| Emphateam Limited | Health & social care | 2025 |
| Enable Access Solutions LP | | 2010 |
| Enchant Aesthetics Doctor Ltd | Health & social care | 2022 |
| Encore Auto Sales Ltd | Wholesale & retail | 2025 |
| END2END Marketing Ltd | Professional & scientific | 2021 |
| Englaza Services Ltd | Administrative & support | 2026 |
| Enid’S Care Angels Ltd | Health & social care | 2022 |
| Enki Construction Ltd | Construction | 2026 |
| Enserve Global Ltd | Wholesale & retail | 2023 |
| Entrepreneurial Skills Academy Ltd | Professional & scientific | 2007 |
| Enyi Estates Ltd | Real estate | 2024 |
| EON Associates Ltd | Professional & scientific | 2025 |
| Ephathas Kids Ltd | Wholesale & retail | 2026 |
| EPP Properties Ltd | Real estate | 2021 |
| EQ K9 Ltd. | Agriculture & fishing | 2023 |
| ERA Engineers Ltd | Construction | 2020 |
| ESA Plumbing & Heating Limited | Construction | 2024 |
| ESH Plumbing & Heating Ltd | Construction | 2019 |
| ESQ Coffee Kettering Limited | Hospitality | 2025 |
| ESQ Crowthorne Limited | Hospitality | 2024 |
| ESQ Kettering Limited | Hospitality | 2026 |
| ESQ ST Neots Coffee Shop Limited | Hospitality | 2017 |
| ESQ Sudbury Limited | Hospitality | 2023 |
| Esquires Coffee Brackley Ltd | Wholesale & retail | 2022 |
| Esquires Coffee Corby Limited | Hospitality | 2022 |
| Esquires Coffee Essex Limited | Hospitality | 2022 |
| Esquires Coffee Melton Mowbray Limited | Hospitality | 2022 |
| Essence Wellbeing Service Limited | Health & social care | 2018 |
| Essendon Golf Club Limited | Arts & recreation | 2025 |
| Essendon Properties Limited | Real estate | 2005 |
| Essendon Properties NO. 2 Limited | Construction | 2005 |
| Essex Radiolgy Limited | Health & social care | 2024 |
| Esthetic Green Star Handy Services Ltd | Other services | 2019 |
| Esuoh Holdings Ltd | Real estate | 2021 |
| Etechtric Limited | Construction | 2025 |
| Eternal Communications Ltd | Wholesale & retail | 2010 |
| Eton Heights (Management) Limited | Households | 2009 |
| Eureka Coffee Ltd | Wholesale & retail | 2019 |
| Eurexploit Ltd | Information & communication | 2007 |
| Eurisco Ltd | Other services | 2005 |
| Euro Arabian Limited | Wholesale & retail | 2013 |
| Euro Gardens Limited | Administrative & support | 2026 |
| Euro Lanka Suppliers Limited | Wholesale & retail | 2024 |
| European Eagle Limited | Administrative & support | 2024 |
| European Motors Ltd | Wholesale & retail | 2025 |
| Europlants (UK) Limited | Administrative & support | 1990 |
| Evan B. Mechanical Limited | Professional & scientific | 2015 |
| Eveam Limited | Professional & scientific | 2024 |
| Eventfull Catering Limited | Hospitality | 2020 |
| Everfaithful Limited | Public administration | 2022 |
| Evergreen Garden Solutions Ltd | Administrative & support | 2026 |
| Evergreen Marketing Limited | Information & communication | 2022 |
| Eversleigh Investment and Property Company Limited | Construction | 1956 |
| Eversley Park Limited | Households | 1995 |
| Everydayy Solutions Ltd | Wholesale & retail | 2025 |
| Evolution of Gardening Ltd | Administrative & support | 2025 |
| Evolve Financial Consulting Ltd | Professional & scientific | 2024 |
| Evolve Skah Ltd | Wholesale & retail | 2025 |
| EWI Specialist Ltd | Construction | 2015 |
| Excalibur Global Technology Ltd | Information & communication | 2019 |
| Excel Catering Services Limited | Hospitality | 2013 |
| Excel Real Estate Limited | Professional & scientific | 2008 |
| Excellence Academy for Education and Training Ltd | Education | 2019 |
| Excellent Ventures Ltd | Hospitality | 2026 |
| Exclusive Care Limited | Health & social care | 2011 |
| Execusafe Ltd | Professional & scientific | 2011 |
| Exeliad Limited | Wholesale & retail | 2023 |
| Exemplas Limited | Administrative & support | 2000 |
| Exit Trade Ltd | Transport & logistics | 2024 |
| Exodus Social Care Limited | Health & social care | 2020 |
| Express Grocery Ltd | Wholesale & retail | 2025 |
| Eyecue Solutions Limited | Information & communication | 2009 |
| Ezmic Care Limited | Administrative & support | 2023 |
| F & F Contractors Limited | Construction | 2025 |
| F J Freeman Consulting Services Ltd | Professional & scientific | 2025 |
| F&E Driving Ltd | Transport & logistics | 2017 |
| F. Place Management Limited | Administrative & support | 1984 |
| F2A2E Limited | Wholesale & retail | 2021 |
| Fabodek Ltd | Health & social care | 2024 |
| Fairfax Plumbing and Heating Supplies Limited | Construction | 1995 |
| Fairlife Foundation Limited | Other services | 2012 |
| Fairlife Limited | Administrative & support | 2014 |
| Fairoam Ltd | Information & communication | 2025 |
| Fairway Construction Home Counties Ltd | Construction | 2026 |
| Fairway Construction Services Ltd | Administrative & support | 2026 |
| Fairy Folds Ltd | Other services | 2025 |
| Faith & Grace Hair and Beauty Limited | Other services | 2015 |
| Faith Preachers Ministries UK Ltd | Other services | 2025 |
| FAITHBASE9 Global Company Limited | Construction | 2020 |
| Faizcom Limited | Real estate | 2019 |
| Falko Regional Aircraft Limited | Administrative & support | 2011 |
| Fandsons Limited | Transport & logistics | 2025 |
| Fan`S WIN Ltd | Wholesale & retail | 2009 |
| Faringford Close Ltd | Real estate | 2017 |
| Farnridge Limited | Professional & scientific | 1984 |
| Farringford Ltd | Construction | 2024 |
| Fast Draft Limited | Wholesale & retail | 2020 |
| Fast Parcel Courier Ltd | Transport & logistics | 2023 |
| Favorite Chicken Ltd | Hospitality | 2018 |
| Fcity Ltd | Wholesale & retail | 2025 |