| Digisa Ltd | Wholesale & retail | 2025 |
| Digit Computers Ltd | Other services | 2015 |
| Digital Innovations LAB Ltd | Wholesale & retail | 2017 |
| Digital Lifecycle Management Limited | Professional & scientific | 2024 |
| Digital SR Limited | Information & communication | 2019 |
| Digital Technologies Limited | Hospitality | 2023 |
| Digitixerz Ltd | Wholesale & retail | 2025 |
| Dignity Lane Care Ltd | Health & social care | 2024 |
| Digpacks Ltd | Information & communication | 2019 |
| Dijim Group Limited | Information & communication | 2025 |
| Dimon Beauty Limited | Other services | 2025 |
| DIN Logistics Ltd | Wholesale & retail | 2019 |
| Direct Plumbing & Heating Services Limited | Construction | 2017 |
| Direct Sun Ltd | Extraterritorial | 2023 |
| Disruptive Icon Ltd | Administrative & support | 2025 |
| Distaff Properties Limited | Households | 1981 |
| Diversify London Limited | Wholesale & retail | 2022 |
| Divinestyles Ltd. | Wholesale & retail | 2020 |
| Dixon Waste Solutions Ltd | Water & waste | 2025 |
| DIY DNA Ltd | Wholesale & retail | 2017 |
| DJ Belfast Limited | Financial services | 2021 |
| DJ Glems Services Limited | Financial services | 2021 |
| DJP Assessors Limited | Other services | 2014 |
| DK Freshouse Ltd | Construction | 2015 |
| Dkar Limited | Wholesale & retail | 2023 |
| DL Autohaus Ltd | Wholesale & retail | 2022 |
| Dl-B Maintenace Limited | Construction | 2024 |
| DLB Corporation Ltd | Wholesale & retail | 2015 |
| DLL Greenwich Limited | Financial services | 2020 |
| DM Engineering Services Ltd | Manufacturing | 2021 |
| DMB 777 Limited | Hospitality | 2023 |
| DMC Digital Design Ltd | Professional & scientific | 2017 |
| DMC Investments Limited | Financial services | 2020 |
| DMS (UK) Ltd | Water & waste | 2012 |
| DNA Air Conditioning Limited | Wholesale & retail | 2012 |
| Dnbk Capital Holdings Ltd | Financial services | 2026 |
| DNV Haulage Ltd | Transport & logistics | 2026 |
| Do&Mi Limited | Real estate | 2025 |
| Doll Hairs Ltd | Administrative & support | 2024 |
| Dols - Divine Mercy Limited | Health & social care | 2023 |
| Domain Protection Services Limited | Information & communication | 2014 |
| Domestico Ltd | Administrative & support | 2015 |
| DON Luis Limited | Health & social care | 2022 |
| DON Pronto Ltd | Wholesale & retail | 2018 |
| DON TA Ltd | Transport & logistics | 2024 |
| DONATAS01 Transport Ltd | Transport & logistics | 2016 |
| Donex Couriers Ltd | Transport & logistics | 2026 |
| Donner & More Ltd | Hospitality | 2023 |
| Dopplle Limited | Professional & scientific | 2020 |
| Dora Service Limited | Health & social care | 2019 |
| Dotvanix Ltd | Information & communication | 2026 |
| Doughnut Developments Ltd | Information & communication | 2016 |
| Dove Group Limited | Wholesale & retail | 1928 |
| Dower Design Limited | Construction | 2011 |
| Dower Group Limited | Construction | 2009 |
| Dower Investments Limited | Construction | 2024 |
| Down the Woods C.I.C. | Education | 2016 |
| Downfield Road Limited | Real estate | 2025 |
| Downhaul Limited | Information & communication | 2015 |
| Downhurst Healthcare Limited | Health & social care | 2021 |
| Downing Court Management Co. Limited | Households | 1988 |
| Dozen Services Ltd | Wholesale & retail | 2022 |
| DP Aero Support Limited | Manufacturing | 2014 |
| DPL Building Ltd | Construction | 2026 |
| DR Alexa Roxborough Limited | Health & social care | 2024 |
| DR Matilda a. Ralph Limited | Professional & scientific | 2020 |
| Dragon Transport Limited | Transport & logistics | 2018 |
| Drama Llama AI Ltd | Information & communication | 2025 |
| Draper Mannan Ltd | Education | 2025 |
| Drashtikon Ltd | Real estate | 2021 |
| Drcr Limited | Professional & scientific | 2018 |
| Dream Abroad Educational Consultants Ltd | Education | 2021 |
| Dream Draw Competition Ltd | Arts & recreation | 2025 |
| Dreamclean Domestic Services Limited | Professional & scientific | 2020 |
| Dreamskin Health Limited | Manufacturing | 2004 |
| Drinkmore Stud Limited | Agriculture & fishing | 2024 |
| DRP Construction Ltd | Construction | 2026 |
| DRS Consultancy Ltd | Information & communication | 2022 |
| Dryline Dynamics Ltd | Construction | 2025 |
| DS Fit Ltd | Education | 2023 |
| Dshellard Ltd | Administrative & support | 2023 |
| Dsjp London Ltd | Wholesale & retail | 2023 |
| DSR Workspace Ltd | Construction | 2018 |
| DSV Building Services Consultancy Ltd | Professional & scientific | 2018 |
| DTM Flooring Limited | Wholesale & retail | 2021 |
| Duhok Barber Ltd | Other services | 2011 |
| Duncan SA Consultancy Limited | Information & communication | 2011 |
| DUO7 Vending Ltd | Wholesale & retail | 2026 |
| Dutt Designs Ltd | Construction | 2020 |
| DVD Transport Ltd | Transport & logistics | 2018 |
| DVL Recruitment Limited | Administrative & support | 2012 |
| Dykegrove Limited | Information & communication | 1982 |
| Dynamic & Deals Limited | Wholesale & retail | 2025 |
| Dynamical Systems Research Limited | Professional & scientific | 1993 |
| Dynamo Brickwork Ltd | Construction | 2017 |
| DYT Enterprise Ltd | Information & communication | 2025 |
| E C & B Limited | Real estate | 1995 |
| E C Bicester Limited | Hospitality | 2023 |
| E C Kettering Limited | Hospitality | 2023 |
| E C Luton Limited | Hospitality | 2021 |