| EKA Gardening Limited | Administrative & support | 2020 |
| Ekins Builders Limited | Construction | 2004 |
| Ekins of Hertford Limited | Real estate | 2009 |
| Electric Mayonnaise Ltd | Professional & scientific | 2018 |
| Electrim Ltd | Manufacturing | 2022 |
| Electroid Ltd | Other services | 2010 |
| ELEMENT3 Software Limited | Information & communication | 2010 |
| Elevate Capital Alliance Ltd | Financial services | 2025 |
| Elevated Trading (UK) Limited | Health & social care | 2018 |
| Elise Consulting Services Ltd | Professional & scientific | 2015 |
| Elite Care 24 Ltd | Administrative & support | 2026 |
| Elite Drivers Hertfordshire Ltd | Other services | 2015 |
| Elite Garage Transformations Ltd | Construction | 2024 |
| Elite Home Transformatons Limited | Construction | 2019 |
| Elite Recycling Machinery Ltd | Water & waste | 2002 |
| Elite Recycling Solutions Limited | Water & waste | 2007 |
| Elite Travel Services Limited | Administrative & support | 2016 |
| Elite Ventilation Engineering Limited | Construction | 2019 |
| Elixir Fragrance Limited | Wholesale & retail | 2024 |
| Ellbe Clothing Ltd | Wholesale & retail | 2026 |
| Elle & Sons Limited | Hospitality | 2019 |
| Ellevate Studios Ltd | Education | 2024 |
| Ellie Higgins Ltd | Professional & scientific | 2026 |
| Elliott James Homes Ltd | Construction | 2020 |
| ELM Cleaning Ltd | Administrative & support | 2020 |
| Elstow Road Management Co. Limited | Households | 2001 |
| Elstree Plumbers Limited | Construction | 2003 |
| Elton Court Residents Association Limited | Households | 1984 |
| Elton Park Management Ltd | Households | 1997 |
| Elucidate Housing Limited | Real estate | 2024 |
| Elycia-Marie Art Ltd | Wholesale & retail | 2024 |
| Elyian Investments Limited | Administrative & support | 2019 |
| Elysium Mortgages Limited | Financial services | 2020 |
| Emco Group Limited | Wholesale & retail | 1991 |
| Emco Holdings Limited | Real estate | 2006 |
| Emcolite Limited | Extraterritorial | 1999 |
| Emcovent Limited | Extraterritorial | 1998 |
| EME (Electronic & Mechanical Engineering) Limited | Manufacturing | 1974 |
| Emerging Markets Group Limited | Financial services | 2000 |
| Emerging Markets Limited | Health & social care | 2000 |
| EMG (IM) Limited | Financial services | 2000 |
| Emgie Limited | Construction | 2021 |
| Emico SD Limited | Administrative & support | 2015 |
| Emico Service Management Ltd | Information & communication | 2005 |
| EMM Marine Ltd | Financial services | 2025 |
| Empowered Empire Ltd | Manufacturing | 2015 |
| Emvs Limited | Hospitality | 2016 |
| Enable Software Limited | Information & communication | 2020 |
| Enactor (US) Limited | Extraterritorial | 2015 |
| Enactor International Limited | Extraterritorial | 2015 |
| Enactor Limited | Information & communication | 2005 |
| Enactor on Demand Limited | Extraterritorial | 2014 |
| Enactor Software Limited | Extraterritorial | 2015 |
| Enagh Construction Ltd | Professional & scientific | 2012 |
| Enclave Mews (London EC1) Management Company Limited | Households | 2000 |
| Endz Ltd | Wholesale & retail | 2013 |
| Energysave Electrical Ltd | Construction | 2010 |
| Engage by Becollaboration Ltd | Professional & scientific | 2018 |
| Engineering Innovation Ltd | Professional & scientific | 2024 |
| Enlight Collective Ltd | Health & social care | 2015 |
| Enosis Investments Limited | Financial services | 2025 |
| Ensingen Advisory Limited | Professional & scientific | 2013 |
| Enterprise Care Consulting Limited | Real estate | 2013 |
| Enterprise Commercial Limited | Real estate | 2022 |
| Enterprise Lettings Limited | Real estate | 2014 |
| Entire Building Solutions Limited | Administrative & support | 2012 |
| Enviropallets Ltd | Other services | 2020 |
| EOH Europe Limited | Information & communication | 2020 |
| Epping Solutions Ltd | Construction | 2017 |
| Eprr Systems Ltd | Professional & scientific | 2023 |
| Epsom Builders Limited | Construction | 1991 |
| Epsom Salts Ltd | Wholesale & retail | 2025 |
| EPT Contractors Ltd | Construction | 2025 |
| EQ Hosting Ltd | Information & communication | 2020 |
| Equinox Planning and Development Limited | Construction | 2019 |
| Erdm Services Limited | Construction | 2024 |
| Eren Ayla Limited | Real estate | 2023 |
| Eska Board UK Limited | Wholesale & retail | 1986 |
| Esque Films Ltd. | Arts & recreation | 2023 |
| Esquire Male Grooming Limited | Other services | 2013 |
| Essex Solar Solutions Limited | Construction | 2011 |
| Essex Telecom Solutions Limited | Construction | 2021 |
| Essosa Limited | Information & communication | 2023 |
| Estrellita Properties Limited | Real estate | 1964 |
| Esvr Energy Limited | Extraterritorial | 2025 |
| Eternal Pioneers Ltd | Information & communication | 2025 |
| Ethan & James Holdings Ltd | Financial services | 2024 |
| Ethan Oliver Construction Ltd | Professional & scientific | 2020 |
| Eureka Afro-Caribbean Market Ltd | Other services | 2026 |
| Eureka Care Services Limited | Administrative & support | 2017 |
| Eureka Vending Ltd | Hospitality | 2026 |
| Euro Fleet Sales Limited | Wholesale & retail | 2016 |
| Europe Analytica Limited | Information & communication | 1999 |
| European Asset Finance Limited | Financial services | 2001 |
| European Ventilation Hygiene Association Limited | Other services | 1999 |
| Event Screens Limited | Administrative & support | 2019 |
| Ever Thing Farm Ltd | Agriculture & fishing | 2024 |
| Evergood Associates Ltd | Health & social care | 2003 |
| Evergood Money Limited | Financial services | 2018 |
| Evergood Property Limited | Real estate | 2018 |