| Blue Daze Design Limited | Information & communication | 2004 |
| Blue Moon Circus LLP | | 2022 |
| Blue Planet Society C.I.C. | Professional & scientific | 2022 |
| Bluesky (Dubarry) Ltd | Real estate | 2023 |
| Border News Limited | Wholesale & retail | 2008 |
| Box Clever.Homes Ltd | Administrative & support | 2023 |
| BP Supplies Ltd | Wholesale & retail | 2020 |
| Bradsons Aviation Services Ltd. | Administrative & support | 2013 |
| Braziers (Autos) Limited | Wholesale & retail | 1992 |
| Brazilian Kampers Ltd | Wholesale & retail | 2013 |
| Breakthrough Talk Ltd | Health & social care | 2017 |
| Brian Lang Management Limited | Information & communication | 1997 |
| Brighton Bouncy Castles Ltd | Arts & recreation | 2024 |
| Brighton Elite Decor Limited | Construction | 1996 |
| Brighton Gift Shop Limited | Wholesale & retail | 2022 |
| Brighton Water Shoes Ltd | Wholesale & retail | 2023 |
| Broadlight Limited | Information & communication | 2017 |
| Broadstone Trading Ltd | Real estate | 2015 |
| Brook 360 Holdings Ltd | Financial services | 2025 |
| Bryant Project Management Ltd | Real estate | 2018 |
| Bushen Property Limited | Real estate | 2017 |
| C W Trimming Limited | Wholesale & retail | 2014 |
| Camino Naturo Limited | Health & social care | 2025 |
| Carbon 12.011 (UK) Ltd | Wholesale & retail | 2024 |
| Carlsson Ltd | Information & communication | 2026 |
| Carreck Consultancy Ltd | Professional & scientific | 2018 |
| Carters Holiday Homes Ltd | Hospitality | 2022 |
| Casainvest Limited | Real estate | 2013 |
| Cbg:Together Ltd | Professional & scientific | 2025 |
| Ceecom Consult Ltd | Administrative & support | 2009 |
| Ceecom Geotech Ltd | Professional & scientific | 2023 |
| Central Electrical Solutions Ltd | Construction | 2013 |
| CES Fire & Electrical Limited | Construction | 2025 |
| Ceylon Escapes Ltd | Hospitality | 2024 |
| Chalet Nantes Ltd | Hospitality | 2020 |
| Chalk & Weald Ltd | Real estate | 2013 |
| Chandler and Reene Limited | Wholesale & retail | 2012 |
| Cherish Care for YOU and Your Home Limited | Health & social care | 2006 |
| Cherry Wren Ltd | Real estate | 2025 |
| Chez Joel Limited | Wholesale & retail | 2008 |
| Childrens Orthopaedics Ltd | Real estate | 2019 |
| Cindym Ltd | Administrative & support | 2025 |
| CJ Manufacturing Limited | Manufacturing | 2013 |
| CL Farriery Limited | Agriculture & fishing | 2018 |
| Classic Arcades Ltd | Manufacturing | 2013 |
| Clear Path Digital Ltd | Information & communication | 2025 |
| Climb the Ladder Limited | Real estate | 2017 |
| Clinic Eleven Aesthetics Ltd | Health & social care | 2022 |
| CLT Enviro-Law Ltd | Other services | 2008 |
| Cockeyed Film and Video Ltd | Information & communication | 2003 |
| Coles Automotive Holdings Limited | Wholesale & retail | 2022 |
| Coles Automotive Ltd | Wholesale & retail | 2013 |
| Coles Automotive Property Limited | Construction | 2022 |
| Collector Clash Limited | Wholesale & retail | 2025 |
| Company Health Services Limited | Health & social care | 2000 |
| Contemporary Garden Studios Ltd | Construction | 2020 |
| Core Structural Engineering Limited | Professional & scientific | 2023 |
| Corporate Administration Management Limited | Professional & scientific | 1998 |
| Cosmic (Sussex) Limited | Hospitality | 2020 |
| Countryman Improvements Limited | Construction | 1995 |
| Courage Works Ltd | Professional & scientific | 2025 |
| Courtwick Automotive Ltd | Professional & scientific | 2021 |
| Crazy Daizy Properties Ltd | Real estate | 2023 |
| CRG Racing Ltd | Arts & recreation | 2022 |
| Crompton Legal Ltd | Health & social care | 2024 |
| Crompton Property Ltd | Real estate | 2020 |
| Crowns Venues Ltd | Hospitality | 2020 |
| Cubic Storage Limited | Professional & scientific | 2020 |
| D & K Heasman Limited | Construction | 2007 |
| D C Coachworks (Henfield) Limited | Wholesale & retail | 2008 |
| D H Professional Services Ltd | Construction | 2013 |
| D J Flooring Limited | Wholesale & retail | 2005 |
| D S a Products Limited | Manufacturing | 1999 |
| D&G Holiday Lets Ltd | Real estate | 2021 |
| Daniel Steele Racing Ltd | Agriculture & fishing | 2024 |
| Darren Hedderman Consultancy Limited | Information & communication | 2020 |
| Datasmiths Solutions Limited | Information & communication | 2010 |
| DB Property Investments Limited | Transport & logistics | 2002 |
| DBC Community Greengrocers Limited | Wholesale & retail | 1999 |
| DC Trade Sales Limited | Wholesale & retail | 2016 |
| DE LA Street Ltd | Information & communication | 2020 |
| Dean Rush Designs Limited | | 2009 |
| Debbie Howells Limited | Arts & recreation | 2014 |
| DEM Fish Ltd | Hospitality | 2024 |
| Dent Magician Limited | Wholesale & retail | 1992 |
| Design by L&L Gardening Ltd | Professional & scientific | 2025 |
| Dextrous Productions Ltd | Information & communication | 2018 |
| DGA Plastering Services Ltd | Extraterritorial | 2014 |
| Direct Cable Supplies Ltd | Extraterritorial | 2010 |
| DJS Building Contractors Limited | Construction | 2004 |
| DKA ETC Limited | Administrative & support | 2012 |
| Donkeys Rule Ltd | Other services | 2010 |
| Donkeys Rule the World Ltd | Extraterritorial | 2017 |
| Doughboy U.K. Limited | Wholesale & retail | 2001 |
| Downlands Construction Limited | Construction | 2021 |
| Downsedge Mortgage Limited | Real estate | 2024 |
| DR MAC Clinic Ltd | Health & social care | 2025 |
| Drey Limited | Administrative & support | 2007 |
| Driven (Sussex) Limited | Transport & logistics | 2019 |
| DROP4DROP Limited | Administrative & support | 2006 |