| Emily Jill Dickinson Ltd | Health & social care | 2026 |
| Emperor Products Limited | Wholesale & retail | 2020 |
| Envaan Ltd | Information & communication | 2026 |
| Envirocard Limited | Wholesale & retail | 2022 |
| Envision Marine Ltd. | Professional & scientific | 2003 |
| Epitope Informatics Limited | Professional & scientific | 2000 |
| Equilibrium Environmental Consultants Ltd. | Professional & scientific | 2015 |
| Equine Opportunities Limited | Real estate | 2014 |
| Eris Energy Limited | Financial services | 2021 |
| Errington Reay & Company,Limited | Manufacturing | 1933 |
| ESI RAM Property Ltd | Real estate | 2025 |
| Estek Software Technologies Ltd | Information & communication | 2012 |
| Ethos Nutrition Ltd | Manufacturing | 2022 |
| Etia Properties Ltd | Financial services | 2025 |
| Euro-Inspect Limited | Professional & scientific | 2001 |
| Eurus Renewable Consulting Ltd | Professional & scientific | 2018 |
| Evalutility Limited | Professional & scientific | 2009 |
| Eveagency Limited | Administrative & support | 1998 |
| Event Centre UK Limited | Construction | 2021 |
| Evolve Coaching HQ Ltd | Arts & recreation | 2026 |
| Evolve Global Love Ltd | Health & social care | 2024 |
| Exclusive Residential Limited | Construction | 2015 |
| Exiam Ltd | Wholesale & retail | 2006 |
| Export Solutions North East Limited | Information & communication | 2016 |
| F. E. P. Hexham Ltd | Wholesale & retail | 2011 |
| Fahospitality Limited | Hospitality | 2026 |
| Fairfield Financial Consultants Ltd | Professional & scientific | 2025 |
| Falstone Community Trust Limited | Professional & scientific | 2018 |
| Falstone Schoolrooms Limited | Hospitality | 2003 |
| Families on Track CIC | Education | 2021 |
| Farmtrend Limited | Professional & scientific | 2004 |
| Fawdingtons Garages Limited | Wholesale & retail | 1964 |
| Fawside | Real estate | 2003 |
| FDM Management Solutions Ltd | Professional & scientific | 2019 |
| Fedbyclaire Ltd | Wholesale & retail | 2026 |
| Feer Shaab Ltd | Hospitality | 2015 |
| Fentimans Ltd. | Manufacturing | 1994 |
| Ferguson Fitness HQ Limited | Other services | 2023 |
| Field Force Technologies Limited | Information & communication | 2023 |
| Fieldtech Engineering Ltd | Manufacturing | 2020 |
| FIG the Fish Ltd | Arts & recreation | 2019 |
| Film Safely Limited | Extraterritorial | 2015 |
| Filmbee Coop CIC | Information & communication | 2014 |
| Fineside Limited | Extraterritorial | 2010 |
| Finnegan Transport Ltd | Transport & logistics | 2019 |
| Firefly Consultants Limited | Professional & scientific | 2022 |
| First Square Equipment Ltd | Wholesale & retail | 2005 |
| First Thought (Consultancy) Limited | Professional & scientific | 2003 |
| Fit to Dive Ltd | Professional & scientific | 2020 |
| Fjack Ltd | Wholesale & retail | 2023 |
| Flipnfast Ltd | Hospitality | 2023 |
| Flourish Coaching Ltd | Health & social care | 2025 |
| Fluteland Limited | | 1980 |
| FLY Fishing Nation Media Limited | Manufacturing | 2021 |
| FLY Fishing Nation Syndicate Limited | Administrative & support | 2023 |
| Focal Draw Limited | Information & communication | 2020 |
| Footprint Public Relations Limited | Professional & scientific | 2007 |
| FOR Real Limited | Information & communication | 2024 |
| Forefield Limited | Real estate | 2020 |
| Forensic Pathology Limited | Professional & scientific | 2010 |
| Forum Cinema Hexham Limited | Information & communication | 2007 |
| Fountain Cottage B&B Limited | Hospitality | 2019 |
| Fountain Cottage Cafe Limited | Hospitality | 2019 |
| Fourstones Paper Mill Company Limited | Manufacturing | 1952 |
| Foxtrot Computer Services Limited | Information & communication | 1995 |
| Freedom to Play Ltd | Education | 2022 |
| Freehold 43 Croxteth Road Liverpool Limited | Real estate | 2021 |
| Freestone Limited | Hospitality | 2023 |
| French & Wilder Ltd | Wholesale & retail | 2023 |
| Fresh Meat Club Ltd | Manufacturing | 2023 |
| Frntir Ltd | Information & communication | 2025 |
| From EWE Ltd | Manufacturing | 2025 |
| Funky Chair Interiors Ltd | Other services | 2026 |
| G & a Wallace Engineers Limited | Manufacturing | 2012 |
| G & E Engineering Limited | Professional & scientific | 2013 |
| G Potts Loggin Ltd | Agriculture & fishing | 2013 |
| G T P Mortgage & Financial Services Limited | Financial services | 2012 |
| G. Capstick Timber Limited | Agriculture & fishing | 2007 |
| G.T. Joinery & Property Services Ltd | Construction | 2015 |
| Gables Park Management Company Limited | Real estate | 2001 |
| Gables Park Management Company NO. 2 Limited | Households | 2003 |
| Gaisford Greene Ltd | Administrative & support | 2026 |
| Gala DUE Limited | Real estate | 2006 |
| Gala Quattro Limited | Real estate | 2022 |
| Gala Unity Limited | Real estate | 2001 |
| Galanthus Research Limited | Professional & scientific | 2026 |
| Galen Biomed Limited | Professional & scientific | 2015 |
| Gallina LED Ltd | Wholesale & retail | 2019 |
| GAP Supported Housing Ltd | Hospitality | 2009 |
| Garden House Farm Hexham Limited | Construction | 2025 |
| Garden House Farm Investments Limited | Real estate | 2025 |
| Gareth James Estate Limited | Information & communication | 2021 |
| GD Power Limited | Professional & scientific | 2021 |
| Gemelli Travel Ltd | Administrative & support | 2025 |
| Genark Limited | Professional & scientific | 2025 |
| Geoff Steven & Sons Limited | Health & social care | 2010 |
| George Bernard Shaw Ltd | Transport & logistics | 1998 |
| George Gamble Limited | Construction | 2024 |
| George Stephenson Double Glazing Ltd | Construction | 2017 |
| George Vyner Holdings Limited | Real estate | 2016 |