| Deshee's Nest Limited | Administrative & support | 2025 |
| Design & Build Properties Ltd | Real estate | 2024 |
| Design Studio CC Limited | Professional & scientific | 2018 |
| Designed Storage & Handling Limited | Manufacturing | 1970 |
| Designibl Ltd | Information & communication | 2020 |
| Designs by KIM Limited | Professional & scientific | 2002 |
| Desire (Kiveton Park) Management Company Limited | Households | 2005 |
| Destiny (Kirkby View) Management Company Limited | Households | 2005 |
| Deteralert Limited | Information & communication | 2010 |
| Dev-Ex Consulting Limited | Information & communication | 2020 |
| Devbeat Software Ltd | Information & communication | 2024 |
| Devis Transport Ltd | Wholesale & retail | 2020 |
| Devolution AI Ltd | Professional & scientific | 2008 |
| Devolution Media Group Ltd | Information & communication | 2010 |
| Devolution Media Ltd | Information & communication | 2003 |
| Devon Choice Limited | Financial services | 2019 |
| Devonshire Place (Grays) Management Company Limited | Households | 2019 |
| Dewbloom Ltd | Wholesale & retail | 2025 |
| Dexgrange Limited | Construction | 2020 |
| DEY Mechanical Services Ltd | Construction | 2016 |
| DFC Contractors Ltd | Construction | 2026 |
| DFC Installations. Limited | Construction | 2021 |
| DG Aurelian Ltd | Transport & logistics | 2022 |
| DG Carpentry Limited | Manufacturing | 2025 |
| DG Futures Ltd | Financial services | 2024 |
| DG Professional Golf Services Limited | Wholesale & retail | 2019 |
| DH Carpenter & Joinery Ltd | Construction | 2025 |
| DH Construction Contractors Limited | Manufacturing | 2025 |
| Dharanaflow Limited | Real estate | 2024 |
| Dhenda Interrnational Ltd | Manufacturing | 2026 |
| Dhma Ltd | Transport & logistics | 2023 |
| DHR Trading Limited | Wholesale & retail | 2024 |
| DI Capri Pizza Ltd | Hospitality | 2018 |
| Diamond Lighting Ltd | Construction | 2014 |
| Diamond Shine HW Ltd | Other services | 2026 |
| Diamond Talent Ltd | Administrative & support | 2021 |
| Diamonds, Pearls and Crystals CIC | Administrative & support | 2026 |
| Diandri Ltd | Construction | 2014 |
| Diashub Ltd | Wholesale & retail | 2026 |
| Dickens Place (Totton) Management Company Limited | Households | 2010 |
| DID Construct Ltd | Construction | 2022 |
| Didi & Maya Ltd | Construction | 2019 |
| Diem Technical Consulting Limited | Information & communication | 2025 |
| Digi Gear Ltd | Information & communication | 2008 |
| Digibee Design Ltd | Manufacturing | 2016 |
| Digiflame Ltd | Professional & scientific | 2023 |
| Digisa Marketing Ltd | Professional & scientific | 2024 |
| Digisec Design Limited | Real estate | 2015 |
| Digital Distribution (GB.) Ltd. | Wholesale & retail | 2002 |
| Digital Health Partners UK Limited | Information & communication | 2026 |
| Digital Healthcare Limited | Information & communication | 1999 |
| Digital Iteration Consulting Ltd | Professional & scientific | 2019 |
| Digital Leadership Associates Ltd | Professional & scientific | 2016 |
| Digital Sourcing Group Ltd | Administrative & support | 2018 |
| Digital Stratagems Limited | Information & communication | 2022 |
| Digital Vision AV Limited | Information & communication | 2006 |
| Dignity Private Care Limited | Health & social care | 2025 |
| Dignum Limited | Professional & scientific | 2009 |
| Dine Smart Ltd | Wholesale & retail | 2019 |
| Dinky Doos & Dinky Donts Ltd | Extraterritorial | 2025 |
| Direct Umbrella Consultants Limited | Transport & logistics | 2019 |
| Direct Umbrella Ltd | Professional & scientific | 2017 |
| Dirty Dollar Drinks Ltd | Wholesale & retail | 2024 |
| Disciplai Ltd. | Professional & scientific | 2025 |
| Discourse Maestro Ltd | Wholesale & retail | 2020 |
| Disim Property Ltd | Real estate | 2025 |
| Ditto Film Services Ltd | Information & communication | 2015 |
| Diverse Asset Management Ltd | Real estate | 2017 |
| Diverse Print & Design Ltd | Manufacturing | 2009 |
| Divine Dance Classes Ltd | Education | 2024 |
| Divine Flava Ltd | Wholesale & retail | 2017 |
| Divinely Vintage Ltd | Wholesale & retail | 2010 |
| Diwis Creations CIC | Education | 2022 |
| DJ Matty F Events Ltd | Arts & recreation | 2025 |
| DJN Commercial Truck Services Ltd | Manufacturing | 2025 |
| Djoumessi Limited | Professional & scientific | 2018 |
| DJR Build Ltd | Construction | 2024 |
| DK Heating & Plumbing Services Ltd | Construction | 2021 |
| DL Waste Services Limited | Water & waste | 2022 |
| Dl&Lj Holdings Ltd | Real estate | 2020 |
| DLA Ignite Ltd | Extraterritorial | 2019 |
| DLG Plumbing & Heating Ltd | Construction | 2025 |
| DLN (ST Albans) Limited | Real estate | 2011 |
| DLS Distribution Ltd | Information & communication | 2019 |
| DM Enterprise Retail Limited | Wholesale & retail | 2021 |
| DMA Bright Life Support Ltd | Health & social care | 2020 |
| DMC Internal Limited | Construction | 2019 |
| DMD Health Care Ltd | Extraterritorial | 2022 |
| DMF Ventures Ltd | Professional & scientific | 2021 |
| Dmhc Associates Limited | Education | 2022 |
| DMX Trading Limited | Wholesale & retail | 2025 |
| DN and J Ltd | Construction | 2024 |
| Dobmatt Ltd | Construction | 2020 |
| Docsinnovent Limited | Manufacturing | 2009 |
| Doggy Playground Ltd | Other services | 2022 |
| Dogilo Limited | Information & communication | 2017 |
| Doherty Property Limited | Real estate | 2016 |
| Dolby Media Limited | Hospitality | 2024 |
| Dollin Building Services Ltd | Construction | 2026 |
| Domi Bathrooms Limited | Construction | 2017 |