| Yorkshire Textiles Limited | Professional & scientific | 2014 |
| Yorkshire Tool Supplies Limited | Wholesale & retail | 2026 |
| Yorkshire Vehicle Solutions Harrogate Ltd | Wholesale & retail | 2019 |
| Yorkshire Verandas Ltd | Construction | 2020 |
| Yorkshire Vitality Ltd | Health & social care | 2023 |
| Yorkshire Warrior Challenge Ltd | Arts & recreation | 2012 |
| Yorkshire Well-Being Limited | Health & social care | 2018 |
| YORKSHIREHOMES4U Ltd | Hospitality | 2022 |
| YOU BET Limited | Extraterritorial | 2011 |
| Young & Bowering Ltd | Information & communication | 2004 |
| Young Farmers Community Ltd | Other services | 2023 |
| Young Pharma Ltd | Wholesale & retail | 2023 |
| Young Propertyco Ltd | Households | 2019 |
| Your Future Vitality Ltd. | Health & social care | 2020 |
| Your Harrogate Limited | Information & communication | 2020 |
| Your Local Experiences Limited | Information & communication | 2025 |
| Your Media Group Limited | Information & communication | 2020 |
| Your Poll Ltd | Professional & scientific | 2020 |
| Your Sales Team Ltd | Professional & scientific | 2025 |
| Yourcare Yorkshire Limited | Health & social care | 2024 |
| Yummy by Design Ltd | Hospitality | 2022 |
| Yute Ltd | Manufacturing | 2019 |
| Zach Limited | Extraterritorial | 2023 |
| Zagell Limited | Professional & scientific | 2013 |
| Zahra ZIA Associates Limited | Construction | 2021 |
| Zake Ventures Ltd | Information & communication | 2022 |
| Zandermoor Limited | Real estate | 2020 |
| Zanita for Trade Ltd | Wholesale & retail | 2024 |
| Zank Limited | Professional & scientific | 2009 |
| Zaria Limited | Professional & scientific | 2015 |
| Zayo Global Reach UK Limited | Information & communication | 1999 |
| ZDJ Homestyle Ltd | Construction | 2025 |
| Zebra Interior Design Ltd | Professional & scientific | 2021 |
| Zebra Square Limited | Professional & scientific | 2003 |
| Zeitgeist Fine Art Limited | Wholesale & retail | 2014 |
| Zelst International Limited | Administrative & support | 2023 |
| Zelst Limited | Administrative & support | 2014 |
| ZEN Angel Properties Ltd Ltd | Real estate | 2025 |
| ZEN Kitchen Harrogate Ltd | Hospitality | 2026 |
| ZEN Sensory Ltd | Health & social care | 2023 |
| Zenith FM Limited | Extraterritorial | 2026 |
| Zenith Haven Ltd | Households | 2024 |
| Zenith Survey Equipment Limited | Extraterritorial | 1986 |
| Zenithra Holistics Ltd | Health & social care | 2025 |
| Zenton Limited | Real estate | 2018 |
| ZER01 Property Group Limited | Real estate | 2021 |
| Zermatt Scientific Limited | Wholesale & retail | 2024 |
| Zest 2.0 Limited | Information & communication | 2022 |
| Zest Cosmetics Limited | Wholesale & retail | 2014 |
| Zest Media Limited | Professional & scientific | 2021 |
| Zetland House Limited | Real estate | 2015 |
| Zettabit Limited | Information & communication | 2019 |
| Zhepa Limited | Hospitality | 2020 |
| Zhepa Two Ltd | Hospitality | 2025 |
| ZHI Developments Limited | Professional & scientific | 2020 |
| Zimon Limited | Extraterritorial | 2022 |
| Zincify Ltd | Information & communication | 2026 |
| Zink Limited | Extraterritorial | 2025 |
| ZJJ Properties Limited | Real estate | 2024 |
| ZMS Industries Ltd | Professional & scientific | 2020 |
| Zocca Holdings Limited | Professional & scientific | 2004 |
| Zondex Global Ltd | Transport & logistics | 2025 |
| Zondr Limited | Wholesale & retail | 2025 |
| Zone Trade Group Ltd | Wholesale & retail | 2023 |
| Zose Permanent Beauty Ltd | Other services | 2021 |
| ZOZAN47 Ltd | Hospitality | 2024 |
| ZS Music Consultants Limited | Administrative & support | 2020 |
| Zubrance Limited | Manufacturing | 1995 |
| Zuno Reserve Limited | Financial services | 2025 |
| Zuric (BTS) Ltd | Construction | 2011 |
| Élevé Group Limited | Financial services | 2025 |