| Mobility L.S Ltd | Wholesale & retail | 2022 |
| Mobius Media Limited | Information & communication | 2012 |
| Modifeye Limited | Other services | 2023 |
| Moes Kitchen Ltd | Hospitality | 2018 |
| Molescroft Healthcare Limited | Health & social care | 2015 |
| Molescroft Holdings Limited | Health & social care | 2018 |
| Molescroft Nursing Home (Holdings) Limited | Health & social care | 1997 |
| Molly Blakey Design Limited | Professional & scientific | 2026 |
| Moore Property Solutions Limited | Administrative & support | 2020 |
| Morfa Retreats Limited | Real estate | 2026 |
| Mortgages Made Easy (Hull) Limited | Financial services | 2008 |
| Motor Depot Limited | Wholesale & retail | 2001 |
| MPP Consultants Limited | Professional & scientific | 2026 |
| MS3 Networks Limited | Information & communication | 2012 |
| Mucklow Hill Developments Limited | Construction | 2024 |
| Multichannel Enterprises Ltd | Administrative & support | 2016 |
| Music With ME Limited | Education | 2026 |
| My Barber (Hull) Limited | Other services | 2024 |
| My D3N Limited | Real estate | 2018 |
| Mytaxcloud Limited | Professional & scientific | 2017 |
| N&N Waste Services Ltd | Professional & scientific | 2026 |
| Nature & Steel Bespoke Ltd | Wholesale & retail | 2025 |
| Neill & Brown (Exports) Limited | Professional & scientific | 1976 |
| Neill & Brown (Shipping) Limited | Transport & logistics | 1979 |
| Neill & Brown Global Logistics Group Limited | Professional & scientific | 1988 |
| Neill & Brown Limited | Transport & logistics | 1939 |
| Neill and Brown (S.E.T.S.) Limited | Professional & scientific | 1981 |
| Nelthorpe Arms Public House Limited | Hospitality | 2023 |
| NET Expectations Limited | Information & communication | 2006 |
| New Inn Leven Limited | Hospitality | 2016 |
| Newland Garage Limited | Wholesale & retail | 2015 |
| Next Step Hub Ltd | Transport & logistics | 2025 |
| Nick Allix Editing Limited | Information & communication | 2014 |
| Nick Rennardson Limited | Information & communication | 2012 |
| Nightingale Care Assistance Ltd | Health & social care | 2025 |
| Nikvar Estates Limited | Construction | 2025 |
| Nilpeter Limited | Manufacturing | 1989 |
| NLD Management Limited | Arts & recreation | 2021 |
| NO4 Consultancy Limited | Professional & scientific | 2025 |
| Norris Ltd | Real estate | 2022 |
| North Doorway Limited | Financial services | 2016 |
| North East Fisheries Limited | Extraterritorial | 2014 |
| North Star Technical Consulting Ltd | Information & communication | 2014 |
| Northern Lights Drama Limited | Arts & recreation | 2015 |
| Northfield Business Services Limited | Professional & scientific | 2008 |
| Northwood Estates (Hessle) Limited | Agriculture & fishing | 2005 |
| Nothing BUT Limited | Wholesale & retail | 2009 |
| Novelty Wood Imports Limited | Wholesale & retail | 2024 |
| NS Joinery & Construction Ltd | Construction | 2014 |
| NU Sigma Enterprises Limited | Real estate | 2017 |
| Number 10 Trading Ltd | Financial services | 2026 |
| Oakbridge Retirement Villages (Chorley) Ltd. | Construction | 2005 |
| Oakbridge Retirement Villages LLP | | 2006 |
| Oakleaf Landscapes (Hull) Limited | Administrative & support | 2014 |
| Ocean Dawn Fishing LLP | | 2012 |
| OCS Investments (Hull) Ltd | Real estate | 2018 |
| Off-Site Construction Services Ltd | Construction | 2022 |
| Officegood Limited | Wholesale & retail | 1990 |
| OJG Renewables Ltd | Manufacturing | 2026 |
| Olune Ltd | Wholesale & retail | 2026 |
| ON Road Properties Limited | Real estate | 2008 |
| One Stop Bazaar Ltd | Wholesale & retail | 2024 |
| Onix Property Group Ltd | Real estate | 2026 |
| Onpoint Software Limited | Information & communication | 2018 |
| Onward Investment Limited | Agriculture & fishing | 2010 |
| Onyx Capital Holdings Ltd | Financial services | 2026 |
| Onyx Medica Limited | Real estate | 2015 |
| Opticoms Solutions Ltd | Information & communication | 2024 |
| Optima PT Limited | Health & social care | 2023 |
| OPTIMUM3 Personal Training Ltd | Health & social care | 2017 |
| Orange Canvas Limited | Information & communication | 2011 |
| Orbital IT Limited | Other services | 2009 |
| Orion Screen Process Limited | Manufacturing | 1984 |
| OUR Imagination Station Ltd | Arts & recreation | 2023 |
| Oval Retail Limited | Wholesale & retail | 2025 |
| Oxtoby Accommodation Limited | Real estate | 2003 |
| Ozone Health Ltd | Information & communication | 2022 |
| P & M Hall Services Limited | Hospitality | 2016 |
| P Squared Limited | Information & communication | 2015 |
| P&E JR Design Ltd | Professional & scientific | 2018 |
| P.T. Joinery Limited | Construction | 2003 |
| PA Contract Services Limited | Construction | 2022 |
| PA Ladieswear Limited | Wholesale & retail | 2023 |
| Pacha Homes Limited | Real estate | 2017 |
| Pacs Holdings Limited | Financial services | 2025 |
| Pampered Pups (Hull) Ltd | Other services | 2025 |
| PAN & Co. Accountants Ltd | Professional & scientific | 2023 |
| Pandora Properties Plymouth LLP | | 2011 |
| Paoli Consulting Ltd | Professional & scientific | 2025 |
| Paperclipped Properties Limited | Real estate | 2022 |
| Paragon Accounts Limited | Administrative & support | 2025 |
| Paragon Plumbing and Heating Ltd | Construction | 2015 |
| Paramount Engineering Design Ltd | Professional & scientific | 2014 |
| Parkburn Estates Limited | Real estate | 2025 |
| Patchell Property Renovations Ltd | Real estate | 2024 |
| Paul M Jensen Limited | Financial services | 2021 |
| Peables Limited | Information & communication | 2017 |
| Penrose Sustainability Limited | Other services | 2025 |
| Pepper Rose Properties Limited | Real estate | 2025 |
| Permaseal (UK) Limited | Construction | 2010 |