| Roots 2022 Ltd | Real estate | 2022 |
| Rosebud Homes Limited | Real estate | 2022 |
| Rosemary Avenue Grimsby Management Company Limited | Households | 2017 |
| Rosewood Rental UK Ltd | Other services | 2018 |
| Ross Davy Limited | Professional & scientific | 1997 |
| Ross Developments Limited | Real estate | 2025 |
| Ross Jones Tree Services Limited | Administrative & support | 2017 |
| Ross Mechanical Services Limited | Information & communication | 2014 |
| Rothenburg Industrial Doors Ltd | Professional & scientific | 2026 |
| Rothenburg Limited | Information & communication | 2025 |
| Rothmere & Co Logistics Ltd | Transport & logistics | 2026 |
| Rotio Ltd | Information & communication | 2026 |
| Rotor Commissioning Services Limited | Professional & scientific | 2007 |
| Rouleaux Ltd | Information & communication | 2020 |
| Routh Business Solutions Ltd | Professional & scientific | 2026 |
| Rowlands Property Investments Limited | Construction | 2023 |
| Rowlands Reupholstery Expert Limited | Manufacturing | 2015 |
| ROY Hughes Enterprises Ltd | Construction | 2015 |
| Royall Plumbing & Heating Limited | Construction | 2016 |
| Rozario Care Ltd | Health & social care | 2018 |
| Rozh International Ltd | Wholesale & retail | 2024 |
| Rozitech Engineering Ltd | Professional & scientific | 2022 |
| RP Ceilings & Interiors Limited | Construction | 2017 |
| RP Newtown DEV Ltd | Construction | 2012 |
| RP Venture Group Ltd | Arts & recreation | 2025 |
| RPB Design & Build Limited | Construction | 2016 |
| RPM Group Limited | Water & waste | 2016 |
| Rpqa Ltd | Extraterritorial | 2020 |
| RR Grimsby Ltd | Wholesale & retail | 2025 |
| RR Holistic Care North East Lincolnshire Ltd | Health & social care | 2021 |
| RRC Grimsby Property Limited | Real estate | 2025 |
| RS E and I Services Ltd | Energy | 2018 |
| RS Sutton Holdings Ltd | Financial services | 2023 |
| RSB Flooring Contractors Limited | Construction | 2009 |
| RSC Joinery and Building Services Ltd | Construction | 2021 |
| RSG Decorators Limited | Construction | 2016 |
| RSG Group Lincs Limited | Construction | 2023 |
| RSK Health Limited | Health & social care | 2025 |
| RSM Service Group Limited | Administrative & support | 2025 |
| Rssas Ltd | Professional & scientific | 2010 |
| Rssr (UK) Limited | Professional & scientific | 2024 |
| Rsuk Repairs Limited | Extraterritorial | 2022 |
| Rsuk Solar Limited | Extraterritorial | 2022 |
| Rsuk Wind Limited | Extraterritorial | 2022 |
| RT Architects Ltd | Professional & scientific | 2024 |
| RT ENG Ltd | Construction | 2026 |
| RT JMW Properties Ltd | Real estate | 2025 |
| RTC Digital Ltd | Wholesale & retail | 2018 |
| RTS Motors Ltd | Wholesale & retail | 2017 |
| Ruben SRL Limited | Transport & logistics | 2024 |
| Rubix Response Limited | Administrative & support | 2018 |
| Ruby Blue Home Limited | Manufacturing | 2022 |
| Rundle Property Group Ltd | Real estate | 2022 |
| Rundle Property Investment Ltd | Real estate | 2019 |
| Runrug Group Ltd | Wholesale & retail | 2025 |
| Runrug Ltd | Manufacturing | 2019 |
| Rush Inspection Limited | Energy | 2018 |
| Russian Interpreter Limited | Professional & scientific | 2009 |
| Ruth Brewin Limited | Extraterritorial | 2012 |
| Ruth Oliver Medical Aesthetics Limited | Health & social care | 2022 |
| Rutreb Limited | Health & social care | 2011 |
| RW Aesthetics ( Lincs.) Ltd. | Health & social care | 2018 |
| RW Maintenance & Management Limited | Professional & scientific | 2026 |
| RW Refrigeration Ltd | Administrative & support | 2017 |
| RW Site Services Ltd | Professional & scientific | 2025 |
| RWC Property Ltd | Real estate | 2023 |
| RWS Carpet Fitters Supplies Ltd | Wholesale & retail | 2022 |
| RXG Ltd | Real estate | 2021 |
| Ryan Vickers Racing Limited | Professional & scientific | 2018 |
| Rychotrans Ltd | Transport & logistics | 2014 |
| Ryco Media Ltd | Information & communication | 2025 |
| RZD Developments Ltd | Real estate | 2025 |
| S & C Staintech Limited | Manufacturing | 2002 |
| S & G Services ( Lincs.) Ltd | Construction | 2026 |
| S & J Electrical Services Ltd | Construction | 2024 |
| S & L Assets Limited | Real estate | 2018 |
| S & S Leisure Limited | Arts & recreation | 1978 |
| S & S Property Developments Limited | Construction | 2023 |
| S Alavala Limited | Health & social care | 2012 |
| S Allen Groundworks Limited | Construction | 2022 |
| S and T Cars Grimsby Limited | Transport & logistics | 2025 |
| S Ayim Limited | Financial services | 2017 |
| S B & R Taxis Ltd | Transport & logistics | 2013 |
| S B Neal Limited | Wholesale & retail | 2019 |
| S B Personnel Limited | Wholesale & retail | 2008 |
| S Baxter Ltd | Transport & logistics | 2019 |
| S C Precision Construction Ltd | Construction | 2021 |
| S D Ramsden & Co Limited | Wholesale & retail | 2012 |
| S D Ramsden Trustee Limited | Administrative & support | 2017 |
| S D S Installations Limited | Information & communication | 2003 |
| S E Large-Taylor Limited | Construction | 2007 |
| S E Norman Joinery Ltd | Construction | 2012 |
| S E-Commerce GBR Ltd | Wholesale & retail | 2022 |
| S Grantham Limited | Manufacturing | 2003 |
| S J Delves Limited | Extraterritorial | 2022 |
| S J Shaw Construction Ltd | Construction | 2022 |
| S Joinery 4U Limited | Construction | 2022 |
| S K Scaffolding Services ( Lincs.) Ltd | Construction | 2025 |
| S Loudon Automotive Ltd | Wholesale & retail | 2024 |
| S M & a Properties Limited | Construction | 2018 |