| Elyte Motors Ltd | Wholesale & retail | 2024 |
| EM JS Catering Halifax Limited | Hospitality | 2026 |
| Email Wins Ltd | Information & communication | 2024 |
| Embedded Control Systems Ltd | Information & communication | 2012 |
| Ember Coffee Ltd | Hospitality | 2026 |
| Emberprise Ltd | Construction | 2022 |
| Emberprise Tanning Limited | Other services | 2024 |
| Emberstone Projects Ltd | Wholesale & retail | 2025 |
| Emerald Counselling Psychology Ltd | Health & social care | 2019 |
| Emerald Green Holdings (Yorkshire) Ltd | Financial services | 2025 |
| Emerald Green Investments Limited | Construction | 2001 |
| Emerald Lounge & Restaurant Ltd | Hospitality | 2026 |
| Emergency Medicine Studies Ltd | Health & social care | 2024 |
| Emergent Crown Contract Office Furnishings Limited | Wholesale & retail | 1988 |
| Emily P Ltd | Wholesale & retail | 2021 |
| Emlo Properties Ltd | Real estate | 2024 |
| Emmabeth Limited | Real estate | 2014 |
| Emora Eating Disorder Recovery CIC | Education | 2026 |
| Emotions Funeral Services Limited | Other services | 2013 |
| Emotions Memorial Limited | Other services | 2016 |
| Empire Exhibitions & Events Ltd | Professional & scientific | 2025 |
| Empower Sport Limited | Other services | 2024 |
| Empowered Fitness Training Limited | Education | 2024 |
| EMS Tuition Ltd | Education | 2023 |
| EMY & Khalid Limited | Health & social care | 2023 |
| Enchanted Hair Drops Ltd | Other services | 2026 |
| Encompassebuild Services Ltd | Construction | 2026 |
| Endeavour Sailing Limited | Administrative & support | 2004 |
| Enderby Notary Limited | Professional & scientific | 2015 |
| Endorphins Group Ltd | Education | 2019 |
| Endres UK Limited | Wholesale & retail | 2004 |
| Enefer Holdings Limited | Financial services | 2022 |
| Energize Care Limited | Health & social care | 2017 |
| Energy Advice Centre Limited | Construction | 1995 |
| Energy Reduction Services Ltd | Construction | 2021 |
| Energycloud Social Enterprise CIC | Energy | 2025 |
| Engine Social Limited | Hospitality | 2017 |
| Engineered Timber Specialists Ltd | Professional & scientific | 2024 |
| Enigma Accountants Limited | Professional & scientific | 2021 |
| Entech Clinical Support Services Ltd | Administrative & support | 2023 |
| Entech Services (UK) Limited | Construction | 2013 |
| Enterprise Automation Services Ltd | Information & communication | 2016 |
| Entice Fragrances Ltd | Extraterritorial | 2020 |
| Envirowaste Services Limited | Water & waste | 1999 |
| Envoyjade Limited | Financial services | 1985 |
| Envy Solutions Ltd | Information & communication | 2006 |
| Enzo Secuirty Solutions Ltd | Administrative & support | 2025 |
| EOJ 2 Ltd | Arts & recreation | 2024 |
| Eona Green Limited | Manufacturing | 2024 |
| EP Seven Developments Ltd | Construction | 2019 |
| EPC Calderdale Ltd | Professional & scientific | 2024 |
| Epicframe Innovations Ltd | Wholesale & retail | 2025 |
| Epitome IT Consulting Limited | Information & communication | 2017 |
| Epos Bookings Ltd | Information & communication | 2020 |
| EPS Leeds Property Ltd | Real estate | 2025 |
| EQ Care Ltd | Administrative & support | 2023 |
| Equanimity (STH) Ltd | Administrative & support | 2023 |
| Equip IT Supplies Ltd | Wholesale & retail | 2024 |
| Equityway Investment 2 Ltd | Construction | 2025 |
| Equityway Investment 3 Ltd | Construction | 2026 |
| Equityway Investment 4 Ltd | Construction | 2026 |
| Equityway Investment 5 Ltd | Construction | 2026 |
| ER Creative Limited | Professional & scientific | 2020 |
| ERA UK Plastics Ltd | Wholesale & retail | 2023 |
| ERC Property Limited | Real estate | 2021 |
| ERH Investments Limited | Professional & scientific | 2018 |
| ERI Interiors Ltd | Professional & scientific | 2018 |
| ERI Properties Limited | Real estate | 2021 |
| Eris-K Property Renovations and Maintenance Ltd | Construction | 2020 |
| ES & Co Stays Ltd | Real estate | 2026 |
| ES Maths Ltd | Other services | 2026 |
| Escapageddon Limited | Arts & recreation | 2020 |
| Escape the Mill Limited | Arts & recreation | 2020 |
| ESE NE Tekyerema CIC | Information & communication | 2024 |
| Eshma London Ltd | Wholesale & retail | 2025 |
| ESK Sharma Ltd | Real estate | 2025 |
| ESL Property Limited | Real estate | 2025 |
| ESP Total Services Limited | Administrative & support | 2017 |
| Essential Foods Trading Ltd | Extraterritorial | 2011 |
| ESW Audit Services Limited | Financial services | 2013 |
| Etar BG Ltd | Hospitality | 2024 |
| Ethics in Education Limited | Education | 2020 |
| Ethos Foods (UK) Limited | Hospitality | 2013 |
| Ethos Hotel Management Services Ltd. | Professional & scientific | 2018 |
| ETJ Services Ltd | Information & communication | 2017 |
| Etradis Corporation Limited | Extraterritorial | 1992 |
| EU Furniture Wholesale Limited | Wholesale & retail | 2016 |
| Euro Trade Halifax Ltd | Wholesale & retail | 2025 |
| Euromech Installations Limited | Manufacturing | 2018 |
| Euromedics (Global) Ltd | Other services | 2020 |
| Europa International Group Ltd | Professional & scientific | 2015 |
| Europa NAS Ltd | Hospitality | 2020 |
| European Foods Store (Halifax) Ltd | Wholesale & retail | 2021 |
| EVA Joyce Bridal Limited | Wholesale & retail | 2022 |
| Eva-Pak Ltd | Professional & scientific | 2022 |
| Evans Public Houses Ltd | Hospitality | 2022 |
| Evans Webb Publishing Limited | Information & communication | 2024 |
| EVE Lake Conveyancing & Legal Services Ltd | Professional & scientific | 2019 |
| Evehow Ltd | Information & communication | 2023 |
| Eventco Ltd | Hospitality | 2023 |