| SEH Roofing Services Limited | Construction | 2012 |
| Select Event Solutions Limited | Administrative & support | 2014 |
| Sellers Investments Limited | Professional & scientific | 2016 |
| Sellers Investments Property Limited | Real estate | 2024 |
| Sensible Stays Ltd | Real estate | 2023 |
| Serenity Pools Ltd | Professional & scientific | 2015 |
| Seymours Estate Agents (Haslemere) Limited | Real estate | 2017 |
| SGL Forestry Limited | Agriculture & fishing | 2008 |
| Shahanaz Limited | Professional & scientific | 1998 |
| Sharpedge Associates Ltd | Professional & scientific | 2015 |
| Sharper Utility Mapping Limited | Administrative & support | 2018 |
| Shaun Moore Contracting Ltd | Information & communication | 2022 |
| Shepherds Field Management Company Limited | Households | 2006 |
| Shield Properties NE Ltd | Real estate | 2018 |
| Shottermill Limited | Financial services | 2021 |
| Shottermill Park Residents Limited | Households | 1999 |
| Shrive Holdings Ltd | Households | 2025 |
| Sians Studio Ltd | Professional & scientific | 2020 |
| Sickle Mill Court Limited | Real estate | 2014 |
| Sickle Mill Court RTM Company Limited | Real estate | 2012 |
| Sightline Media Ltd | Information & communication | 2012 |
| Sightline TV Limited | Information & communication | 2003 |
| Silk Trader Ltd | Hospitality | 2024 |
| Silver FOX Design & Build Limited | Professional & scientific | 2014 |
| Silverblue Tours Ltd | Administrative & support | 2006 |
| Simon Manuel Property Services Limited | Construction | 2007 |
| Sirin Consulting Limited | Professional & scientific | 2024 |
| SIX Mile Lake Property Ltd | Real estate | 2023 |
| SJ Creative Partners Ltd | Administrative & support | 2026 |
| SJC Accountancy Ltd | Professional & scientific | 2019 |
| Skeon Ltd | Wholesale & retail | 2025 |
| Skylark Point Properties Limited | Real estate | 2021 |
| Slade Court Developments Limited | Real estate | 2005 |
| Sleeve Magazine Ltd | Information & communication | 2026 |
| SLS Foods Limited | Hospitality | 2014 |
| Smart Associates Limited | Information & communication | 2003 |
| Smartson & Co Limited | Real estate | 2016 |
| Smash Creative Limited | Information & communication | 2008 |
| Smudge Cleaning Ltd | Administrative & support | 2022 |
| SN Sailing Limited | Arts & recreation | 2016 |
| Snowvale (Pevensey) Limited | Real estate | 2015 |
| Snowvale Developments Limited | Construction | 2014 |
| SO3 Projects (UK) Limited | Information & communication | 2011 |
| Solarix Ventures Ltd | Information & communication | 2021 |
| Solve Learning Ltd | Information & communication | 2015 |
| Sophie Wells Interiors Limited | Professional & scientific | 2007 |
| Sorensen Fenwick Smith Limited Partnership | | 2014 |
| Soulquestdestiny Ltd. | Administrative & support | 2020 |
| South Downs Homes (Liphook) Limited | Construction | 2025 |
| South Downs Homes Limited | Construction | 2025 |
| South Downs Ice Cream Ltd | Manufacturing | 2021 |
| South Downs Living Limited | Real estate | 2025 |
| South Eastern Projects Management Company Ltd | Manufacturing | 2007 |
| South London Shutters Ltd | Manufacturing | 2018 |
| South Mundham Farm Management Company Limited | Households | 2022 |
| South Park Farm Co Ltd | Agriculture & fishing | 2025 |
| Southern Counties Electrical Ltd | Construction | 2021 |
| Southern Counties Installations Ltd | Manufacturing | 2020 |
| Sparc Retail Ltd | Manufacturing | 2022 |
| Spartent Global Solutions Limited | Administrative & support | 2011 |
| Spencer Bonnett Limited | Real estate | 1982 |
| SPH Qualitech Ltd | Professional & scientific | 1995 |
| Spin Quantum Tech Ltd | Information & communication | 2022 |
| Spinar Limited | Administrative & support | 2013 |
| Spinney Residents' Association Limited | Households | 1990 |
| Spiral Travel Services Ltd | Other services | 2019 |
| Spitfire Capital Limited | Professional & scientific | 2025 |
| Spondoo Audit Limited | Professional & scientific | 2025 |
| Spondoo Umbrella IR35 Limited | Professional & scientific | 2020 |
| Sprouting Tiger Ltd | Wholesale & retail | 2019 |
| Spruce Fencing Complete Garden Services Ltd | Administrative & support | 2018 |
| Squircle Studio Ltd | Administrative & support | 2012 |
| Squirrel Financial Planning Ltd | Professional & scientific | 2025 |
| Sslam Limited | Real estate | 2019 |
| ST Mary's Abbey Management Company Limited | Real estate | 2012 |
| ST Storage Limited | Transport & logistics | 2015 |
| Staines Productions Limited | Information & communication | 2021 |
| Stand Sure Fitness & Martial Arts Ltd | Arts & recreation | 2023 |
| Stanningley Freehold Limited | Households | 2022 |
| Star Taxi Online Ltd | Transport & logistics | 2022 |
| Starboard Partners Ltd | Professional & scientific | 2025 |
| Stargazer Investments Limited | Professional & scientific | 2005 |
| Stelling Capital 2 Limited | Financial services | 2017 |
| Stelling Events Limited | Financial services | 2017 |
| Stelling Investments Limited | Administrative & support | 2008 |
| Stephen Rothwell Ltd | Information & communication | 2025 |
| Stetdomus Management Ltd | Construction | 2022 |
| Stoatley Rise Residents Association Limited (the) | Households | 1970 |
| Stobart Consulting Ltd | Information & communication | 2018 |
| Stocktanks UK Ltd | Wholesale & retail | 2021 |
| Stopham Plotters Association (Spa) CIC | Other services | 2017 |
| Storage & Services Limited | Real estate | 2015 |
| Storms of Eden Ltd | Wholesale & retail | 2025 |
| Straight Talking Speech and Language Therapy Ltd | Health & social care | 2022 |
| Stratxl Limited | Professional & scientific | 2010 |
| Streetnation Franchise Ltd | Administrative & support | 2023 |
| Streetnation Haslemere Ltd | Arts & recreation | 2023 |
| Structured Data Systems Limited | Information & communication | 2019 |
| Stryder Tech Ltd | Information & communication | 2024 |
| Stuart Harvey Showjumpers Limited | Other services | 2013 |