| Pomus Margate Ltd | Wholesale & retail | 2023 |
| Popcorn Architecture Ltd | Professional & scientific | 2025 |
| Porpora Creatives Ltd | Professional & scientific | 2025 |
| Possingworth Park Estate (1990) Limited | Real estate | 1989 |
| Powells of Sussex Ltd | Real estate | 2016 |
| PP Assets Limited | Transport & logistics | 2019 |
| PPS Refurbishments Ltd | Real estate | 2021 |
| Pratt Digital Ltd | Professional & scientific | 2013 |
| Precision Cutting Ltd. | Construction | 1994 |
| Predipedia Ltd | Real estate | 2020 |
| Prepwell Ltd | Education | 2023 |
| Prestige Paintworks Ltd | Wholesale & retail | 2012 |
| Prime Accounting and Solutions Ltd | Professional & scientific | 2026 |
| Prime Software Development Limited | Information & communication | 2019 |
| Profps Ltd | Professional & scientific | 2019 |
| Property Renovations (Sussex) Limited | Construction | 2023 |
| Proplondon Ltd | Health & social care | 2011 |
| Prosperaworld Consulting Ltd | Professional & scientific | 2024 |
| Prosurv Home Inspections Ltd | Administrative & support | 2006 |
| Proud-Bailey Company Limited | Arts & recreation | 1961 |
| Providence Property Group Ltd | Real estate | 2022 |
| Prymak Holdings Limited | Real estate | 2009 |
| Prymak Referrals Limited | Professional & scientific | 2002 |
| Public Interest Planning Limited | Professional & scientific | 2019 |
| Pubs Advisory Service Ltd | Other services | 2012 |
| Punnetts Town Village Hall | Professional & scientific | 2004 |
| QLL4 Ltd | Financial services | 2025 |
| Quali-Teak Limited | Wholesale & retail | 2002 |
| Quality Outside Living Ltd | Administrative & support | 2014 |
| QUI Vive Limited | Financial services | 1973 |
| Quintana Ltd | Agriculture & fishing | 2010 |
| R H and L Limited | Administrative & support | 2025 |
| R J Holland (Properties) Limited | Real estate | 1988 |
| R Rogers Carpentry & Building LLP | | 2017 |
| R.N.P GAS Services and Engineering Ltd | Construction | 2022 |
| Radiant Facial Rejuvenation Limited | Other services | 2012 |
| Randall Management Limited | Professional & scientific | 2015 |
| Ransley Estates Ltd. | Real estate | 2012 |
| RB Logistics Services Ltd | Transport & logistics | 2026 |
| RB Marine Consultancy Ltd | Manufacturing | 2025 |
| RB Marine Ltd | Manufacturing | 2020 |
| RB Urban Estates Ltd | Real estate | 2024 |
| RBR Builders Limited | Manufacturing | 2016 |
| Read Shepley Limited | Financial services | 2003 |
| Readstru Limited | Professional & scientific | 2020 |
| Rebar Technology Ltd | Information & communication | 2025 |
| Records Asset Management Limited | Administrative & support | 2007 |
| Red and Green Marketing Limited | Extraterritorial | 2019 |
| Red Estates (UK) Limited | Real estate | 1999 |
| Red Ghyll Farming Ltd | Agriculture & fishing | 2019 |
| Red Paint 2001 Limited | Other services | 2001 |
| Red Paint Holdings Limited | Administrative & support | 1999 |
| Redline Venture Limited | Wholesale & retail | 2015 |
| Reed Plant Hire Ltd | Construction | 2004 |
| Renaissance Estates Limited | Real estate | 2019 |
| Renx Limited | Professional & scientific | 2013 |
| Restored | Health & social care | 2010 |
| Retail Connexions Ltd | Professional & scientific | 2022 |
| Retro Rebellion Ltd | Wholesale & retail | 2025 |
| Retro Reset Ltd | Education | 2025 |
| RETRO9 Limited | Wholesale & retail | 2023 |
| Return on Data Limited | Information & communication | 2014 |
| Revivesussex Ltd | Arts & recreation | 2024 |
| Rewind Group Ltd | Information & communication | 2020 |
| Riahippo LLP | | 2011 |
| Richard Allen Services Limited | Administrative & support | 2007 |
| Richardson Property Lawyers Limited | Professional & scientific | 2013 |
| Ricky's Ltd | Other services | 2022 |
| Rightfoot Adventures Limited | Administrative & support | 2011 |
| RLS Properties Limited | Real estate | 2004 |
| RLT Electrics Ltd | Construction | 2023 |
| Robert Bingham Yacht Surveys Limited | Extraterritorial | 2013 |
| Robert Cotterstock Fabrics Ltd | Professional & scientific | 2026 |
| Roche Electrical Limited | Construction | 2022 |
| Roger Peace Limited | Administrative & support | 2018 |
| Rolling Fields View Management Company Limited | Households | 2025 |
| Rooz Limited | Public administration | 2010 |
| Roselea Business Management Ltd | Administrative & support | 2020 |
| Rothschild Collection Limited | Administrative & support | 2000 |
| RS Risk Solutions Limited | Financial services | 2019 |
| RS Support Services Limited | Administrative & support | 2015 |
| Rsvpa Limited | Administrative & support | 2021 |
| Rudge Motorcycles Ltd | Manufacturing | 2017 |
| RUI XIN 2025 Ltd | Hospitality | 2025 |
| Rumlie Farming Ltd | Agriculture & fishing | 2023 |
| S & N Hicks Ltd | Wholesale & retail | 2011 |
| S & S Sussex Holdings Ltd | Real estate | 2025 |
| S Kemp & Sons (Builders) Ltd | Construction | 2003 |
| S&S Drainage Ltd | Construction | 2020 |
| S. & M. Building & Constructional Co. Limited | Real estate | 1973 |
| S4ENCRYPT Limited | Information & communication | 2019 |
| Sacrofence Ltd | Wholesale & retail | 2024 |
| SAM Construction Limited | Agriculture & fishing | 2002 |
| Sanctuary Farm Community Interest Company | Education | 2026 |
| Sandycross Wealth Management LLP | | 2009 |
| Sandycross Wealth Solutions Ltd | Financial services | 2009 |
| Sansom Paving Ltd | Construction | 2016 |
| Sanzman Solutions Ltd | Professional & scientific | 2011 |
| Sapphire Healthcare UK Ltd | Professional & scientific | 2003 |
| Sarm Limited | Real estate | 1981 |