| Dubai Dynamo Limited | Arts & recreation | 2009 |
| Dubbed UP Conversions Limited | Wholesale & retail | 2023 |
| Dubia Limited | Extraterritorial | 2025 |
| DUBL1N Ltd | Extraterritorial | 2021 |
| Duchy Accountants Limited | Professional & scientific | 2026 |
| Duchy Care Limited | Health & social care | 2022 |
| Duchy Chartered Accountants Limited | Professional & scientific | 2022 |
| Duchy Design Limited | Professional & scientific | 2013 |
| Duchy Healthcare Limited | Health & social care | 2023 |
| Duchy House Ltd | Administrative & support | 2010 |
| Duchy Investment Partners Limited | Extraterritorial | 2023 |
| Duchy Mews Management Co. Limited | Households | 1984 |
| Duchy Mount Management Co Ltd | Real estate | 2017 |
| Duchy Nominees Limited | Extraterritorial | 2023 |
| Duchy Private Office LLP | | 2017 |
| Duff Beer Limited | Extraterritorial | 2011 |
| Duncan & Co. Project Management Ltd | Financial services | 2025 |
| Duncan Street 1956 Limited | Extraterritorial | 2014 |
| Duncroft (Harrogate) Flat Management Company Limited | Households | 2019 |
| Dunhill Classics Limited | Extraterritorial | 2011 |
| Dunn Belmont Limited | Administrative & support | 2015 |
| Dunnington Holdings Ltd | Professional & scientific | 2019 |
| Dunster Consulting Limited | Administrative & support | 2008 |
| Dunton O'Neill Limited | Construction | 2018 |
| Duquesa Limited | Hospitality | 1984 |
| Durham Medicals Limited | Health & social care | 2019 |
| Dutch Stock House Limited | Extraterritorial | 2013 |
| Dutton and Associates Ltd | Professional & scientific | 2025 |
| DVV Properties 2 Limited | Real estate | 2015 |
| DW Building Consultancy Limited | Professional & scientific | 2020 |
| DW Freehold Limited | Real estate | 2017 |
| DW1 Ltd | Information & communication | 2024 |
| Dwelling Place Limited | Real estate | 1998 |
| DWS Developments Limited | Real estate | 2014 |
| DXM Digital Limited | Information & communication | 2020 |
| DXN Technologies Ltd | Information & communication | 2025 |
| Dy:Dx Consulting Limited | Administrative & support | 2006 |
| Dyan Reaveley Limited | Arts & recreation | 2013 |
| Dyche Design Ltd | Professional & scientific | 2005 |
| Dymo Limited | Extraterritorial | 2011 |
| DYNAM1TE Limited | Extraterritorial | 2021 |
| Dynamic Desirable Developments Ltd | Real estate | 2025 |
| Dynamic Drainage Ltd. | Professional & scientific | 2005 |
| Dynamic Motion Limited | Information & communication | 1999 |
| Dyson Tech Ltd | Extraterritorial | 2013 |
| D£Al Ltd | Extraterritorial | 2015 |
| E & S Environmental Services Limited | Professional & scientific | 2004 |
| E & S Holdings Limited | Professional & scientific | 2004 |
| E a Marketing Ltd | Professional & scientific | 2021 |
| E Benedict Associates Limited | Information & communication | 2024 |
| E Blog Ltd | Extraterritorial | 2012 |
| E BOY Ltd | Extraterritorial | 2012 |
| E Call Limited | Extraterritorial | 2012 |
| E Romans Holiday LET Limited | Real estate | 2024 |
| E Romans Property Ltd | Real estate | 2018 |
| E S Furniture Ltd | Manufacturing | 2018 |
| E-Dash Ltd | Wholesale & retail | 2021 |
| E.J.Parkinson & SON Limited | Administrative & support | 1968 |
| E.K Galaxy Ltd | Arts & recreation | 2016 |
| Eagle Hall Management Company Limited | Real estate | 2005 |
| Eagle Rock Property Limited | Real estate | 2014 |
| Eajh Ltd | Information & communication | 2019 |
| Early Bird Run Crew CIC | Health & social care | 2023 |
| Earned Global Ltd | Administrative & support | 2025 |
| Earth & Soul Ltd | Wholesale & retail | 2022 |
| Earth and Leaf Community Interest Company | Information & communication | 2023 |
| Earthly Aura Ltd | Wholesale & retail | 2023 |
| Earthmill Holdings Limited | Construction | 2013 |
| Earthmill Maintenance Limited | Manufacturing | 2017 |
| Easily Distrcted Limited | Information & communication | 2025 |
| East Riding Care 1 Limited | Wholesale & retail | 2019 |
| East Street (Leeds) Limited | Real estate | 2003 |
| East Thorpe Court Management Company Ltd | Households | 2022 |
| Eastern Heritage Limited | Extraterritorial | 2012 |
| Eastlake Solutions LP | | 2010 |
| Eastthorpe Court (Block B) Management Company Ltd | Households | 2025 |
| Easy AE Limited | Other services | 2014 |
| Easy United Limited | Administrative & support | 2007 |
| Eater Stop Limited | Hospitality | 2026 |
| Eaton Rifles Ltd | Extraterritorial | 2012 |
| Ebel Limited | Extraterritorial | 2011 |
| Ebor Fitness Limited | Arts & recreation | 2006 |
| Eboradiology Ltd | Health & social care | 2020 |
| Ebram for Trade Ltd | Wholesale & retail | 2021 |
| Ebru Evrim Limited | Arts & recreation | 2019 |
| EC Eyecare Ltd | Health & social care | 2012 |
| Eccl 2020 Limited | Agriculture & fishing | 2020 |
| Echo Central 2 Limited | Construction | 2006 |
| Eclatedge Fashion Ltd | Wholesale & retail | 2024 |
| Eco Laundry Club Ltd | Wholesale & retail | 2020 |
| Ecoball Limited | Wholesale & retail | 2012 |
| Ecodawn Ltd | Construction | 2025 |
| Ecogenetics Solutions Ltd | Wholesale & retail | 2024 |
| Ecogenix Renewables Ltd | Wholesale & retail | 2024 |
| Ecolex Limited | Construction | 2011 |
| Ecoline UK Ltd | Manufacturing | 2003 |
| Ecommerce Thinking Limited | Information & communication | 2021 |
| Ecosupport Limited | Administrative & support | 2007 |
| ED Psych Consultancy Limited | Education | 2023 |
| Ed's Property Services Ltd | Administrative & support | 2024 |