| RTW Productions Ltd | Information & communication | 2022 |
| Ruben M. Trans Ltd | Transport & logistics | 2021 |
| Rubix Asset Ltd | Professional & scientific | 2015 |
| Ruby Fire Protection Ltd | Public administration | 2015 |
| Rubyleo Limited | Health & social care | 2023 |
| Ruffled Feather Productions Ltd | Information & communication | 2024 |
| Rufmat Organisation Ltd | Manufacturing | 2013 |
| Runako Health Care Ltd | Health & social care | 2021 |
| RVP Communications Limited | Information & communication | 2018 |
| Ryal 3 Ltd | Real estate | 2024 |
| Ryan Reynolds Renovations Ltd | Construction | 2022 |
| Rydal Mount (Amenity Land) Management Company Limited | Households | 1994 |
| Rydal Mount Flat Management Company Limited | Households | 1994 |
| Rylapay Ltd | Financial services | 2026 |
| S & F Transport Ltd | Transport & logistics | 2019 |
| S and G Accounts LLP | | 2007 |
| S and M OIL Ltd | Wholesale & retail | 2026 |
| S Boakye Services Ltd | Health & social care | 2025 |
| S D Futures Trading Limited | Financial services | 2021 |
| S D Land & Property Limited | Real estate | 2022 |
| S H Travel Representation Ltd | Administrative & support | 2023 |
| S Khan Productions Ltd | Administrative & support | 2023 |
| S Torka Properties Ltd | Real estate | 2026 |
| S&A Home Services Ltd | Administrative & support | 2025 |
| S&B Building Solutions Ltd | Construction | 2012 |
| S&I Construct Ltd | Construction | 2021 |
| S&O Property Enterprises Limited | Real estate | 2026 |
| S.A.B Couriers Ltd | Transport & logistics | 2007 |
| S.A.S. Systems Ltd. | Information & communication | 1995 |
| S.B. Bond Ltd | Real estate | 2018 |
| S.G.Williams Consulting Ltd | Professional & scientific | 2024 |
| S.J. Tachographs Ltd | Professional & scientific | 2019 |
| S.T Contracts Limited | Construction | 2009 |
| S.T Development Solutions Limited | Construction | 2020 |
| S.T Residential Limited | Real estate | 2020 |
| S3J Trading Limited | Information & communication | 2014 |
| SA Roofing & Leak Testing Limited | Construction | 2013 |
| SAC Consult Limited | Financial services | 2016 |
| Safari Logistics Ltd | Transport & logistics | 2017 |
| Safe Drylining Ltd | Construction | 2015 |
| Safeguard Fire Consultancy & Training Ltd | Professional & scientific | 2023 |
| SAI Interiors Ltd | Other services | 2012 |
| SAI Subha Limited | Information & communication | 2019 |
| SAK Property Managment Limited | Real estate | 2025 |
| Saka Solutions Ltd | Public administration | 2022 |
| Sakura Works Limited | Financial services | 2015 |
| Sala Property Investments Ltd | Real estate | 2024 |
| Saley Consultants Limited | Information & communication | 2007 |
| Salisbury Law Limited | Professional & scientific | 2018 |
| SAM Takhar Data Consulting Limited | Information & communication | 2025 |
| SAM Williams Limited | Arts & recreation | 2003 |
| Sama Motors Ltd | Wholesale & retail | 2024 |
| Samco Advisors Ltd | Professional & scientific | 2025 |
| Sammon Holdings Ltd | Real estate | 2023 |
| Sammon Seoighe Property Ltd | Real estate | 2025 |
| Samrah Limited | Wholesale & retail | 2023 |
| Samrush Ltd | Financial services | 2017 |
| Sanathana Samskriti Ltd | Other services | 2026 |
| Sancak 12 Barber Ltd | Other services | 2024 |
| Sanctuary Holdings Limited | Real estate | 2017 |
| Sandra Lewis Nutrition Ltd | Health & social care | 2025 |
| Sandrock Hospitality Ltd | Professional & scientific | 2019 |
| Sanjeevini Limited | Health & social care | 2014 |
| Sankofa Heritage UK Limited | Professional & scientific | 2025 |
| Sara & Elena Ltd | Transport & logistics | 2017 |
| Sara Prestige Group Ltd | Administrative & support | 2023 |
| Sargents Electrics Limited | Construction | 2019 |
| SAS & Partners Ltd | Professional & scientific | 2019 |
| SAS Response Limited | Construction | 2024 |
| SAS Technique Ltd | Health & social care | 2022 |
| Saslash Ltd | Other services | 2020 |
| Satyay Ltd | Professional & scientific | 2016 |
| SAU Trans Limited | Transport & logistics | 2020 |
| SBM Water UK Ltd | Wholesale & retail | 2017 |
| SC Therapy Ltd | Health & social care | 2022 |
| SCG Solutions Ltd | Manufacturing | 2024 |
| Schoppen Ltd | Construction | 2018 |
| Scimath Education Ltd | Education | 2020 |
| Sciurus Property Limited | Real estate | 2020 |
| Scott-English Plumbing Services Limited | Construction | 2021 |
| Scotts Recycling Limited | Water & waste | 2010 |
| Scrapix Ltd | Wholesale & retail | 2024 |
| SCS Recycling Limited | Wholesale & retail | 2022 |
| SCV Trans Ltd | Transport & logistics | 2016 |
| SDA Medical Services Limited | Health & social care | 2016 |
| SDR Digital Solutions Limited | Information & communication | 2018 |
| Seams in Fashion Ltd | Manufacturing | 2020 |
| Search Property Management Ltd | Real estate | 2019 |
| Sebflys Ltd | Information & communication | 2021 |
| Sebymar Ltd | Transport & logistics | 2018 |
| Securepoint Systems Ltd | Construction | 2025 |
| Seda Express Ltd | Education | 2015 |
| SEE DO Travel Ltd | Administrative & support | 2018 |
| Seeker Solutions Ltd | Administrative & support | 2023 |
| Seema Properties Limited | Real estate | 2025 |
| Seer Ventures Limited | Financial services | 2021 |
| Segis-Vie Limited | Professional & scientific | 2016 |
| Segregated Payments Limited | Information & communication | 2011 |
| Self Storage Concierge Limited | Transport & logistics | 2017 |
| Sella Supermarket Ltd | Wholesale & retail | 2024 |