| SAM Finds Ltd | Wholesale & retail | 2026 |
| SAM Lisher Limited | Information & communication | 2017 |
| SAM Million Home Improvement Ltd | Real estate | 2019 |
| SAM National Properties Group Ltd | Real estate | 2016 |
| SAM Properties (Herts) Limited | Real estate | 2018 |
| SAM Sailing Ltd | Transport & logistics | 2022 |
| SAM TK Limited | Real estate | 2022 |
| Sam&Ash Limited | Hospitality | 2024 |
| Sam&Sang LLP | | 2021 |
| Sam's Food & Drinks Ltd | Hospitality | 2024 |
| SAM.66 Limited | Professional & scientific | 2015 |
| Samaca Archaeological Research Project Ltd | Professional & scientific | 2023 |
| Samantha Collier Orthodontics Ltd | Health & social care | 2024 |
| Samanthi Ltd | Health & social care | 2016 |
| Samanvika Limited | Hospitality | 2025 |
| Samara & Co Limited | Professional & scientific | 2012 |
| Samara Cuisine Ltd | Hospitality | 2002 |
| Samarpan Jewel Ltd | Construction | 2024 |
| Samart Solutions Ltd | Professional & scientific | 2013 |
| Samatra Property Services Limited | Real estate | 2024 |
| Samba Investments Limited | Real estate | 2018 |
| Sambhav Health Ltd | Professional & scientific | 2020 |
| Same Old Game Ltd | Construction | 2026 |
| Sameer (Europe) Limited | Administrative & support | 2005 |
| Sameer Enterprises International Ltd | Administrative & support | 2024 |
| Sami Bikes Ltd | Wholesale & retail | 2022 |
| Samia Housing Limited | Households | 2022 |
| Samidha & Company Ltd | Wholesale & retail | 2025 |
| Samir Ghodasara Limited | Health & social care | 2020 |
| Sammuelconsulting Ltd | Transport & logistics | 2022 |
| Samnxire Ltd | Information & communication | 2023 |
| Samoill Construction Ltd | Construction | 2019 |
| Samp Enterprise Limited | Wholesale & retail | 2020 |
| Sampada Consulting Limited | Professional & scientific | 2013 |
| Sampark Professionals CIC | Administrative & support | 2023 |
| Sampgold Ltd | Wholesale & retail | 2011 |
| Sampradaaya Music Ltd | Education | 2020 |
| Samraat IT Limited | Information & communication | 2019 |
| Samrat Indian Cuisine (Ealing) Limited | Hospitality | 2007 |
| Sams Mechanic Ltd | Wholesale & retail | 2018 |
| Samsara Advisory Ltd | Professional & scientific | 2026 |
| Samuda Partners Ltd | Other services | 2025 |
| Samuel Brickwork Ltd | Construction | 2022 |
| Samuel Nistor Ltd | Construction | 2020 |
| Samuel Plimsol House Ltd | Real estate | 2025 |
| Samuel Transport Limited | Transport & logistics | 2012 |
| Samurai Computers (U.K.) Limited | | 1991 |
| Samvit Services Ltd | Professional & scientific | 2016 |
| Samy Construction Limited | Construction | 2018 |
| Samy Fresh Food Ltd | Hospitality | 2026 |
| Samy-Express International Ltd | Transport & logistics | 2025 |
| Samyal Investments Limited | Real estate | 1962 |
| Samzaz Limited | Real estate | 2020 |
| Samzi Ltd | Health & social care | 2019 |
| SAN Auto Parts Ltd | Wholesale & retail | 2018 |
| SAN Homes Ltd | Real estate | 2017 |
| SAN Pearls Limited | Health & social care | 2026 |
| Sana (Reedham) Limited | Construction | 2014 |
| Sana Corp Ltd | Information & communication | 2018 |
| Sanam Investments Ltd | Real estate | 2024 |
| Sanam Jewellers Ltd | Wholesale & retail | 2016 |
| Sanam Limited | Wholesale & retail | 2025 |
| Sanaryan Lettings Limited | Real estate | 2024 |
| Sancroft Community Care Limited | Health & social care | 2017 |
| Sand & Stone Developments Limited | Real estate | 2013 |
| Sand Investments LDN Ltd | Real estate | 2020 |
| Sandea Freight Services Limited | Wholesale & retail | 2018 |
| Sandea Logistics Ltd | Transport & logistics | 2018 |
| Sandea Trading Limited | Wholesale & retail | 2025 |
| Sandea Wholesale Limited | Wholesale & retail | 2019 |
| Sander Pharma Limited | Wholesale & retail | 2018 |
| Sanders Property Partners Ltd | Real estate | 2014 |
| Sandlewood Films Limited | Information & communication | 2021 |
| Sandor Films Ltd | Information & communication | 2018 |
| Sandown Hill Ltd | Hospitality | 2019 |
| Sandpop Limited | Health & social care | 2015 |
| Sandringham Accountants Ltd | Professional & scientific | 2020 |
| Sandringham Estates Ltd | Real estate | 1997 |
| Sandringham Residents Company Limited | Professional & scientific | 2005 |
| Sandstone Training Limited | Professional & scientific | 2014 |
| Sandy Software Limited | Other services | 2018 |
| Sandycombe Development Limited | Construction | 2018 |
| Sandylight Limited | Wholesale & retail | 1986 |
| Saneco Limited | Wholesale & retail | 2020 |
| Sanela Yachting Ltd | Administrative & support | 2024 |
| Sang Homes Limited | Real estate | 2017 |
| Sang Marble Ltd | Other services | 2011 |
| Sangar Trading Limited | Other services | 2012 |
| Sangel Enterprise Limited | Hospitality | 2025 |
| Sangha Property Investments Ltd | Real estate | 2019 |
| Sangnil Investments Ltd | Information & communication | 2009 |
| Sani Consultancy Limited | Real estate | 2025 |
| Saniah Properties Limited | Administrative & support | 2026 |
| Sanidh Trading Co Ltd | Wholesale & retail | 2026 |
| Sanj Electrical Technology Ltd | Construction | 2025 |
| Sanjog Cart Ltd | Wholesale & retail | 2026 |
| Sanjona Ltd | Real estate | 2015 |
| Sankalp Pharma Services Limited | Professional & scientific | 2025 |
| Sankalp Product Limited | Wholesale & retail | 2025 |
| Sanmay Limited | Professional & scientific | 2017 |