited | Administrative & support | 1997 |
| Infai Ltd | Information & communication | 2025 |
| Innovation Explorer Ltd | Education | 2022 |
| Inox Engineering Ltd | Construction | 2020 |
| Insight Architectural Design Ltd | Professional & scientific | 2018 |
| Insightex Ltd | Professional & scientific | 2024 |
| Instamat UK Ltd | Construction | 2015 |
| Insync Physiotherapy and Sports Injury Clinic Ltd | Health & social care | 2019 |
| Intake Veterinary Services Limited | Professional & scientific | 2002 |
| Integrated Resource Management Limited | Professional & scientific | 2018 |
| International Tax Stamp, Authentication and Traceability Association Limited | Information & communication | 2015 |
| Internet Audit Limited | Information & communication | 2022 |
| IP Development & Planning Limited | Construction | 2022 |
| Isra AG Ltd | Professional & scientific | 2024 |
| Italian Furniture Products Ltd | Wholesale & retail | 2019 |
| J & P Farriers Limited | Agriculture & fishing | 2022 |
| J a Laundry & Cleaning Ltd | Administrative & support | 2026 |
| J B Colman Limited | Health & social care | 2018 |
| J Cotton Agricultural Contractors Limited | Administrative & support | 2006 |
| J Gormley Limited | Construction | 2015 |
| J Holland Ltd | Wholesale & retail | 2021 |
| J K Takeaway Ltd | Hospitality | 2021 |
| J Lees Welding Equipment Services Limited | Manufacturing | 2008 |
| J P B Specialist Cars Limited | Wholesale & retail | 2018 |
| J P Westall Limited | Construction | 2000 |
| J W Pubs NE Ltd | Hospitality | 2025 |
| J.N. Davison (Newcastle) Limited | Real estate | 1965 |
| J.P Poulter NE Ltd | Construction | 2023 |
| J.S. Hubbuck Limited | Wholesale & retail | 1975 |
| J.T. Nixon & Sons Ltd | Agriculture & fishing | 2004 |
| JAI Phone Palace Limited | Other services | 2017 |
| James Ritchie Architect Limited | Construction | 2020 |
| James Tate Consulting Limited | Information & communication | 2013 |
| Jamiesons Laundry Services Ltd | Administrative & support | 2025 |
| Jamsip LLP | | 2018 |
| Jane Fisher Associates Ltd | Professional & scientific | 2013 |
| Japc Limited | Professional & scientific | 2015 |
| Jasper Bows Limited | Professional & scientific | 2014 |
| Jayne Andrews - Marketing & Ideas Consultancy Ltd | Professional & scientific | 2025 |
| JB Colman(Hexham) Limited | Other services | 2022 |
| JB Landscape Contracting Services Limited | Construction | 2004 |
| JD HV Site Management Limited | Professional & scientific | 2020 |
| Jeff Oliver Maintenance Limited | Construction | 2007 |
| Jenny White Locum Services Limited | Professional & scientific | 2018 |