| Virtual School Limited | Education | 2025 |
| Vision IQ Ltd | Extraterritorial | 2007 |
| Visit Bernicia Limited | Information & communication | 2017 |
| Visit Lothian Limited | Information & communication | 2018 |
| Vita-Rhize UK Ltd | Wholesale & retail | 2022 |
| Viteology Limited | Health & social care | 2022 |
| Voba (UK) Limited | Professional & scientific | 2005 |
| VVO 100 Limited | Administrative & support | 2016 |
| VVO 101 Limited | Professional & scientific | 2017 |
| VWX Automotive Limited | Wholesale & retail | 2017 |
| VY Property Limited | Real estate | 2024 |
| W.J. Scott Ltd | Agriculture & fishing | 2004 |
| WAG and Company North East Friendship Dogs | Health & social care | 2015 |
| Walhouse Surveyors Limited | Other services | 2018 |
| Walton Logging Limited | Agriculture & fishing | 1999 |
| Walwick Estate Group Ltd | Hospitality | 2020 |
| Wark Estates Limited | Construction | 2007 |
| Warren Farm (Powys) Limited | Agriculture & fishing | 1989 |
| Wastebusters North East Ltd | Water & waste | 2004 |
| Watchmaker Limited | Real estate | 2024 |
| Watson GSM Clear View Ltd | Administrative & support | 2025 |
| Watsons GSM Moss & Gutters Ltd | Administrative & support | 2025 |
| Waverley Partners Limited | Information & communication | 2025 |
| WAX Free EAR Care Ltd. | Health & social care | 2024 |
| WBC Trade Ltd | Wholesale & retail | 2022 |
| WBE Holdings Limited | Financial services | 2023 |
| WBE Limited | Professional & scientific | 2013 |
| WE ARE Frankie Limited | Other services | 2019 |
| Wecan - WE Enable Children With Additional Needs | Health & social care | 2007 |
| Wenekt Limited | Information & communication | 2026 |
| Wentworth Northern Properties Limited | Real estate | 1992 |
| West Chirnells Limited | Transport & logistics | 2022 |
| Westbrooke Residents Limited | Households | 2011 |
| Westland Medical and Health Consultancy Services " Ltd | Health & social care | 2023 |
| Westoe Vets Limited | Administrative & support | 2012 |
| Westwater Angling Limited | Agriculture & fishing | 1999 |
| What Fresh Hell Books Limited | Information & communication | 2023 |
| Whisper Aesthetics Ltd | Health & social care | 2022 |
| Whispering Gibbon Ltd | Information & communication | 2011 |
| Whispers Hairdressing Limited | Other services | 2009 |
| Whitchester Farm Limited | Agriculture & fishing | 1975 |
| White Rabbit Site Investigation Ltd | Construction | 2024 |
| Whitewood Properties Limited | Real estate | 2020 |
| Whitfield Farms Limited | Agriculture & fishing | 2012 |
| Wild About Adventure Ltd | Education | 2015 |
| Wild Northumbrian Ltd | Hospitality | 2018 |
| Wildblood Farm Ltd. | Agriculture & fishing | 2025 |
| Wilf Beck Enterprises Limited | Hospitality | 2016 |
| William Rutherford & Sons (Holdings) Limited | Water & waste | 2003 |
| William Wood Watches Ltd | Wholesale & retail | 2017 |
| Williamsons Craig LLP | | 2016 |
| Willow Estimating Ltd | Professional & scientific | 2012 |
| Wilson Business Solutions Limited | Professional & scientific | 2005 |
| Wilson DW Plumbing and Heating Ltd | Energy | 2026 |
| Wilson Heat Ltd | Construction | 2006 |
| Win-Elite Ltd | Wholesale & retail | 2010 |
| WL Beattie & Sons Ltd | Agriculture & fishing | 2014 |
| WMH Quality Catering Ltd | Hospitality | 2022 |
| Wonderful Spaces Ltd | Wholesale & retail | 2025 |
| Wonderloft Limited | Arts & recreation | 2024 |
| Wooden Star Cottages Ltd | Hospitality | 2018 |
| Woodhouse Consulting Services Limited | Information & communication | 2015 |
| Woodman Farming | Administrative & support | 2011 |
| Woodside Project Services Limited | Professional & scientific | 2007 |
| Woodyfuel Ltd | Wholesale & retail | 2017 |
| Word & Smyth Ltd. | Professional & scientific | 2022 |
| Words Worldwide Ltd. | Information & communication | 1998 |
| Work Secure Ltd | Information & communication | 2021 |
| WR Paddock Limited | Construction | 2016 |
| Wrph Holdings Limited | Construction | 2019 |
| WTF Consulting Ltd | Professional & scientific | 2022 |
| Wylam Garage Limited | Wholesale & retail | 1977 |
| Wyse Internet Ltd | Information & communication | 2008 |
| Xiphos Investment Research (U.K.) Ltd. | Information & communication | 2002 |
| Xiphos Limited | Professional & scientific | 2017 |
| Xyst Limited | Construction | 2018 |
| YCS (Hexham) Limited | Administrative & support | 2011 |
| YCS Construction Limited | Construction | 2008 |
| Youngs RPS Limited | Real estate | 2014 |
| Your Optimal Performance Ltd | Health & social care | 2019 |
| Youth Self-Empowerment CIC | Professional & scientific | 2024 |
| Zebra Wealth Management Ltd | Financial services | 2021 |
| Zest Visuals Ltd | Information & communication | 2009 |
| Zubazaar Limited | Information & communication | 2009 |
| Zyka Boutique Indian Restaurant Ltd | Hospitality | 2013 |