| Ultra Finishing Limited | Manufacturing | 1984 |
| Ultrasyntec Limited | Construction | 1996 |
| Umrah Supermarket Halifax Ltd | Wholesale & retail | 2025 |
| Uncle Teds Limited | Agriculture & fishing | 2019 |
| Under OUR Mattress Ltd | Health & social care | 2021 |
| Underhill Properties (Halifax) Limited | Construction | 2018 |
| Unicart London Limited | Wholesale & retail | 2024 |
| Unified Acquisition Ltd | Financial services | 2023 |
| Unified Property Ltd | Real estate | 2018 |
| Unify PR & Marketing Limited | Professional & scientific | 2019 |
| Unionex Ltd | Wholesale & retail | 2026 |
| Unique Carpets & Rugs Limited | Wholesale & retail | 2015 |
| Unique Community Hub Ltd | Arts & recreation | 2018 |
| Unique Ways | Health & social care | 2004 |
| Unit Move Limited | Information & communication | 2015 |
| United Renewables Limited | Professional & scientific | 1995 |
| Universal Commercial Vehicles (Export) Limited | Wholesale & retail | 1998 |
| Unmasked Mental Health | Other services | 2019 |
| Uomobuono Limited | Other services | 2007 |
| UP Socks Ltd | Wholesale & retail | 2026 |
| UP the Creek Ltd | Hospitality | 2025 |
| Upholstery Master Ltd | Manufacturing | 2024 |
| Uphx Ltd | Arts & recreation | 2026 |
| Uplds Ltd | Arts & recreation | 2026 |
| Upper George Yard Limited | Construction | 2016 |
| Uptown Boutique Limited | Wholesale & retail | 2016 |
| Urban Esquire (Brighouse) Limited | Other services | 2019 |
| Urban Facilities Management Ltd | Administrative & support | 2024 |
| Urban IT Support Ltd | Wholesale & retail | 2012 |
| Urban Sky Ventures Ltd | Wholesale & retail | 2025 |
| Urban Zeniths Ltd | Wholesale & retail | 2025 |
| Urgent Forwarding Limited | Transport & logistics | 2016 |
| Urth Holdings Ltd | Hospitality | 2026 |
| US Dent Ltd | Health & social care | 2025 |
| Usher Joinery Sevices Limited | Manufacturing | 2015 |
| UTB Property Limited | Real estate | 2017 |
| Utilities&Marketing Ltd | Wholesale & retail | 2025 |
| UTO Environmental Products Limited | Wholesale & retail | 2008 |
| Uzair Transport Limited | Transport & logistics | 2022 |
| Uzmaila Ltd | Professional & scientific | 2019 |
| V & R Sessions Ltd | Wholesale & retail | 2015 |
| V&D GN Ltd | Hospitality | 2025 |
| V1 Engineering Limited | Manufacturing | 2007 |
| Vale Mill Management Limited | Households | 2000 |
| Valehorizonhomes Ltd | Real estate | 2025 |
| Valemont Group Ltd | Financial services | 2026 |
| Valid Properties Ltd | Real estate | 2024 |
| Valley Construction (Yorkshire) Limited | Construction | 2015 |
| Valley Fire & Security Ltd | Administrative & support | 2023 |
| Valley Fit Gym Ltd | Arts & recreation | 2021 |
| Valley Insulation Ltd | Construction | 2025 |
| Valley Wellness Ltd | Other services | 2025 |
| Valquest Ltd | Extraterritorial | 2000 |
| Valuassist Ltd | Information & communication | 2026 |
| Value Exchange Ltd | Professional & scientific | 2014 |
| Van Bros Ltd | Transport & logistics | 2025 |
| Van Doctor Ltd | Wholesale & retail | 2024 |
| Vandaled Technologies Ltd | Extraterritorial | 2015 |
| Vangaard Design and Acquisition Limited | Professional & scientific | 2021 |
| Vanguard Elite Ltd | Real estate | 2024 |
| Vantage Point Group Limited | Professional & scientific | 2026 |
| Vantage Warehouse Limited | Wholesale & retail | 2024 |
| Vaon Services Ltd | Professional & scientific | 2026 |
| Vape & Chill Limited | Wholesale & retail | 2026 |
| Vapestation Inc Limited | Wholesale & retail | 2015 |
| Vaporetto Coffee Machines Ltd | Manufacturing | 2022 |
| Varda Healthcare Ltd | Health & social care | 2026 |
| Vardies Planning Consultancy Limited | Information & communication | 2004 |
| Vaughan Steels Ltd | Wholesale & retail | 2016 |
| Vaulltix Limited | Other services | 2020 |
| VAULT5DIGITAL Ltd | Professional & scientific | 2026 |
| VB (Halifax) Ltd | Professional & scientific | 2023 |
| VB Properties (HX) Ltd | Financial services | 2017 |
| VBT Consulting Ltd | Professional & scientific | 2023 |
| VCF Frozen Foods Limited | | 1982 |
| VE Design Services Ltd | Professional & scientific | 2008 |
| Vecreative Ltd | Other services | 2019 |
| Vector Distribution Limited | Transport & logistics | 2002 |
| Vegovision Limited | Professional & scientific | 2011 |
| Velocity Auto Salvage Cars Ltd | Wholesale & retail | 2023 |
| Velocity Dynamics Ltd | Wholesale & retail | 2025 |
| Veloria Finds Ltd | Wholesale & retail | 2025 |
| Vend Tech Services Ltd | Wholesale & retail | 2024 |
| Vendabus Ltd | Wholesale & retail | 2023 |
| Vending Design & Manufacture Ltd | Extraterritorial | 2025 |
| Venezia Properties (Doncaster) Limited | Real estate | 2025 |
| Veni Vidi Holdings Limited | Financial services | 2019 |
| Veni Vidi Medical Limited | Wholesale & retail | 2009 |
| Venture & Impetus Limited | Water & waste | 2022 |
| Venture Forge Industries Ltd | Information & communication | 2007 |
| Venture Health Ltd | Professional & scientific | 2024 |
| Venus Nails VT Ltd | Other services | 2024 |
| Verdant Specialty Solutions Halifax Limited | Manufacturing | 2020 |
| Verdi ASH Limited | Wholesale & retail | 2025 |
| Verite Production Limited | Professional & scientific | 2025 |
| Veritiara Limited | Wholesale & retail | 2026 |
| Verity a Kunman Ltd | Professional & scientific | 2025 |
| Vespa Pest Control Ltd | Other services | 2024 |
| Veyila Rentals Ltd | Real estate | 2022 |
| VEÉ Freelance Ltd | Wholesale & retail | 2020 |