| Sea-Faj Consults Limited | Administrative & support | 2025 |
| Seaburg Shipping and Logistics Ltd | Wholesale & retail | 2021 |
| Seafood Centre International Limited | Administrative & support | 1997 |
| Seatre Ltd | Real estate | 2018 |
| SEB Leparda Limited | Construction | 2026 |
| Sebs - Mart Ltd | Wholesale & retail | 2026 |
| Secret Place Records Ltd | Arts & recreation | 2007 |
| Secure Asset Assist Limited | Transport & logistics | 2024 |
| Secure Roofing and Building Maintenance Limited | Construction | 2024 |
| Secure Sure Ltd | Transport & logistics | 2021 |
| Securesend Ltd | Wholesale & retail | 2025 |
| Securespace Management Limited | Real estate | 2026 |
| Security Office Ltd | Administrative & support | 2020 |
| Security Guards London Limited | Administrative & support | 2023 |
| Security Links Ltd | Wholesale & retail | 2017 |
| SED Joinery Ltd | Construction | 2016 |
| Sedana Investments Limited | Financial services | 2021 |
| Seekers Limited | Information & communication | 2024 |
| Sehdev Investments Ltd | Real estate | 2025 |
| Sehgal Solutions Ltd | Hospitality | 2025 |
| Sehmi Properties Limited | Real estate | 2018 |
| SEJ & SEB Transport Ltd | Transport & logistics | 2016 |
| SEJ Assets Limited | Real estate | 2014 |
| SEJ Commercial Limited | Real estate | 2023 |
| SEJ Distribution Ltd | Wholesale & retail | 2008 |
| SEJ Estates Limited | Real estate | 2023 |
| SEJ Holdings Limited | Financial services | 2023 |
| SEJ Midlands Limited | Wholesale & retail | 2017 |
| SEJ Pharmaceutical Limited | Wholesale & retail | 2022 |
| Sekhon Builders Ltd | Construction | 2021 |
| Sekhon Building Solutions Ltd | Construction | 2024 |
| Sekhon Construction Limited | Construction | 2010 |
| Sekhon Estates Ltd | Real estate | 2026 |
| Sekhon Homes Ltd | Real estate | 2020 |
| Selam Haulage Ltd | Transport & logistics | 2018 |
| Selebrates UK Ltd | Information & communication | 2025 |
| Select Energy UK Ltd | Real estate | 2009 |
| Select Hire Limited | Administrative & support | 2025 |
| Select N Save Food & Wine Ltd | Wholesale & retail | 2013 |
| Self Sponsor Ltd | Information & communication | 2025 |
| Sellevo Ltd | Wholesale & retail | 2025 |
| Sellingbyus Ltd | Wholesale & retail | 2021 |
| Sellnexa Trading Ltd | Wholesale & retail | 2026 |
| Sellvora Commerce Ltd | Wholesale & retail | 2026 |
| Seltico Limited | Construction | 2017 |
| Selvams Homes Ltd | Real estate | 2025 |
| Selvasai Ltd | Hospitality | 2021 |
| Sempla Trading Ltd | Construction | 2026 |
| Sempla Transport Limited | Transport & logistics | 2026 |
| Sena Shine Decorators Ltd | Manufacturing | 2024 |
| Senalink Global Ltd | Wholesale & retail | 2025 |
| Sensitive Hearts Ltd | Education | 2026 |
| Seraph Beauty Ltd | Other services | 2024 |
| Serene Settings Ltd | Other services | 2025 |
| Serenity HS Limited | Health & social care | 2024 |
| Serverslot Ltd | Information & communication | 2026 |
| Service Assets Limited | Financial services | 2009 |
| Sethi Designers Ltd | Wholesale & retail | 2019 |
| Setsquare Limited | Construction | 2025 |
| Setup and Development Services Ltd | Administrative & support | 2010 |
| Seven Continents Removals & Storage Ltd | Transport & logistics | 2021 |
| Seven Day Scaffolding Limited | Construction | 2025 |
| Seven Seas Shipping Ltd | Extraterritorial | 2004 |
| Seven Star Construction Ltd | Construction | 2025 |
| Severus House (Hayes) RTM Company Limited | Households | 2025 |
| Sewak Johal Ltd | Construction | 2026 |
| Seylon Traders Limited | Transport & logistics | 2021 |
| SG Clinical Ltd | Professional & scientific | 2025 |
| SG Group Ltd | Hospitality | 2019 |
| SGM Construction Ltd | Construction | 2026 |
| SH & M Traders Ltd | Other services | 2020 |
| SH Accessories Limited | Wholesale & retail | 2025 |
| SH Fitting Ltd | Construction | 2025 |
| SH Roofing London Limited | Construction | 2022 |
| Shaayan Limited | Wholesale & retail | 2022 |
| Shack Empire Ltd | Hospitality | 2019 |
| Shafin & Co Ltd | Wholesale & retail | 2024 |
| Shagoon Jewellery Limited | Administrative & support | 2006 |
| Shagoon Properties Limited | Real estate | 2009 |
| Shah Brave Ltd | Wholesale & retail | 2022 |
| Shah Corporate Limited | Transport & logistics | 2021 |
| Shah Design & Build Ltd | Construction | 2012 |
| Shah Essentials Ltd | Wholesale & retail | 2018 |
| Shah Group Limited | Construction | 2023 |
| Shah JEE Dhaba Ltd | Hospitality | 2025 |
| Shah Kitchens & Bedrooms Ltd | Manufacturing | 2024 |
| Shah Property & Lettings Ltd | Real estate | 2023 |
| Shah Silverdale Ltd | Real estate | 2024 |
| Shah TBK Ltd | Wholesale & retail | 2020 |
| Shah Windows & Doors Ltd | Construction | 2022 |
| Shaheed Bhagat Singh Club Hayes Ltd | Arts & recreation | 2016 |
| Shaheen International UK Ltd | Other services | 2019 |
| Shahjahan Ltd | Wholesale & retail | 2025 |
| Shahnaz Hair & Beauty Ltd | Other services | 2017 |
| Shahzada Yousaf Ltd | Extraterritorial | 2022 |
| Shahzain Jewellers Limited | Manufacturing | 2015 |
| Shakan Properties Limited | Real estate | 2018 |
| Shakeel Developments Ltd | Construction | 2026 |
| Shaker Designs Ltd | Construction | 2018 |
| Shakes 4 London Ltd | Hospitality | 2023 |