| Projection Rendering Ltd. | Construction | 2005 |
| Promise Risk Management Partnership LLP | | 2019 |
| Pronashe Health Care Ltd | Health & social care | 2012 |
| Propertunity 360 Limited | Hospitality | 2023 |
| Property Advanced Ltd | Administrative & support | 2024 |
| Property by Design Ltd | Real estate | 2024 |
| PRS Estates Ltd | Real estate | 2019 |
| Pryke Homes Limited | Construction | 2014 |
| Prymi Ltd | Information & communication | 2026 |
| Psychological Studies International Limited | Education | 2019 |
| PTB Brickwork Limited | Construction | 2002 |
| Publicity Systems Limited | Administrative & support | 2008 |
| Pump House Productions International Limited | Administrative & support | 1994 |
| PUR - Pulse Limited | Arts & recreation | 2025 |
| Purnima Fragrances Ltd | Manufacturing | 2023 |
| Purplepaper Limited | Administrative & support | 2006 |
| Putland Limited | Administrative & support | 2020 |
| Puttick Plumbing and Heating Ltd | Construction | 2021 |
| Pxlwave Limited | Administrative & support | 2024 |
| Pyroborn Limited | Administrative & support | 2013 |
| PZ Holdings & Design Ltd | Real estate | 2021 |
| Qauntflux Ltd | Professional & scientific | 2025 |
| QC Management Services LLP | | 2018 |
| Quality Reliable Care Limited | Health & social care | 2008 |
| Quality Services Hygiene Supplies Ltd | Wholesale & retail | 2003 |
| Quantic LAB UK Limited | Information & communication | 2020 |
| Quest Project Services Limited | Real estate | 1997 |
| Questbell Limited | Administrative & support | 2009 |
| Quick Brown FOX PR Ltd | Professional & scientific | 2006 |
| Quiver Tree Consultants Limited | Administrative & support | 2017 |
| Quotacom Digital Services Ltd | Administrative & support | 2018 |
| R & D Construction (Sussex) Limited | Construction | 2014 |
| R and C Beale Properties Ltd | Real estate | 2017 |
| R Ayyash Limited | Other services | 2018 |
| R F Environmental Limited | Professional & scientific | 2016 |
| R G Anaesthetics Ltd | Health & social care | 2017 |
| R G Brickwork (Sussex) Limited | Construction | 2018 |
| R P Taylor Limited | Administrative & support | 2002 |
| R S Electrical (RSW) Limited | Construction | 2009 |
| R Slack Limited | Health & social care | 2012 |
| R Taylor Plumbing & Heating Ltd | Construction | 2023 |
| R. J. G. Services Ltd | Construction | 2015 |
| R.C Divine Ltd | Hospitality | 2021 |
| R.P. Meats Wholesale Limited | Wholesale & retail | 1977 |
| R8 Developments Limited | Construction | 2012 |
| Racecarpeople Ltd | Professional & scientific | 2014 |
| Rade Contracts Ltd | Transport & logistics | 2024 |
| Rade Services Ltd | Transport & logistics | 2020 |
| Radiant Balance Limited | Professional & scientific | 2016 |
| Radtastic Theatre C.I.C. | Arts & recreation | 2022 |
| Raimondzia Ltd | Wholesale & retail | 2023 |
| Rajdoot Divine Indian Limited | Hospitality | 2025 |
| Ramsden Properties Limited | Real estate | 2021 |
| Rance Investigations Ltd | Professional & scientific | 2018 |
| Rascals Vouchers Limited | Administrative & support | 2005 |
| Rawcrest Developments Ltd | Construction | 2025 |
| RAY Moore Construction Limited | Construction | 2013 |
| Raytel Ltd | Health & social care | 2024 |
| RB Health & Safety Solutions Limited | Professional & scientific | 2003 |
| Rbbc Beer Club Ltd | Wholesale & retail | 2023 |
| RBH Helicopters Limited | Administrative & support | 2024 |
| RD Custombikes Ltd | Wholesale & retail | 2014 |
| Realise (Europe) Limited | Administrative & support | 2000 |
| Realistic Project Management Limited | Professional & scientific | 2000 |
| Rebourne Recovery C.I.C. | Health & social care | 2020 |
| Recursively Ltd | Information & communication | 2026 |
| Recycle Bike Hire Ltd | Administrative & support | 2025 |
| Red Star Security Solutions Ltd | Information & communication | 2020 |
| Red Top Commercial Investments Limited | Real estate | 2021 |
| Red Top Group (Sussex) Limited | Professional & scientific | 2011 |
| Red Top Investments Limited | Real estate | 2018 |
| Red Top Lettings Limited | Real estate | 2011 |
| Red Top Limited | Real estate | 2001 |
| Red Top Properties Limited | Real estate | 2013 |
| Red Top Sales & Lettings Limited | Real estate | 2024 |
| Red Whiskey (Holdings) Limited | Financial services | 2024 |
| Red's Landscaping Limited | Administrative & support | 2003 |
| Redcat Marketing Limited | Administrative & support | 2002 |
| Redman Residential Limited | Construction | 2017 |
| Redroofs (Sussex) Limited | Real estate | 2018 |
| Redroofs Builders Ltd | Construction | 2023 |
| Redroofs Land Limited | Real estate | 2018 |
| Reed Roofing (South) Ltd | Construction | 2023 |
| Reefcom Airtime Limited | Information & communication | 2025 |
| Reefcom Limited | Administrative & support | 2011 |
| Reformery Barbers Ltd | Other services | 2019 |
| Refurbit Ltd | Information & communication | 2024 |
| Register of Water Engineers and Specialists Ltd | Administrative & support | 2018 |
| Rehab 4U Limited | Other services | 2013 |
| Renewity Limited | Financial services | 2020 |
| Renovate South Coast Ltd | Construction | 2026 |
| Renown Travel Limited | Transport & logistics | 2020 |
| Reservoir Frogs Limited | Real estate | 2020 |
| Resilience Constellation Holdings Limited | Other services | 2021 |
| Resystems Ltd | Manufacturing | 2010 |
| Revelec Electrical Limited | Construction | 2024 |
| Review Sample Product Recycling Limited | Administrative & support | 2023 |
| Revolve IT Services Ltd | Information & communication | 2024 |
| Rexblue Limited | Professional & scientific | 2010 |
| Reyno Properties Ltd | Real estate | 2025 |