| Strathclyde Windscreens Limited | Manufacturing | 1994 |
| Strathy Contracts Ltd | Construction | 2016 |
| Street Food (Live) Ltd | Hospitality | 2026 |
| Strefford Tulips Limited | Professional & scientific | 2008 |
| Stretched Limited | Other services | 2024 |
| Stroits UK Limited | Professional & scientific | 2025 |
| Stroma Builders Ltd | Construction | 2019 |
| Stroma Property Ltd | Real estate | 2017 |
| Strucsure Engineering Consultants Limited | Professional & scientific | 2025 |
| STS Electrical Contractors Limited | Construction | 2007 |
| Stuart Gibson Cleaning Services Ltd | Administrative & support | 2009 |
| Stuart Hislop Ltd | Transport & logistics | 2018 |
| Studio 18 Kitchens & Interiors Ltd | Professional & scientific | 2021 |
| Studio DE Fleur Limited | Wholesale & retail | 2021 |
| Studios by the Unit Ltd | Arts & recreation | 2025 |
| Subcool (Air Conditioning) Limited | Energy | 2002 |
| Subcool Group Holdings Limited | Financial services | 2019 |
| Subcool Installations Limited | Energy | 2019 |
| Subcool IP Holdings Limited | Financial services | 2019 |
| Subcool Servicing Limited | Manufacturing | 2019 |
| Subgas Plumbing & Heating Ltd | Construction | 2026 |
| Success Equity Ltd | Professional & scientific | 2010 |
| Sugar Halo Limited | Wholesale & retail | 2025 |
| Suisse Clothing Company Ltd | Extraterritorial | 2019 |
| Summerstorm Bloodstock (Scotland) Limited | Agriculture & fishing | 2021 |
| Summersun Limited | Other services | 2017 |
| Sumoly Property Investment Ltd | Real estate | 2024 |
| Sumoly Trading Ltd | Real estate | 2024 |
| Sun 21 Limited | Other services | 2017 |
| Sun 365 Ltd | Other services | 2020 |
| Sun 51 Ltd | Other services | 2020 |
| Sun 71 Ltd | Other services | 2020 |
| Sun by EAR Ltd | Arts & recreation | 2013 |
| Sun Princess II Limited | | 2025 |
| Sun Princess Limited | | 2025 |
| Sun Shack Glenrothes Limited | Other services | 2014 |
| Sun Shack Limited | Arts & recreation | 2010 |
| Sunfit Limited | Other services | 2018 |
| Sunil Dhillon Productions Ltd | Professional & scientific | 2021 |
| Sunset Launderette Ltd | Other services | 2022 |
| Sunz Limited | Other services | 2017 |
| Superior Bathrooms Limited | Construction | 2013 |
| Supersave Properties Ltd | Real estate | 2016 |
| Support for Play & Early Learning in Lanarkshire (Spell) | Health & social care | 2005 |
| Support Technology Limited | Extraterritorial | 2025 |
| Supreme Snacks Ltd | Hospitality | 2020 |
| Surana Ltd | Real estate | 2017 |
| Surgiconcept Ltd | Other services | 2016 |
| Susan Dunsmore Limited | Professional & scientific | 2006 |
| Suzanne Esper Limited | Wholesale & retail | 2020 |
| SW Hamilton 3 Ltd | Hospitality | 2025 |
| SW Vent Ltd | Construction | 2023 |
| Swaddle Lanarkshire | Wholesale & retail | 2015 |
| Swarnshikhar Restaurants Ltd | Hospitality | 2026 |
| Sweetology Ltd | Wholesale & retail | 2023 |
| SWH Limited | Administrative & support | 2024 |
| Swimming Pool Filtration Ltd. | Professional & scientific | 2002 |
| Swiss LUX Consulting Ltd | Professional & scientific | 2023 |
| Switchgear Solutions Ltd | Construction | 2024 |
| Sycorax Limited | | 2023 |
| Sylvia Properties Ltd | Real estate | 2020 |
| Symingtons Plumbing and Heating Limited | Construction | 2014 |
| Synchronize Therapy Ltd | Health & social care | 2025 |
| Synergy INK Tattoo Ltd | Other services | 2026 |
| Synergy Project Controls Ltd | Administrative & support | 2017 |
| Synergy Tradeco UK Limited | Water & waste | 2020 |
| Synergy Training Services Limited | Education | 2022 |
| Syntharis Health Ltd | Information & communication | 2025 |
| Synthetic Solutions Group Limited | Professional & scientific | 2018 |
| SZ Carpentry Ltd | Manufacturing | 2025 |
| T & K Olivers Properties Limited | Real estate | 2020 |
| T & N Marathon Ltd | Real estate | 2019 |
| T'S Realty Limited | Other services | 2023 |
| TA the Best Ltd | Wholesale & retail | 2025 |
| Tacho Data Ltd. | Administrative & support | 2007 |
| Tada Technology Limited | Information & communication | 2018 |
| Tafw Ltd | Extraterritorial | 2013 |
| TAI CHI Acupuncture Centre Ltd | Health & social care | 2018 |
| TAI CHI Healing Centre Ltd | Health & social care | 2013 |
| Tale of Two Trading Ltd | Wholesale & retail | 2018 |
| Talmaciu Ltd | Real estate | 2025 |
| TAM Property Investments Ltd | Real estate | 2018 |
| Tamana Limited | | 2023 |
| Tamarisk (Scotland) Ltd | Real estate | 2022 |
| Tanariah Magaba Ltd | Health & social care | 2022 |
| Tanerife Limited | Other services | 2021 |
| Tang's Restaurant Ltd | Hospitality | 2010 |
| Tanna Training Ltd | Education | 2023 |
| Tanning Concepts Limited | Other services | 2014 |
| Tanz (2004) Limited | Professional & scientific | 2004 |
| Tanz Limited | Other services | 2010 |
| Tanz Tanning Ltd | Other services | 2010 |
| TAP House Investments Limited | Real estate | 2025 |
| Target Night Life Ltd | Arts & recreation | 2025 |
| Target Online Ltd | Wholesale & retail | 2021 |
| Tartan Latte Limited | Hospitality | 2025 |
| Tartarus-Tcg Ltd | Wholesale & retail | 2024 |
| Tasty Bites (Glasgow) Ltd | Hospitality | 2015 |
| Tattoos by Inverink Limited | Other services | 2026 |
| Tavor Holdings Limited | | 2023 |