| Ellis Real Estate Ltd | Real estate | 2025 |
| ELM Land Limited | Real estate | 2016 |
| Elma IT Solutions Ltd | Information & communication | 2016 |
| Elmfield Gardens North Limited | Households | 2004 |
| Elmhurst (Edgbaston) Ltd | Real estate | 2015 |
| ELT Tech Ltd | Administrative & support | 2024 |
| Elvicta Consulting Ltd. | Construction | 2012 |
| Elvis Drive Ltd | Transport & logistics | 2015 |
| Emark Electrical Services Ltd | Construction | 2014 |
| Embrace Manufacturing Ltd | Manufacturing | 2026 |
| Emerald UK Properties Limited | Real estate | 2023 |
| Emerging Resources Ltd | Financial services | 2023 |
| Emily Rose Framing Limited | Arts & recreation | 2025 |
| Emily's Kitchen London Limited | Hospitality | 2019 |
| Emma Billingham Consulting Ltd | Professional & scientific | 2022 |
| Emma Fretwell Animals and Chiropractic Services Limited | Administrative & support | 2009 |
| Emma Telford Textile Conservator Ltd | Manufacturing | 2010 |
| Emma Virtual Assistance Ltd | Administrative & support | 2025 |
| Emmaus Global Ltd | Professional & scientific | 2019 |
| EMS Technical Services Limited | Energy | 2012 |
| EN Housing Ltd | Real estate | 2022 |
| EN Steak Birmingham Ltd | Hospitality | 2022 |
| EN Steak Hereford Ltd | Hospitality | 2024 |
| Enbarr Business Resilience and Integration Consultancy Limited | Professional & scientific | 2014 |
| Encompass IC Ltd | Professional & scientific | 2019 |
| Encorra Ltd. | Manufacturing | 2015 |
| Endeavour Finishes Ltd | Construction | 2019 |
| Ending Loneliness Community Interest Company | Other services | 2018 |
| Energy WON UK Limited | Construction | 2013 |
| Englands Gate Limited | Hospitality | 1997 |
| Enhardt Group Holdings Ltd | Financial services | 2025 |
| Ennis Caravans Limited | Wholesale & retail | 1993 |
| ENS Investment Ltd | Real estate | 2019 |
| Ensco 928 Limited | Arts & recreation | 2012 |
| Entangled Mercury Ltd. | Information & communication | 2025 |
| Entwood Living Ltd | Real estate | 2025 |
| Environmental Control Services Ltd | Manufacturing | 2024 |
| Environmental Management & Services Limited | Energy | 2008 |
| Environmental Management Solutions Limited | Professional & scientific | 2003 |
| Envitrol Ltd | Extraterritorial | 2023 |
| Epcs Global Limited | Professional & scientific | 2023 |
| Epic Customs Limited | Wholesale & retail | 2022 |
| Epic Global Group Limited | Construction | 2017 |
| Epicure Events Ltd | Hospitality | 2022 |
| Equigreen Limited | Other services | 2022 |
| Equine Resources UK Limited | Agriculture & fishing | 2009 |
| Equity Management Limited | Real estate | 2021 |
| ER Arts CIC | Professional & scientific | 2019 |
| Erda Developments Ltd | Real estate | 2020 |
| Erebus UK Ltd | Public administration | 2008 |
| Erika Technology Ltd | Information & communication | 2020 |
| ERN Investments Ltd | Real estate | 2022 |
| Ernesty One Ltd | Real estate | 2020 |
| Erop Communications Ltd | Information & communication | 2018 |
| Errand Studio Ltd | Professional & scientific | 2019 |
| ESC Trading Company Limited | Wholesale & retail | 2017 |
| Escape Hereford Limited | Other services | 2016 |
| Esher Estates Limited | Real estate | 1904 |
| Esjo Limited | Financial services | 2026 |
| ESP Hereford Limited | Professional & scientific | 2017 |
| Eternalove Ltd | Real estate | 2022 |
| Etherington's Autos Ltd | Wholesale & retail | 2024 |
| ETL Bidco Limited | Financial services | 2020 |
| ETL Midco Limited | Financial services | 2020 |
| ETL Parentco Limited | Financial services | 2020 |
| ETL Systems Limited | Manufacturing | 2003 |
| Eumar Technology Limited | Manufacturing | 1985 |
| Eunyxus Ltd. | Administrative & support | 2024 |
| Euro FUN Park Limited | Extraterritorial | 2005 |
| Euro Team GB Spedition Ltd | Transport & logistics | 2023 |
| Eurogrind Manufacturing Limited | Manufacturing | 2018 |
| Euston Park Management Limited | Real estate | 2004 |
| EV Vish Limited | Wholesale & retail | 2024 |
| Evangeline's Emporium Ltd | | 2009 |
| Evans & Evans Homes Ltd | Construction | 2025 |
| Evans Builders Ltd | Construction | 2022 |
| Evans Farm and Country Supplies Ltd | Wholesale & retail | 1993 |
| Evans Gray Consulting Limited | Professional & scientific | 2023 |
| Evans Gray Group Ltd | Financial services | 2024 |
| Evans Gray Property Limited | Real estate | 2022 |
| Evelyn Holdings Ltd | Financial services | 2022 |
| Eventera AV Ltd | Administrative & support | 2023 |
| Events by Dough Limited | Hospitality | 2026 |
| Evergreen Shutters Limited | Manufacturing | 2017 |
| Every Gift Counts Ltd | Administrative & support | 2025 |
| Evlb Limited | Arts & recreation | 2021 |
| Evoke Property Ltd | Real estate | 2019 |
| Evolution Engineering HFD Ltd | Manufacturing | 2019 |
| Evolve Vape Store Limited | Wholesale & retail | 2024 |
| Ewis (UK) Limited | Other services | 2012 |
| Ewyas Harold United Football Club Limited | Arts & recreation | 2009 |
| Excalibur Sports Limited | Manufacturing | 2018 |
| Execpm Limited | Real estate | 2016 |
| Exenergy Limited | Construction | 2009 |
| Exium (UK) Limited | Manufacturing | 2009 |
| Experience Ukraine Ltd | Administrative & support | 2017 |
| Express Plumbing Distributors Limited | Wholesale & retail | 1983 |
| Extension Design Drawings Ltd | Professional & scientific | 2024 |
| Extrogroup Ltd | Financial services | 2023 |
| Eyehealth Solutions Limited | Health & social care | 2014 |