| DR Laura EID Ltd | Health & social care | 2025 |
| DR Mahdi Alosert Ltd | Health & social care | 2021 |
| DR Maxx Nutrition Ltd | Wholesale & retail | 2024 |
| DR Nabiah Aesthetics Limited | Health & social care | 2022 |
| DR NK Holdings Limited | Health & social care | 2025 |
| DR Noori Ltd | Health & social care | 2023 |
| DR Pamela Hamilton Ltd | Health & social care | 2023 |
| DR Peng Health Ltd | Administrative & support | 2017 |
| DR Rachel M Limbrey Limited | Health & social care | 2017 |
| DR RIA Investments Limited | Real estate | 2023 |
| DR S Chauhan Limited | Health & social care | 2023 |
| DR S Cleator Limited | Health & social care | 2020 |
| DR S S MED Ltd | Health & social care | 2025 |
| DR Skin Surgery Ltd | Health & social care | 2022 |
| DR Sparkle Cleaning Ltd | Administrative & support | 2026 |
| DR UK Investment Limited | Real estate | 2019 |
| DR UK Management Ltd | Real estate | 2020 |
| DR V & K Aesthetics Ltd | Health & social care | 2025 |
| DR W E Fickling Ltd | Health & social care | 2010 |
| Dragon Build Ltd | Construction | 2018 |
| Dragon Song Healing Ltd | Other services | 2018 |
| Dragon Warrior HQ Ltd | Other services | 2020 |
| Dragonstack UK Limited | Professional & scientific | 2014 |
| Dragos Contractors Ltd | Construction | 2013 |
| Dragos Drylining Limited | Construction | 2026 |
| Drake International Limited | Administrative & support | 1974 |
| Drake International Systems Limited | Administrative & support | 1968 |
| Drake Personnel Limited | Administrative & support | 1964 |
| Drama Shelve Limited | Arts & recreation | 2018 |
| Dramatic Events Limited | Administrative & support | 2012 |
| Draxall Ltd | Construction | 2024 |
| Draycott Avenue Management Company Limited | Households | 1996 |
| Draycott Guest House Ltd | Hospitality | 2019 |
| Draysen Limited | Professional & scientific | 2007 |
| Draytech Ltd | Administrative & support | 2012 |
| DRB Property Investments Ltd | Financial services | 2019 |
| Drbhavin Ltd | Health & social care | 2024 |
| DRD Wholesale Ltd | Wholesale & retail | 2024 |
| Dream & Dusk Ltd | Other services | 2022 |
| Dream Broker Ltd | Information & communication | 2023 |
| Dream Couriers Limited | Transport & logistics | 2020 |
| Dream Homes Investments Ltd | Information & communication | 2019 |
| Dream Korea Limited | Hospitality | 2022 |
| Dream Origin Ltd | Wholesale & retail | 2025 |
| Dream Scuba Yachting Ltd | Administrative & support | 2023 |
| Dream Sea Yachting Ltd | Extraterritorial | 2024 |
| Dreamraft Limited | Information & communication | 2015 |
| Dreamride Limited | Transport & logistics | 2024 |
| Dreams Asset Solutions Limited | Real estate | 2025 |
| Dreams by Design Limited | Professional & scientific | 2010 |
| Dreams Care Homes (Ynysddu) Limited | Health & social care | 2016 |
| Dreams Estates Limited | Real estate | 2022 |
| Dreamscape Consulting Limited | Other services | 2025 |
| DREAMSHOP14 Limited | Wholesale & retail | 2024 |
| Dreamwave Arts CIC | Information & communication | 2022 |
| Dreamweaver Films Ltd | Information & communication | 2026 |
| Dreamy Flutters Ltd | Manufacturing | 2022 |
| Dreamz Home Ltd | Administrative & support | 2024 |
| Drew Pearson International (Europe) Ltd | Other services | 2004 |
| Drijen Designs Limited | Information & communication | 2009 |
| Drink Purpose Ltd | Professional & scientific | 2025 |
| Drinks & Snacks Xpress Ltd | Wholesale & retail | 2013 |
| Drinks 2 Deliver (London) Limited | Wholesale & retail | 2020 |
| Drinks on Time . Co. UK. Limited | Wholesale & retail | 2012 |
| Drinkswala Ltd | Other services | 2023 |
| Drip & DRY Direct Ltd | Administrative & support | 2021 |
| Dripnsource Limited | Wholesale & retail | 2023 |
| Drippingberry Official Ltd | Wholesale & retail | 2024 |
| Drive Easy Driving School Ltd | Education | 2025 |
| Drive Electric Cars Ltd | Wholesale & retail | 2026 |
| Drive Home Properties Ltd | Real estate | 2023 |
| Drive Resource Studio Limited | Information & communication | 2024 |
| Drive the Best Ltd | Wholesale & retail | 2015 |
| Drive to Success Ltd | Other services | 2011 |
| Driven Ideas Ltd | Financial services | 2024 |
| Driver the Film Ltd | Information & communication | 2023 |
| Drivers Club Limited | Wholesale & retail | 2020 |
| Drivetime Cars Ltd | Wholesale & retail | 2010 |
| Driving School Wali Ltd | Education | 2026 |
| Driving School Walli Ltd | Education | 2024 |
| DRJ Medical Ltd | Health & social care | 2010 |
| DRK Jewellery Ltd | Manufacturing | 2024 |
| DRM Trans Ltd | Transport & logistics | 2024 |
| Drmp Consultancy Limited | Administrative & support | 2012 |
| Dromo Kitchen Ltd | Hospitality | 2026 |
| Drone Alps Ltd | Information & communication | 2015 |
| Dronexclean Ltd | Administrative & support | 2025 |
| Drop N Go Dispatch Ltd | Transport & logistics | 2017 |
| Dropcart Ltd | Wholesale & retail | 2018 |
| Droplet Pure UK Ltd | Professional & scientific | 2025 |
| Droplets Drinks Limited | Manufacturing | 2019 |
| Droppad Limited | Professional & scientific | 2017 |
| Dros & Sons Ltd | Construction | 2026 |
| DRP Enterprises Limited | Administrative & support | 2015 |
| Drug Comparison Ltd | Professional & scientific | 2012 |
| Drugsrus Limited | Wholesale & retail | 2003 |
| Druv Solutions Ltd | Administrative & support | 2017 |
| Drvyas Ltd | Wholesale & retail | 2026 |
| DRY Carpet Cleaner Limited | Administrative & support | 2024 |
| DRY Property - Damp & Mould Specialists Ltd | Professional & scientific | 2026 |